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Rob Leurs

Affiliations: 
Medicinal Chemistry Vrije Universiteit Amsterdam, Amsterdam, Netherlands 
Area:
GPCRs, Histamine receptors, Chemokine receptors
Website:
http://www.chem.vu.nl/en/research/division-of-medicinal-chemistry/index.asp
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"Rob Leurs"
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Parents

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Henk Timmerman grad student Free University of Amsterdam

Children

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Martine Joyce Smit grad student 1995 VU Amsterdam
Richard M. Van Rijn grad student 2002-2006 VU Amsterdam (Neurotree)
Kamonchanok Sansuk grad student 2004-2008 Vrije Universiteit, Amsterdam, Sheffield (Neurotree)

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Publications

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Egyed A, Kelemen ÁA, Vass M, et al. (2021) Controlling the selectivity of aminergic GPCR ligands from the extracellular vestibule. Bioorganic Chemistry. 111: 104832
de Heuvel E, Kooistra AJ, Edink E, et al. (2020) Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening. Frontiers in Chemistry. 8: 608030
Munday JC, Kunz S, Kalejaiye TD, et al. (2020) Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages. Plos Neglected Tropical Diseases. 14: e0008447
Sijm M, Sterk GJ, Caljon G, et al. (2020) Structure activity relationship of phenylpyrazolones against Trypanosoma cruzi. Chemmedchem
G Salado I, Singh AK, Moreno-Cinos C, et al. (2020) Lead optimization of phthalazinone phosphodiesterase inhibitors as novel antitrypanosomal compounds. Journal of Medicinal Chemistry
Kanev GK, de Graaf C, de Esch IJP, et al. (2019) The Landscape of Atypical and Eukaryotic Protein Kinases. Trends in Pharmacological Sciences. 40: 818-832
Adlere I, Caspar B, Arimont M, et al. (2019) Modulators of CXCR4 and CXCR7/ACKR3 function. Molecular Pharmacology
van Senten JR, Bebelman MP, Fan TS, et al. (2019) The human cytomegalovirus-encoded G protein-coupled receptor UL33 exhibits oncomodulatory properties. The Journal of Biological Chemistry
de Heuvel E, Singh AK, Boronat P, et al. (2019) Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2). Bioorganic & Medicinal Chemistry
Sebastián-Pérez V, Schroeder S, Munday JC, et al. (2019) Discovery of novel PDE4A inhibitors as potential agents against schistosomiasis. Future Medicinal Chemistry
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