Robert V. Stahelin, Ph.D.

Affiliations: 
1998-2006 Chemistry University of Illinois at Chicago, Chicago, IL, United States 
 2006-2017 Chemistry and Biochemistry University of Notre Dame, Notre Dame, IN, United States 
 2006-2017 Biochemistry and Molecular Biology Indiana University School of Medicine-South Bend 
 2017- Medicinal Chemistry and Molecular Biology Purdue University, West Lafayette, IN, United States 
Area:
Biochemistry, General Biophysics, Cell Biology, Virology
Website:
https://thestahelinlab.weebly.com/
Google:
"Stahelin RV"
Bio:

Rob received his PhD in chemistry from the University of Illinois-Chicago, studying the structural basis of lipid-protein interactions. During postdoctoral work at the University of Illinois-Chicago, he investigated the mechanisms with which bioactive lipid signals recruit peripheral proteins in cell signaling and membrane trafficking. Rob moved to South Bend, IN in 2006 to work as an Assistant Professor in Biochemistry and Molecular Biology at Indiana University School of Medicine-South Bend (IUSM-SB) and as an Adjunct Assistant Professor in Chemistry and Biochemistry at the University of Notre Dame. In 2012 he was promoted to Associate Professor and in 2013 was named an IUSM Showalter Scholar. In 2015, Rob was named to the endowed professorship position, Navari Family Scholar, at IUSM-SB. In 2017, Rob moved his lab to Purdue University being appointed the Retter Professor of Pharmacy in the Borch Department of Medicinal Chemistry and Molecular Pharmacology.

Mean distance: (not calculated yet)
 

Parents

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Wonhwa Cho grad student 2003 University of Illinois, Chicago
 (Driving forces for the subcellular localization of peripheral proteins.)

Children

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Hannah Woods grad student 2021-
Elijah Bass grad student 2022- Purdue
Barsha Bhowal grad student 2022- Purdue
Hyun Kim grad student 2023- Purdue
Rokaia Sultana grad student 2023- Purdue
Imrul Hasan grad student 2024- Purdue
Emmanuel Adu-Gyamfi grad student 2008-2013 Notre Dame
Hui Yu grad student 2008-2014 Notre Dame
Jordan L. Scott grad student 2009-2014 Notre Dame
Katherine E. Ward grad student 2009-2014 Notre Dame
Kristen A. Johnson grad student 2013-2017 Notre Dame
Kathryn Del Vecchio grad student 2012-2018 Notre Dame
Carolyn M. Shirey grad student 2013-2018 Notre Dame
Kaveesha J. Wijesinghe grad student 2013-2018 Notre Dame
Mark E. Fraser grad student 2015-2019 Notre Dame
Monica L. Husby grad student 2015-2020 Purdue
Caroline B. Plescia grad student 2017-2022 Purdue
Emily A. David grad student 2018-2023 Purdue
Balindile Motsa grad student 2019-2024 Purdue
Roopashi Saxena grad student 2019-2024 Purdue
Christopher Sudhahar Gunasekaran post-doc 2007-2013 Indiana University of School of Medicine- South Bend
Smita P. Soni post-doc 2010-2015 Indiana University School of Medicine-South Bend (Physics Tree)
Yuan Su post-doc 2018-2021 Purdue
Ranjan Sengupta post-doc 2018-2022 Purdue (Cell & Gene Therapy Tree)
Dhabaleswar Patra post-doc 2019-2022 Purdue
Souad Amiar post-doc 2017-2023 Purdue
BETA: Related publications

Publications

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Sanford LM, Keiser P, Fujii N, et al. (2024) Evaluation of potency and metabolic stability of diphyllin-derived Vacuolar-ATPase inhibitors. European Journal of Medicinal Chemistry. 275: 116537
Dutta M, Su Y, Plescia CB, et al. (2024) The SARS-CoV-2 nucleoprotein associates with anionic lipid membranes. The Journal of Biological Chemistry. 107456
Narkhede Y, Saxena R, Sharma T, et al. (2024) Computational and experimental identification of keystone interactions in Ebola virus matrix protein VP40 dimer formation. Protein Science : a Publication of the Protein Society. 33: e4978
Motsa BB, Sharma T, Ciofi M, et al. (2024) Minor electrostatic changes robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles. The Journal of Biological Chemistry. 107213
Liu X, Husby M, Stahelin RV, et al. (2024) Evaluation of fendiline treatment in VP40 system with nucleation-elongation process: a computational model of Ebola virus matrix protein assembly. Microbiology Spectrum. e0309823
Cioffi MD, Husby ML, Gerstman BS, et al. (2024) Role of phosphatidic acid lipids on plasma membrane association of the Ebola virus matrix protein VP40. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1869: 159464
Motsa BB, Sharma T, Chapagain PP, et al. (2024) Minor changes in electrostatics robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles. Biorxiv : the Preprint Server For Biology
Johnson KA, Budicini MR, Bhattarai N, et al. (2024) PI(4,5)P binding sites in the Ebola virus matrix protein VP40 modulate assembly and budding. Journal of Lipid Research. 100512
Dutta M, Su Y, Voth GA, et al. (2023) The SARS-CoV-2 nucleoprotein associates with anionic lipid membranes. Biorxiv : the Preprint Server For Biology
Liu X, Husby M, Stahelin RV, et al. (2023) Evaluation of Fendiline Treatment in VP40 System with Nucleation-Elongation Process: A Computational Model of Ebola Virus Matrix Protein Assembly. Biorxiv : the Preprint Server For Biology
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