Rob Leurs
Affiliations: | Medicinal Chemistry | Vrije Universiteit Amsterdam, Amsterdam, Netherlands |
Area:
GPCRs, Histamine receptors, Chemokine receptorsWebsite:
http://www.chem.vu.nl/en/research/division-of-medicinal-chemistry/index.aspGoogle:
"Rob Leurs"Mean distance: 13.53
Children
Sign in to add trainee| Martine Joyce Smit | grad student | 1995 | VU Amsterdam |
| Richard M. Van Rijn | grad student | 2002-2006 | VU Amsterdam (Neurotree) |
| Kamonchanok Sansuk | grad student | 2004-2008 | Vrije Universiteit, Amsterdam, Sheffield (Neurotree) |
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Publications
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| Stéen EJL, Tousiaki EN, Kingston L, et al. (2025) Characterization of [H]AZ12464237 as a high affinity, non-nucleotide antagonist radioligand for the P2Y receptor. Biochemical Pharmacology. 116900 |
| Saha S, Sano FK, Sharma S, et al. (2025) Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system. Nature Communications. 16: 3047 |
| Bérenger S, Adamska JM, Deflorian F, et al. (2025) Design, Synthesis and Pharmacological Characterization of the First Photoswitchable Small-Molecule Agonist for the Atypical Chemokine Receptor 3. Acs Omega. 10: 8675-8686 |
| Kuhne S, Bosma R, Kooistra AJ, et al. (2024) Probing the Histamine H Receptor Binding Site to Explore Ligand Binding Kinetics. Journal of Medicinal Chemistry |
| McNaught-Flores DA, Chen YC, Arias-Montaño JA, et al. (2024) Pharmacological characterization of the zebrafish Hrh2a histamine H receptor. European Journal of Pharmacology. 981: 176870 |
| Gao M, Ooms JF, Leurs R, et al. (2024) Histamine H Receptor Isoforms: Insights from Alternative Splicing to Functional Complexity. Biomolecules. 14 |
| Otun O, Aljamous C, Del Nero E, et al. (2024) Conformational dynamics underlying atypical chemokine receptor 3 activation. Proceedings of the National Academy of Sciences of the United States of America. 121: e2404000121 |
| Adamska JM, Leftheriotis S, Bosma R, et al. (2024) Multiplex Detection of Fluorescent Chemokine Binding to CXC Chemokine Receptors by NanoBRET. International Journal of Molecular Sciences. 25 |
| Zheng Y, Gao M, Wijtmans M, et al. (2024) Synthesis and Pharmacological Characterization of New Photocaged Agonists for Histamine H and H Receptors. Pharmaceuticals (Basel, Switzerland). 17 |
| Xia R, Shi S, Xu Z, et al. (2024) Structural basis of ligand recognition and design of antihistamines targeting histamine H receptor. Nature Communications. 15: 2493 |