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Shawn D. Walker, Ph.D. - Publications

Affiliations: 
2002 University of British Columbia, Vancouver, Vancouver, BC, Canada 
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Maloney AJ, Içten E, Capellades G, Beaver MG, Zhu X, Graham LR, Brown DB, Griffin DJ, Sangodkar R, Allian A, Huggins S, Hart R, Rolandi P, Walker SD, Braatz RD. A Virtual Plant for Integrated Continuous Manufacturing of a Carfilzomib Drug Substance Intermediate, Part 3: Manganese-Catalyzed Asymmetric Epoxidation, Crystallization, and Filtration Organic Process Research & Development. DOI: 10.1021/Acs.Oprd.0C00189  0.36
2020 Icten E, Maloney A, Beaver MG, Zhu X, Shen DE, Robinson JA, Parsons AT, Allian A, Huggins S, Hart R, Rolandi P, Walker SD, Braatz RD. A virtual plant for integrated continuous manufacturing of a carfilzomib drug substance intermediate. Part 2: enone synthesis via a Barbier-type Grignard process Organic Process Research & Development. DOI: 10.1021/Acs.Oprd.0C00188  0.337
2020 Içten E, Maloney AJ, Beaver MG, Shen DE, Zhu X, Graham LR, Robinson JA, Huggins S, Allian A, Hart R, Walker SD, Rolandi P, Braatz RD. A virtual plant for integrated continuous manufacturing of a carfilzomib drug substance intermediate. Part 1: CDI-promoted amide-bond formation Organic Process Research & Development. DOI: 10.1021/Acs.Oprd.0C00187  0.334
2020 Beaver MG, Shi X, Riedel J, Patel P, Zeng A, Corbett MT, Robinson JA, Parsons AT, Cui S, Baucom K, Lovette MA, Içten E, Brown DB, Allian A, Flick TG, ... ... Walker SD, et al. Continuous Process Improvement in the Manufacture of Carfilzomib, Part 2: An Improved Process for Synthesis of the Epoxyketone Warhead Organic Process Research & Development. 24: 490-499. DOI: 10.1021/Acs.Oprd.0C00052  0.337
2020 Dornan PK, Anthoine T, Beaver MG, Cheng GC, Cohen DE, Cui S, Lake WE, Langille NF, Lucas SP, Patel J, Powazinik W, Roberts SW, Scardino C, Tucker JL, Spada S, ... ... Walker SD, et al. Continuous Process Improvement in the Manufacture of Carfilzomib, Part 1: Process Understanding and Improvements in the Commercial Route to Prepare the Epoxyketone Warhead Organic Process Research & Development. 24: 481-489. DOI: 10.1021/Acs.Oprd.0C00051  0.318
2019 Caille S, Cui S, Faul MM, Mennen SM, Tedrow JS, Walker SD. Molecular Complexity as a Driver for Chemical Process Innovation in the Pharmaceutical Industry. The Journal of Organic Chemistry. PMID 30916557 DOI: 10.1021/Acs.Joc.9B00735  0.342
2019 Caille S, Allgeier AM, Bernard C, Correll TL, Cosbie A, Crockett RD, Cui S, Faul MM, Hansen KB, Huggins S, Langille N, Mennen SM, Morgan BP, Morrison H, Muci A, ... ... Walker SD, et al. Development of a Factory Process for Omecamtiv Mecarbil, a Novel Cardiac Myosin Activator Organic Process Research & Development. 23: 1558-1567. DOI: 10.1021/Acs.Oprd.9B00200  0.317
2018 Cochran BM, Corbett MT, Correll TL, Fang YQ, Flick TG, Jones SC, Silva Elipe MV, Smith AG, Tucker JL, Vounatsos F, Wells G, Yeung D, Walker SD, Bio MM, Caille S. Development of a Commercial Process to Prepare AMG 232 Using A Green Ozonolysis-Pinnick Tandem Transformation. The Journal of Organic Chemistry. PMID 30557503 DOI: 10.1021/Acs.Joc.8B02390  0.381
