Rob Leurs
Affiliations: | Medicinal Chemistry | Vrije Universiteit Amsterdam, Amsterdam, Netherlands |
Area:
GPCRs, Histamine receptors, Chemokine receptorsWebsite:
http://www.chem.vu.nl/en/research/division-of-medicinal-chemistry/index.aspGoogle:
"Rob Leurs"Mean distance: 13.53 | S | N | B | C | P |
Children
Sign in to add trainee| Martine Joyce Smit | grad student | 1995 | VU Amsterdam |
| Richard M. Van Rijn | grad student | 2002-2006 | VU Amsterdam (Neurotree) |
| Kamonchanok Sansuk | grad student | 2004-2008 | Vrije Universiteit, Amsterdam, Sheffield (Neurotree) |
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Publications
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| Rahman SN, McNaught-Flores DA, Huppelschoten Y, et al. (2023) Structural and Molecular Determinants for Isoform Bias at Human Histamine H Receptor Isoforms. Acs Chemical Neuroscience |
| Wágner G, Mocking TAM, Ma X, et al. (2022) SAR exploration of the non-imidazole histamine H receptor ligand ZEL-H16 reveals potent inverse agonism. Archiv Der Pharmazie. e2200451 |
| Ma X, Gao M, Vischer HF, et al. (2022) A NanoBRET-Based HR Conformational Biosensor to Study Real-Time H Receptor Pharmacology in Cell Membranes and Living Cells. International Journal of Molecular Sciences. 23 |
| Zheng Y, Wágner G, Hauwert N, et al. (2022) New Chemical Biology Tools for the Histamine Receptor Family. Current Topics in Behavioral Neurosciences |
| Kok ZY, Stoddart LA, Mistry SJ, et al. (2022) Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H Receptor. Journal of Medicinal Chemistry. 65: 8258-8288 |
| Verweij EWE, Bosma R, Gao M, et al. (2022) BRET-Based Biosensors to Measure Agonist Efficacies in Histamine H Receptor-Mediated G Protein Activation, Signaling and Interactions with GRKs and β-Arrestins. International Journal of Molecular Sciences. 23 |
| Ma X, Verweij EWE, Siderius M, et al. (2021) Identification of TSPAN4 as Novel Histamine H Receptor Interactor. Biomolecules. 11 |
| Ma X, Leurs R, Vischer HF. (2021) NanoLuc-Based Methods to Measure β-Arrestin2 Recruitment to G Protein-Coupled Receptors. Methods in Molecular Biology (Clifton, N.J.). 2268: 233-248 |
| Wang Z, Bosma R, Kuhne S, et al. (2021) Exploring the Effect of Cyclization of Histamine H Receptor Antagonists on Ligand Binding Kinetics. Acs Omega. 6: 12755-12768 |
| Ma X, Segura MA, Zarzycka B, et al. (2021) Analysis of Missense Variants in the Human Histamine Receptor Family Reveals Increased Constitutive Activity of E410K Variant in the Histamine H Receptor. International Journal of Molecular Sciences. 22 |