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Charles E. McKenna

Affiliations: 
University of Southern California, Los Angeles, CA, United States 
Area:
organophosphorus, bioorganic and medicinal chemistry
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"Charles McKenna"
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Parents

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Teddy G. Traylor grad student
Frank H. Westheimer post-doc

Children

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jingyue ju grad student Columbia U
Jennifer Olivero grad student USC
William G. Gutheil grad student 1983-1989
James M. Carrick grad student 2000 USC
Xue-Wei Liu grad student 2000 USC
Patricia I. Bonaz grad student 2002 USC
Ulrika Eriksson grad student 2005 USC
Mong S. Marma grad student 2005 USC
Gregorio V. Sanchez grad student 2006 USC
Jian-Jung Pan grad student 2007 USC
Kanokkarn Saejueng grad student 2008 USC
Thomas G. Upton grad student 2008 USC
Joy L. Bala grad student 2009 USC
Larryn W. Peterson grad student 2009 USC
Brian T. Chamberlain grad student 2012 USC
Ivan S. Krylov grad student 2012 USC
Dana Mustafa grad student 2013 USC
Jorge Osuna grad student 2013 USC
Elisa G. Gutierrez post-doc 2014-2015 USC

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Publications

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Jacobs MR, Olivero JE, Ok Choi H, et al. (2023) Synthesis and anti-cancer potential of potent peripheral MAOA inhibitors designed to limit blood:brain penetration. Bioorganic & Medicinal Chemistry. 92: 117425
Mustafa D, Overhulse JM, Kashemirov BA, et al. (2023) Microwave-Accelerated McKenna Synthesis of Phosphonic Acids: An Investigation. Molecules (Basel, Switzerland). 28
Haratipour P, Minard C, Nakhjiri M, et al. (2020) Completing the β,γ-CXY-dNTP Stereochemical Probe Toolkit: Synthetic Access to the dCTP Diastereomers and P and F NMR Correlations with Absolute Configurations. The Journal of Organic Chemistry
Batra VK, Alnajjar KS, Sweasy JB, et al. (2020) Revealing an internal stabilization deficiency in the DNA polymerase β K289M cancer variant through combined use of chemical biology and X-ray crystallography. Biochemistry
Haratipour P, Minard C, Nakhjiri M, et al. (2019) New Chirally Modified Bisphosphonates for Synthesis of Individual Beta,Gamma-CHX-Deoxynucleotide Diastereomers. Phosphorus, Sulfur, and Silicon and the Related Elements. 194: 329-330
Alnajjar KS, Krylov IS, Negahbani A, et al. (2019) A pre-catalytic non-covalent step governs DNA polymerase β fidelity. Nucleic Acids Research
Duro MVV, Alnajjar KS, Sweasy JB, et al. (2019) Synthesis of -Formylphenylphosphonic Acids as Covalent Probes of Active Site Lysines. Phosphorus, Sulfur, and Silicon and the Related Elements. 194: 313-314
Oertell K, Florian J, Haratipour P, et al. (2019) A Transition-State Perspective on Y-Family DNA Polymerase η Fidelity in Comparison with X-Family DNA Polymerases λ and β. Biochemistry
Oertell K, Kashemirov BA, Negahbani A, et al. (2018) Probing DNA base-dependent leaving group kinetic effects on the DNA polymerase transition state. Biochemistry
Batra VK, Oertell K, Beard WA, et al. (2018) Mapping functional substrate-enzyme interactions in the pol β active site through chemical biology: Structural responses to acidity modification of incoming dNTPs. Biochemistry
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