Charles A. Boswell, Ph.D.

Affiliations: 
2004 Washington University, Saint Louis, St. Louis, MO 
Area:
PET agents for cancer imaging
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Parents

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Carolyn J. Anderson grad student 2004 Washington University
 (Copper-64-labeled tetraazamacrocyclic complexes as components of radiopharmaceuticals: Metabolism, characterization, and mechanisms of metal dissociation.)
Sean B. Joseph research scientist 2013-2016 Genentech, Inc.
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Publications

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Nazarova L, Rafidi H, Mandikian D, et al. (2020) Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-Length Antibodies. Molecular Cancer Therapeutics
Boswell CA, Yadav DB, Mundo EE, et al. (2019) Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer. Oncotarget. 10: 6234-6244
Famili A, Crowell S, Loyet KM, et al. (2019) Hyaluronic Acid-Antibody Fragment Bioconjugates for Extended Ocular Pharmacokinetics. Bioconjugate Chemistry
Lombana TN, Rajan S, Zorn JA, et al. (2019) Production, characterization, and half-life extension of polymeric IgA molecules in mice. Mabs
Mandikian D, Figueroa I, Oldendorp A, et al. (2018) Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology. The Aaps Journal. 20: 107
Mandikian D, Rafidi H, Adhikari P, et al. (2018) Site-specific conjugation allows modulation of click reaction stoichiometry for pretargeted SPECT imaging. Mabs
Dominguez SL, Hegde GV, Hanson JE, et al. (2018) Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice. Scientific Reports. 8: 8239
Mandikian D, Takahashi N, Lo AA, et al. (2018) Relative Target Affinities of T Cell-Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model. Molecular Cancer Therapeutics
Rajan S, Mandikian D, Baruch A, et al. (2017) Preclinical pharmacokinetic characterization of an adipose tissue-targeting monoclonal antibody in obese and non-obese animals. Mabs. 0
Deng R, Bumbaca D, Pastuskovas CV, et al. (2016) Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor. Mabs. 1-11
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