Kittichoat Tiyanont, Ph.D.

Affiliations: 
2007 Princeton University, Princeton, NJ 
Area:
Chemical biology, enzymology, antibiotics, glycosyltransferases, inhibitors
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"Kittichoat Tiyanont"
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Suzanne Walker grad student 2007 Princeton
 (Imaging bacterial peptidoglycan biosynthesis with fluorescent antibiotics.)
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Publications

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Xu X, Choi SH, Hu T, et al. (2015) Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region. Structure (London, England : 1993). 23: 1227-35
Gordon WR, Zimmerman B, He L, et al. (2015) Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch. Developmental Cell. 33: 729-36
Habets RA, Groot AJ, Yahyanejad S, et al. (2015) Human NOTCH2 Is Resistant to Ligand-independent Activation by Metalloprotease Adam17. The Journal of Biological Chemistry. 290: 14705-16
Tiyanont K, Wales TE, Siebel CW, et al. (2013) Insights into Notch3 activation and inhibition mediated by antibodies directed against its negative regulatory region. Journal of Molecular Biology. 425: 3192-204
Tiyanont K, Wales TE, Aste-Amezaga M, et al. (2011) Evidence for increased exposure of the Notch1 metalloprotease cleavage site upon conversion to an activated conformation. Structure (London, England : 1993). 19: 546-54
Aste-Amézaga M, Zhang N, Lineberger JE, et al. (2010) Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. Plos One. 5: e9094
Fang X, Tiyanont K, Zhang Y, et al. (2006) The mechanism of action of ramoplanin and enduracidin. Molecular Biosystems. 2: 69-76
Tiyanont K, Doan T, Lazarus MB, et al. (2006) Imaging peptidoglycan biosynthesis in Bacillus subtilis with fluorescent antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 103: 11033-8
Hu Y, Helm JS, Chen L, et al. (2004) Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening. Chemistry & Biology. 11: 703-11
Whyte A, Yang ZC, Tiyanont K, et al. (1999) Reptilian chemistry: characterization of dianeackerone, a secretory product from a crocodile. Proceedings of the National Academy of Sciences of the United States of America. 96: 12246-50
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