Lark J. Perez, Ph.D.

Affiliations: 
2009 Yale University, New Haven, CT 
Area:
Organic Chemistry, Medicinal Chemistry
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"Lark Perez"
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Glenn Christopher Micalizio grad student 2009 Yale
 (Titanium-mediated reductive fragment union processes in complex molecule assembly.)
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Publications

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Capilato JN, Pellegrinelli PJ, Bernard J, et al. (2021) Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives. Organic & Biomolecular Chemistry
Watve S, Barrasso K, Jung SA, et al. (2020) Parallel quorum-sensing system in Vibrio cholerae prevents signal interference inside the host. Plos Pathogens. 16: e1008313
Flockton TR, Schnorbus L, Araujo A, et al. (2019) Inhibition of Biofilm Formation with Surface Modified Polymeric Nanoparticles. Pathogens (Basel, Switzerland). 8
Capilato JN, Philippi SV, Reardon T, et al. (2016) Development of a novel series of non-natural triaryl agonists and antagonists of the Pseudomonas aeruginosa LasR quorum sensing receptor. Bioorganic & Medicinal Chemistry
Wu B, Capilato J, Pham MP, et al. (2016) Lipoxin A4 augments host defense in sepsis and reduces Pseudomonas aeruginosa virulence through quorum sensing inhibition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
O'Brien KT, Noto JG, Nichols-O'Neill L, et al. (2015) Potent Irreversible Inhibitors of LasR Quorum Sensing in Pseudomonas aeruginosa. Acs Medicinal Chemistry Letters. 6: 162-7
Lu HD, Spiegel AC, Hurley A, et al. (2015) Modulating Vibrio cholerae quorum-sensing-controlled communication using autoinducer-loaded nanoparticles. Nano Letters. 15: 2235-41
Werner KM, Perez LJ, Ghosh R, et al. (2014) Caenorhabditis elegans recognizes a bacterial quorum-sensing signal molecule through the AWCON neuron. The Journal of Biological Chemistry. 289: 26566-73
Perez LJ, Karagounis TK, Hurley A, et al. (2014) Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae. Chemical Science (Royal Society of Chemistry : 2010). 5: 151-155
Perez LJ, Ng WL, Marano P, et al. (2012) Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response. Journal of Medicinal Chemistry. 55: 9669-81
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