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Anthony A. Estrada, Ph.D.

Affiliations: 
2008 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Organic Chemistry
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K. C. Nicolaou grad student 2008 UCSD
 (I. Studies directed towards the total synthesis of nocathiacin III. II. The development of a new synthetic technology for the construction of N-hydroxyindoles and synthesis of nocathiacin model systems. III. The development of a mild and selective method)
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Publications

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Chen H, Volgraf M, Do S, et al. (2018) Discovery of a Potent (4R,5S)-4-Fluoro-5-Methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist and its Methylene Phosphate Prodrug Guided By Molecular Modeling. Journal of Medicinal Chemistry
Shore DGM, Wasik KA, Lyssikatos JP, et al. (2015) Minisci alkylations of electron-deficient pyrimidines with alkyl carboxylic acids Tetrahedron Letters. 56: 4063-4066
Estrada AA, Chan BK, Baker-Glenn C, et al. (2014) Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. Journal of Medicinal Chemistry. 57: 921-36
Chan BK, Estrada AA, Chen H, et al. (2013) Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor. Acs Medicinal Chemistry Letters. 4: 85-90
Estrada AA, Shore DG, Blackwood E, et al. (2013) Pyrimidoaminotropanes as potent, selective, and efficacious small molecule kinase inhibitors of the mammalian target of rapamycin (mTOR). Journal of Medicinal Chemistry. 56: 3090-101
Estrada AA, Liu X, Baker-Glenn C, et al. (2012) Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. Journal of Medicinal Chemistry. 55: 9416-33
Estrada AA, Lyssikatos JP, St-Jean F, et al. (2011) Access to saturated fused pyrimidine derivatives via a flexible N -vinyl tertiary enamide synthesis Synlett. 2387-2391
Hanan EJ, Chan BK, Estrada AA, et al. (2010) Mild and general one-pot reduction and cyclization of aromatic and heteroaromatic 2-nitroamines to bicyclic 2 H -imidazoles Synlett. 2759-2764
Nicolaou KC, Chen JS, Edmonds DJ, et al. (2009) Recent advances in the chemistry and biology of naturally occurring antibiotics. Angewandte Chemie (International Ed. in English). 48: 660-719
Nicolaou KC, Chen JS, Edmonds DJ, et al. (2009) Fortschritte in der Chemie und Biologie natürlicher Antibiotika Angewandte Chemie. 121: 670-732
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