Lawrence P. McIntosh

University of British Columbia, Vancouver, Vancouver, BC, Canada 
Molecular Biology, Biochemistry
"Lawrence McIntosh"
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Perez-Borrajero C, Lin CS, Okon M, et al. (2018) The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. Journal of Molecular Biology
Brockerman JA, Okon M, Withers SG, et al. (2018) The pK values of the catalytic residues in the retaining glycoside hydrolase T26H mutant of T4 lysozyme. Protein Science : a Publication of the Protein Society
Bergeron JRC, Brockerman JA, Vuckovic M, et al. (2018) Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK. Protein Science : a Publication of the Protein Society
Koetzler MP, Robinson K, Chen HM, et al. (2018) Modulating the nucleophile of a glycoside hydrolase through site-specific incorporation of fluoroglutamic acids. Journal of the American Chemical Society
Heinkel F, Shen L, Richard-Greenblatt M, et al. (2018) Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacteriumtuberculosis ABC Transporter Rv1747. Structure (London, England : 1993)
Gardill BR, Rivera-Acevedo RE, Tung CC, et al. (2018) The voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations. Scientific Reports. 8: 4483
Currie SL, Doane JJ, Evans KS, et al. (2017) ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain. Journal of Molecular Biology
Currie SL, Lau DK, Doane JJ, et al. (2017) Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Research
Desjardins G, Okon M, Graves BJ, et al. (2016) Conformational dynamics and the binding of specific and non-specific DNA by the autoinhibited transcription factor Ets-1. Biochemistry
Perez-Borrajero C, Okon M, McIntosh LP. (2016) Structural and dynamics studies of Pax5 reveal asymmetry in stability and DNA binding by the Paired domain. Journal of Molecular Biology
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