Leemor Joshua-Tor

Affiliations: 
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 
 Howard Hughes Medical Institute, Chevy Chase, MD, United States 
Area:
Structural biology, Nucleic acid regulation, RNAi, Molecular recognition, X-ray crystallography
Website:
http://joshua-torlab.labsites.cshl.edu/
Google:
"Leemor Joshua-Tor"
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Parents

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Joel L. Sussman grad student 1987-1991 Weizmann Institute
 (Three-dimensional structures of bulge-containinig DNA fragments)
Douglas C. Rees post-doc Caltech

Children

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Edward C Twomey research assistant 2012-2012 CSHL
Troy E. Messick grad student 2002 SUNY Stony Brook
Anitra S. Auster grad student 2003 SUNY Stony Brook
Canan Kuscu grad student 2013 SUNY Stony Brook
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Publications

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Jaremko MJ, On KF, Thomas DR, et al. (2020) The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures. Elife. 9
Ando Y, Elkayam E, McPherson RL, et al. (2019) ELTA: Enzymatic Labeling of Terminal ADP-Ribose. Molecular Cell
On KF, Jaremko M, Stillman B, et al. (2018) A structural view of the initiators for chromosome replication. Current Opinion in Structural Biology. 53: 131-139
Zhang T, Wu YC, Mullane P, et al. (2018) FUS Regulates Activity of MicroRNA-Mediated Gene Silencing. Molecular Cell. 69: 787-801.e8
Li J, Wu C, Wang W, et al. (2018) Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference. Proceedings of the National Academy of Sciences of the United States of America
Elkayam E, Faehnle CR, Morales M, et al. (2017) Multivalent Recruitment of Human Argonaute by GW182. Molecular Cell
Faehnle CR, Walleshauser J, Joshua-Tor L. (2017) Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nature Structural & Molecular Biology
Tocilj A, On KF, Yuan Z, et al. (2017) Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife. 6
Elkayam E, Parmar R, Brown CR, et al. (2016) siRNA carrying an (E)-vinylphosphonate moiety at the 5' end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2. Nucleic Acids Research
Shen C, Ipsaro JJ, Shi J, et al. (2015) NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler. Molecular Cell
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