Rob Leurs

Medicinal Chemistry Vrije Universiteit Amsterdam, Amsterdam, Netherlands 
GPCRs, Histamine receptors, Chemokine receptors
"Rob Leurs"
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Egyed A, Kelemen ÁA, Vass M, et al. (2021) Controlling the selectivity of aminergic GPCR ligands from the extracellular vestibule. Bioorganic Chemistry. 111: 104832
de Heuvel E, Kooistra AJ, Edink E, et al. (2020) Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening. Frontiers in Chemistry. 8: 608030
Munday JC, Kunz S, Kalejaiye TD, et al. (2020) Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages. Plos Neglected Tropical Diseases. 14: e0008447
Sijm M, Sterk GJ, Caljon G, et al. (2020) Structure activity relationship of phenylpyrazolones against Trypanosoma cruzi. Chemmedchem
G Salado I, Singh AK, Moreno-Cinos C, et al. (2020) Lead optimization of phthalazinone phosphodiesterase inhibitors as novel antitrypanosomal compounds. Journal of Medicinal Chemistry
Kanev GK, de Graaf C, de Esch IJP, et al. (2019) The Landscape of Atypical and Eukaryotic Protein Kinases. Trends in Pharmacological Sciences. 40: 818-832
Adlere I, Caspar B, Arimont M, et al. (2019) Modulators of CXCR4 and CXCR7/ACKR3 function. Molecular Pharmacology
van Senten JR, Bebelman MP, Fan TS, et al. (2019) The human cytomegalovirus-encoded G protein-coupled receptor UL33 exhibits oncomodulatory properties. The Journal of Biological Chemistry
de Heuvel E, Singh AK, Boronat P, et al. (2019) Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2). Bioorganic & Medicinal Chemistry
Sebastián-Pérez V, Schroeder S, Munday JC, et al. (2019) Discovery of novel PDE4A inhibitors as potential agents against schistosomiasis. Future Medicinal Chemistry
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