Fusao Takusagawa

University of Kansas, Lawrence, KS, United States 
Molecular Biology, Biochemistry
"Fusao Takusagawa"
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Gomi T, Takusagawa F, Nishizawa M, et al. (2008) Cloning, bacterial expression, and unique structure of adenosylhomocysteine hydrolase-like protein 1, or inositol 1,4,5-triphosphate receptor-binding protein from mouse kidney. Biochimica Et Biophysica Acta. 1784: 1786-94
Yamada T, Komoto J, Kasuya T, et al. (2008) A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies. Biochimica Et Biophysica Acta. 1780: 809-18
Yamada T, Takusagawa F. (2007) PGH2 degradation pathway catalyzed by GSH-heme complex bound microsomal prostaglandin E2 synthase type 2: the first example of a dual-function enzyme. Biochemistry. 46: 8414-24
Saiki K, Yamada T, Takusagawa F, et al. (2007) [Structure, function, and stability of cytolethal distending toxin]. Seikagaku. the Journal of Japanese Biochemical Society. 79: 350-4
Yamada T, Komoto J, Lou K, et al. (2007) Structure and function of eritadenine and its 3-deaza analogues: potent inhibitors of S-adenosylhomocysteine hydrolase and hypocholesterolemic agents. Biochemical Pharmacology. 73: 981-9
Ogawa H, Gomi T, Nishizawa M, et al. (2006) Enzymatic and biochemical properties of a novel human serine dehydratase isoform. Biochimica Et Biophysica Acta. 1764: 961-71
Komoto J, Yamada T, Watanabe K, et al. (2006) Prostaglandin F2alpha formation from prostaglandin H2 by prostaglandin F synthase (PGFS): crystal structure of PGFS containing bimatoprost. Biochemistry. 45: 1987-96
Yamada T, Komoto J, Saiki K, et al. (2006) Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans. Protein Science : a Publication of the Protein Society. 15: 362-72
Yamada T, Takata Y, Komoto J, et al. (2005) Catalytic mechanism of S-adenosylhomocysteine hydrolase: roles of His 54, Asp130, Glu155, Lys185, and Aspl89. The International Journal of Biochemistry & Cell Biology. 37: 2417-35
Yamada T, Komoto J, Watanabe K, et al. (2005) Crystal structure and possible catalytic mechanism of microsomal prostaglandin E synthase type 2 (mPGES-2). Journal of Molecular Biology. 348: 1163-76
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