Yafei Huang, Ph.D.

Affiliations: 
2002 University of Kansas, Lawrence, KS, United States 
Area:
Molecular Biology, Biochemistry
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"Yafei Huang"
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Fusao Takusagawa grad student 2002 University of Kansas
 (Crystallographic studies of two enzymes involved in the methyl cycle: Glycine N-methyltransferase (GNMT) and S-adenosylhomocysteine hydrolase (AdoHcyase).)
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Publications

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Fu TM, Almqvist J, Liang YH, et al. (2011) Crystal structures of cobalamin-independent methionine synthase (MetE) from Streptococcus mutans: a dynamic zinc-inversion model. Journal of Molecular Biology. 412: 688-97
Lemieux MJ, Huang Y, Wang da N. (2005) Crystal structure and mechanism of GlpT, the glycerol-3-phosphate transporter from E. coli. Journal of Electron Microscopy. 54: i43-6
Lemieux MJ, Huang Y, Wang DN. (2004) Glycerol-3-phosphate transporter of Escherichia coli: structure, function and regulation. Research in Microbiology. 155: 623-9
Lemieux MJ, Huang Y, Wang DN. (2004) The structural basis of substrate translocation by the Escherichia coli glycerol-3-phosphate transporter: a member of the major facilitator superfamily. Current Opinion in Structural Biology. 14: 405-12
Huang Y, Lemieux MJ, Song J, et al. (2003) Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli. Science (New York, N.Y.). 301: 616-20
Takata Y, Huang Y, Komoto J, et al. (2003) Catalytic mechanism of glycine N-methyltransferase. Biochemistry. 42: 8394-402
Takata Y, Huang Y, Komoto J, et al. (2003) Catalytic Mechanism of GlycineN-Methyltransferase, Biochemistry. 42: 10874-10874
Komoto J, Huang Y, Takata Y, et al. (2002) Crystal structure of guanidinoacetate methyltransferase from rat liver: a model structure of protein arginine methyltransferase. Journal of Molecular Biology. 320: 223-35
Takata Y, Yamada T, Huang Y, et al. (2002) Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190. The Journal of Biological Chemistry. 277: 22670-6
Huang Y, Komoto J, Takata Y, et al. (2002) Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine. The Journal of Biological Chemistry. 277: 7477-82
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