Shawn D. Walker, Ph.D.
Affiliations: | 2002 | University of British Columbia, Vancouver, Vancouver, BC, Canada |
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"Shawn Walker"Mean distance: 8.99 | S | N | B | C | P |
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Sign in to add mentor| Edward Piers | grad student | 2002 | UBC | |
| (A synthetic approach to the variecolin class of sesterterpenoids: Total syntheses of (+/-)-5-deoxovariecolin, (+/-)-5-deoxyvariecolol and (+/-)-5-deoxyvariecolactone. A new cycloheptenone annulation method employing the bifunctional reagent (Z)-5-iodo-1-t) | ||||
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Publications
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| Maloney AJ, Içten E, Capellades G, et al. (2020) A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 3: Manganese-Catalyzed Asymmetric Epoxidation, Crystallization, and Filtration Organic Process Research & Development |
| Icten E, Maloney A, Beaver MG, et al. (2020) A virtual plant for integrated continuous manufacturing of a carfilzomib drug substance intermediate. Part 2: enone synthesis via a Barbier-type Grignard process Organic Process Research & Development |
| Içten E, Maloney AJ, Beaver MG, et al. (2020) A virtual plant for integrated continuous manufacturing of a carfilzomib drug substance intermediate. Part 1: CDI-promoted amide-bond formation Organic Process Research & Development |
| Beaver MG, Shi X, Riedel J, et al. (2020) Continuous Process Improvement in the Manufacture of Carfilzomib, Part 2: An Improved Process for Synthesis of the Epoxyketone Warhead Organic Process Research & Development. 24: 490-499 |
| Dornan PK, Anthoine T, Beaver MG, et al. (2020) Continuous Process Improvement in the Manufacture of Carfilzomib, Part 1: Process Understanding and Improvements in the Commercial Route to Prepare the Epoxyketone Warhead Organic Process Research & Development. 24: 481-489 |
| Caille S, Cui S, Faul MM, et al. (2019) Molecular Complexity as a Driver for Chemical Process Innovation in the Pharmaceutical Industry. The Journal of Organic Chemistry |
| Caille S, Allgeier AM, Bernard C, et al. (2019) Development of a Factory Process for Omecamtiv Mecarbil, a Novel Cardiac Myosin Activator Organic Process Research & Development. 23: 1558-1567 |
| Cochran BM, Corbett MT, Correll TL, et al. (2018) Development of a Commercial Process to Prepare AMG 232 Using A Green Ozonolysis-Pinnick Tandem Transformation. The Journal of Organic Chemistry |
| Kasparian AJ, Savarin C, Allgeier AM, et al. (2011) Selective catalytic hydrogenation of nitro groups in the presence of activated heteroaryl halides. The Journal of Organic Chemistry. 76: 9841-4 |
| Caille S, Crockett R, Ranganathan K, et al. (2011) Catalytic asymmetric synthesis of a tertiary benzylic carbon center via phenol-directed alkene hydrogenation. The Journal of Organic Chemistry. 76: 5198-206 |