Mark A. Lemmon

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Medical Biophysics, Molecular Biology, Biochemistry
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Children

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Courtney M. Smith grad student 2015- Yale
Joshua B. Sheetz grad student 2016- Yale
Chun Hu grad student 2017- Yale (Neurotree)
Mitchell B. Berger grad student 2004 Penn
Jong W. Yu grad student 2004 Penn
Mark A. Baumeister grad student 2005 Penn
Kelley A. Bethoney grad student 2008 Penn
Daryl E. Klein grad student 2008 Penn
Katarina Moravcevic grad student 2010 Penn
Scott C. Bresler grad student 2011 Penn
Fumin Shi grad student 2012 Penn
Krishna C. Mudumbi post-doc 2018- Yale (Neurotree)

Collaborators

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David Cowburn collaborator
David J. Riese collaborator Yale
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Publications

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Patil K, Jordan EJ, Park JH, et al. (2021) Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation. Proceedings of the National Academy of Sciences of the United States of America. 118
Wolpaw AJ, Bayliss R, Büchel G, et al. (2021) Drugging the 'undruggable' MYCN oncogenic transcription factor: Overcoming previous obstacles to impact childhood cancers. Cancer Research
Artim SC, Kiyatkin A, Lemmon MA. (2020) Comparison of tyrosine kinase domain properties for the neurotrophin receptors TrkA and TrkB. The Biochemical Journal
Kiyatkin A, van Alderwerelt van Rosenburgh IK, Klein DE, et al. (2020) Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics. Science Signaling. 13
Sheetz JB, Mathea S, Karvonen H, et al. (2020) Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Molecular Cell
Ferguson KM, Hu C, Lemmon MA. (2020) Insulin and EGF receptor family members share parallel activation mechanisms. Protein Science : a Publication of the Protein Society
Starrett JH, Guernet AA, Cuomo ME, et al. (2020) Drug sensitivity and allele-specificity of first-line osimertinib resistance EGFR mutations. Cancer Research
Baro M, Lopez Sambrooks C, Burtness BA, et al. (2019) Neuregulin Signaling is a Mechanism of Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma. Molecular Cancer Therapeutics
Truini A, Starrett JH, Stewart TF, et al. (2019) The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Jordan EJ, Patil K, Suresh K, et al. (2019) Computational algorithms for in silico profiling of activating mutations in cancer. Cellular and Molecular Life Sciences : Cmls
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