Edwin H. Rydberg, Ph.D.

Affiliations: 
2000 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
enzyme mechanisms, protein structure/function relationships, enzyme inhibitor design/synthesis and protein engineering
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"Edwin Rydberg"
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Parents

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Stephen G. Withers grad student 2000 UBC
 (Mechanistic studies on human pancreatic alpha-amylase.)
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Publications

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Li C, Rydberg E, Williams L, et al. (2008) Mechanistic role of the catalytic residue D300 in human pancreatic alpha-amylase Acta Crystallographica Section a Foundations of Crystallography. 64: C263-C263
Rydberg EH, Brumshtein B, Greenblatt HM, et al. (2006) Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge. Journal of Medicinal Chemistry. 49: 5491-500
Zeev-Ben-Mordehai T, Rydberg EH, Solomon A, et al. (2003) The intracellular domain of the Drosophila cholinesterase-like neural adhesion protein, gliotactin, is natively unfolded. Proteins. 53: 758-67
Rydberg EH, Li C, Maurus R, et al. (2002) Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids. Biochemistry. 41: 4492-502
Brayer GD, Sidhu G, Maurus R, et al. (2000) Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques. Biochemistry. 39: 4778-91
Rydberg EH, Sidhu G, Vo HC, et al. (1999) Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris. Protein Science : a Publication of the Protein Society. 8: 635-43
Rydberg EH, Overall CM, Withers SG. (1997) Mechanistic studies of human pancreatic o-amylase Faseb Journal. 11: A1311
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