James L. Hougland, Ph.D.

Affiliations: 
2005-2010 Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
 2010- Chemistry Syracuse University, Syracuse, NY, United States 
Area:
chemistry and biochemistryof nucleic acids
Website:
https://hougland.expressions.syr.edu/
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SNBCP

Parents

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Joseph A. Piccirilli grad student 2005 Chicago
 (Investigating the structural and functional basis of catalysis in the Tetrahymena group I ribozyme.)
Carol A. Fierke post-doc 2005-2010 University of Michigan

Children

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Joseph Edgar Darling grad student 2010-2015 Syracuse
Susan Clare Flynn grad student 2010-2015 Syracuse
Soumyashree A Gangopadhyay grad student 2011-2016 Syracuse
Kayleigh McGovern-Gooch grad student 2012-2017 Syracuse
Melanie Jane Blanden grad student 2011-2018 Syracuse
Elizabeth Rose Cleverdon grad student 2013-2018 Syracuse
Maria Campana grad student 2014-2020 Syracuse
Sudhat Ashok grad student 2015-2020 Syracuse
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Publications

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Schey GL, Buttery PH, Hildebrandt ER, et al. (2021) MALDI-MS Analysis of Peptide Libraries Expands the Scope of Substrates for Farnesyltransferase. International Journal of Molecular Sciences. 22
Davis TR, Pierce MR, Novak SX, et al. (2021) Ghrelin octanoylation by ghrelin -acyltransferase: protein acylation impacting metabolic and neuroendocrine signalling. Open Biology. 11: 210080
Deschaine SL, Farokhnia M, Gregory-Flores A, et al. (2021) A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data. Addiction Biology. e13033
Wang Y, Kilic O, Csizmar CM, et al. (2020) Engineering reversible cell-cell interactions using enzymatically lipidated chemically self-assembled nanorings. Chemical Science. 12: 331-340
Moose JE, Leets KA, Mate NA, et al. (2020) An overview of ghrelin -acyltransferase inhibitors: a literature and patent review for 2010-2019. Expert Opinion On Therapeutic Patents. 1-13
Ashok S, Hildebrandt ER, Ruiz CS, et al. (2020) Protein Farnesyltransferase Catalyzes Unanticipated Farnesylation and Geranylgeranylation of Shortened Target Sequences. Biochemistry
Abizaid A, Hougland JL. (2019) Ghrelin Signaling: GOAT and GHS-R1a Take a LEAP in Complexity. Trends in Endocrinology and Metabolism: Tem
Campaña MB, Irudayanathan FJ, Davis TR, et al. (2019) The ghrelin -acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation. The Journal of Biological Chemistry
Sieburg MA, Cleverdon ER, Hougland JL. (2019) Biochemical Assays for Ghrelin Acylation and Inhibition of Ghrelin O-Acyltransferase. Methods in Molecular Biology (Clifton, N.J.). 2009: 227-241
Hougland JL. (2019) Ghrelin octanoylation by ghrelin -acyltransferase: Unique protein biochemistry underlying metabolic signaling. Biochemical Society Transactions
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