David N. Frick, PH.D.

Affiliations: 
2000-2010 Biochemistry and Molecular Biology New York Medical College, New York, NY, United States 
 2010- Chemistry & BIOCHEMISTRY University of Wisconsin, Milwaukee 
Area:
Biochemistry, Molecular Biology, Virology Biology
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"David Frick"
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Cross-listing: Cell Biology Tree

Parents

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Maurice J. Bessman grad student 1990-1996 (Physics Tree)
Charles C. Richardson post-doc

Children

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Craig A. Belon grad student 2010 New York Medical College (Cell Biology Tree)

Collaborators

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Karyn M. Frick collaborator UW-Milwaukee (Neurotree)
Nemanja Vuksanovic collaborator
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Publications

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Belayet JB, Beamish S, Rahaman M, et al. (2022) Development of a Novel, Small-Molecule Brain-Penetrant Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice. Journal of Medicinal Chemistry
Virdi RS, Bavisotto RV, Hopper NC, et al. (2020) Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3. Slas Discovery : Advancing Life Sciences R & D. 2472555220960428
Frick DN, Virdi RS, Vuksanovic N, et al. (2020) Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3. Biochemistry
Ray A, Frick DN. (2020) Fluorescent probe displacement assays reveal unique nucleic acid binding properties of human nudix enzymes. Analytical Biochemistry. 595: 113622
Corby MJ, Raicu V, Frick DN. (2018) New Techniques to Study Intracellular Receptors in Living Cells: Insights Into RIG-I-Like Receptor Signaling. Advances in Experimental Medicine and Biology
Yerukhimovich MM, Marohnic CC, Frick DN. (2018) Role of the Conserved DECH-box Cysteine in Coupling Hepatitis C Virus Helicase-catalyzed ATP hydrolysis to RNA Unwinding. Biochemistry
Corby MJ, Stoneman MR, Biener G, et al. (2017) Quantitative Micro-Spectroscopic Imaging Reveals Viral and Cellular RNA Helicase Interactions in Live Cells. The Journal of Biological Chemistry
Bassetto M, Leyssen P, Neyts J, et al. (2017) Shape-based virtual screening, synthesis and evaluation of novel pyrrolone derivatives as antiviral agents against HCV. Bioorganic & Medicinal Chemistry Letters
Bassetto M, Ferla S, Leyssen P, et al. (2016) Novel symmetrical phenylenediamines as potential anti-hepatitis C virus agents. Antiviral Chemistry & Chemotherapy
Bassetto M, Leyssen P, Neyts J, et al. (2016) In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase. European Journal of Medicinal Chemistry. 125: 1115-1131
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