Phillip A. Schwartz, Ph.D.
Affiliations: | 2006 | University of Wisconsin, Madison, Madison, WI |
Area:
Mechanisms of enzyme and coenzyme action; stereochemistry and mechanisms of phospho- and nucleotidyl transferase action; structure and function of multienzyme complexesGoogle:
"Phillip Schwartz"Mean distance: 8.56 | S | N | B | C | P |
Parents
Sign in to add mentor| Perry A. Frey | grad student | 2006 | UW Madison | |
| (On the mechanism by which monocations activate adenosylcobalamin-dependent dioldehydrase.) | ||||
| Vern L. Schramm | post-doc | Albert Einstein | ||
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Publications
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| Schwartz PA, Vetticatt MJ, Schramm VL. (2011) Transition state analysis of the arsenolytic depyrimidination of thymidine by human thymidine phosphorylase. Biochemistry. 50: 1412-20 |
| Schwartz PA, Vetticatt MJ, Schramm VL. (2010) Transition state analysis of thymidine hydrolysis by human thymidine phosphorylase. Journal of the American Chemical Society. 132: 13425-33 |
| Schwartz PA, Lobrutto R, Reed GH, et al. (2007) Probing interactions from solvent-exchangeable protons and monovalent cations with the 1,2-propanediol-1-yl radical intermediate in the reaction of dioldehydrase. Protein Science : a Publication of the Protein Society. 16: 1157-64 |
| Schwartz PA, Frey PA. (2007) Dioldehydrase: an essential role for potassium ion in the homolytic cleavage of the cobalt-carbon bond in adenosylcobalamin. Biochemistry. 46: 7293-301 |
| Schwartz PA, Frey PA. (2007) 5'-Peroxyadenosine and 5'-peroxyadenosylcobalamin as intermediates in the aerobic photolysis of adenosylcobalamin. Biochemistry. 46: 7284-92 |