Charles A. Boswell, Ph.D.

Affiliations: 
2004 Washington University, Saint Louis, St. Louis, MO 
Area:
PET agents for cancer imaging
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Parents

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Carolyn J. Anderson grad student 2004 Washington University
 (Copper-64-labeled tetraazamacrocyclic complexes as components of radiopharmaceuticals: Metabolism, characterization, and mechanisms of metal dissociation.)
Sean B. Joseph research scientist 2013-2016 Genentech, Inc.
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Publications

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Mandikian D, Figueroa I, Oldendorp A, et al. (2018) Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology. The Aaps Journal. 20: 107
Mandikian D, Takahashi N, Lo AA, et al. (2018) Relative Target Affinities of T Cell-Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model. Molecular Cancer Therapeutics
Dickmann LJ, Yip V, Li C, et al. (2015) Evaluation of Fluorophotometry to Assess the Vitreal Pharmacokinetics of Protein Therapeutics. Investigative Ophthalmology & Visual Science. 56: 6991-9
Bumbaca Yadav D, Sharma VK, Boswell CA, et al. (2015) Evaluating the use of antibody variable region (Fv) charge as a risk assessment tool for predicting typical cynomolgus monkey pharmacokinetics. The Journal of Biological Chemistry
Bumbaca D, Boswell CA, Mundo EE, et al. (2011) Abstract 4588: Tumor distribution of anti-neuropilin-1 is affected by antibody dose level in a tumor xenograft mouse model Cancer Research. 71: 4588-4588
Bumbaca D, Boswell CA, Xiang H, et al. (2010) Abstract 696: Anti-NRP1 tumor uptake is impacted by normal tissue sinks in a tumor bearing mouse model Cancer Research. 70: 696-696
Shen X, Boswell CA, Wong EH, et al. (2006) Investigation of copper-azamacrocyclic complexes by high-performance liquid chromatography. Biomedical Chromatography : Bmc. 20: 37-47
Boswell CA, McQuade P, Weisman GR, et al. (2005) Optimization of labeling and metabolite analysis of copper-64-labeled azamacrocyclic chelators by radio-LC-MS. Nuclear Medicine and Biology. 32: 29-38
Woodin KS, Heroux KJ, Boswell CA, et al. (2005) Kinetic inertness and electrochemical behavior of copper(II) tetraazamacrocyclic complexes: Possible implications for in vivo stability European Journal of Inorganic Chemistry. 4829-4833
Boswell CA, Sun X, Niu W, et al. (2004) Comparative in vivo stability of copper-64-labeled cross-bridged and conventional tetraazamacrocyclic complexes. Journal of Medicinal Chemistry. 47: 1465-74
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