2011 Kasparian AJ, Savarin C, Allgeier AM, Walker SD. Selective catalytic hydrogenation of nitro groups in the presence of activated heteroaryl halides. The Journal of Organic Chemistry. 76: 9841-4. PMID 21988595 DOI: 10.1021/Jo2015664  0.362
2011 Caille S, Crockett R, Ranganathan K, Wang X, Woo JC, Walker SD. Catalytic asymmetric synthesis of a tertiary benzylic carbon center via phenol-directed alkene hydrogenation. The Journal of Organic Chemistry. 76: 5198-206. PMID 21630712 DOI: 10.1021/Jo200941R  0.649
2011 Wang X, Guram A, Caille S, Hu J, Preston JP, Ronk M, Walker S. Highly enantioselective hydrogenation of styrenes directed by 2'-hydroxyl groups. Organic Letters. 13: 1881-3. PMID 21384895 DOI: 10.1021/Ol200422P  0.642
2011 Wang X, Guram A, Caille S, Hu J, Preston JP, Ronk M, Walker S. Asymmetric Synthesis of (R)-Tolterodine Synfacts. 2011: 696-696. DOI: 10.1055/S-0030-1260481  0.314
2011 Walker SD, Borths CJ, Divirgilio E, Huang L, Liu P, Morrison H, Sugi K, Tanaka M, Woo JCS, Faul MM. Development of a scalable synthesis of a GPR40 receptor agonist Organic Process Research and Development. 15: 570-580. DOI: 10.1021/Op1003055  0.393
2011 Tan H, Cui S, Gahm K, Luu V, Walker SD. Rational screening approach for classical chiral resolution under thermodynamic equilibrium: A case study of diphenyl-substituted N-methyl-piperazine Organic Process Research and Development. 15: 53-63. DOI: 10.1021/Op1002402  0.339
2010 Cui S, Walker SD, Woo JC, Borths CJ, Mukherjee H, Chen MJ, Faul MM. Practical asymmetric conjugate alkynylation of Meldrum's acid-derived acceptors: access to chiral beta-alkynyl acids. Journal of the American Chemical Society. 132: 436-7. PMID 20020682 DOI: 10.1021/Ja909105S  0.352
2010 Woo JCS, Cui S, Walker SD, Faul MM. Asymmetric syntheses of a GPR40 receptor agonist via diastereoselective and enantioselective conjugate alkynylation Tetrahedron. 66: 4730-4737. DOI: 10.1016/J.Tet.2010.04.019  0.388
2007 Zigterman JL, Woo JC, Walker SD, Tedrow JS, Borths CJ, Bunel EE, Faul MM. Highly selective rhodium-catalyzed conjugate addition reactions of 4-oxobutenamides. The Journal of Organic Chemistry. 72: 8870-6. PMID 17927253 DOI: 10.1021/Jo701682C  0.398
2007 Woo JCS, Walker SD, Faul MM. Preparation and decarboxylative rearrangement of (Z)-enyne esters Tetrahedron Letters. 48: 5679-5682. DOI: 10.1016/J.Tetlet.2007.06.012  0.367
2005 Barder TE, Walker SD, Martinelli JR, Buchwald SL. Catalysts for Suzuki-Miyaura coupling processes: scope and studies of the effect of ligand structure. Journal of the American Chemical Society. 127: 4685-96. PMID 15796535 DOI: 10.1021/Ja042491J  0.385
2004 Walker SD, Barder TE, Martinelli JR, Buchwald SL. A rationally designed universal catalyst for Suzuki-Miyaura coupling processes. Angewandte Chemie (International Ed. in English). 43: 1871-6. PMID 15054800 DOI: 10.1002/Anie.200353615  0.414
2000 Piers E, Walker SD, Armbrust R. A new cycloheptenone annulation method: Use of the bifunctional reagent (Z)-5-iodo-l-tributylstannyIpent-l-ene in organic synthesis Journal of the Chemical Society, Perkin Transactions 1. 635-637. DOI: 10.1039/A909922K  0.564
1999 Piers E, Romero MA, Walker SD. Sequential Anionic 1,3 Ester Shifts and Intramolecular Stille Couplings: A New Protocol for the Concise Assembly of Functionalized Polycyclic Dienes Synlett. 1999: 1082-1084. DOI: 10.1055/S-1999-2771  0.327
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