Gavin Williams
Affiliations: | 2009- | Chemistry | North Carolina State University, Raleigh, NC |
Area:
Natural products, drug discovery, chemical biologyWebsite:
https://williamslab.wordpress.ncsu.edu/?page_id=13Google:
"Gavin Williams"Mean distance: (not calculated yet)
Parents
Sign in to add mentorAlan Berry | grad student | 2002 | University of Leeds | |
(Engineering the mechanisms of C-C bond forming enzymes.) | ||||
Jon S. Thorson | post-doc | 2005-2009 | NCSU |
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Publications
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Calzini MA, Malico AA, Mitchler MM, et al. (2021) Protein engineering for natural product biosynthesis and synthetic biology applications. Protein Engineering, Design & Selection : Peds. 34 |
Kalkreuter E, Bingham KS, Keeler AM, et al. (2021) Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase. Nature Communications. 12: 2193 |
Mitchler MM, Garcia JM, Montero NE, et al. (2021) Transcription factor-based biosensors: a molecular-guided approach for natural product engineering. Current Opinion in Biotechnology. 69: 172-181 |
Malico AA, Calzini MA, Gayen AK, et al. (2020) Synthetic biology, combinatorial biosynthesis, and chemo-enzymatic synthesis of isoprenoids. Journal of Industrial Microbiology & Biotechnology |
Zin PPK, Williams G, Fourches D. (2020) SIME: synthetic insight-based macrolide enumerator to generate the V1B library of 1 billion macrolides Journal of Cheminformatics. 12 |
Zin PPK, Williams G, Fourches D. (2018) Cheminformatics-based enumeration and analysis of large libraries of macrolide scaffolds. Journal of Cheminformatics. 10: 53 |
Kasey C, Zerrad M, Li Y, et al. (2017) Development of transcription factor-based designer macrolide biosensors for metabolic engineering and synthetic biology. Acs Synthetic Biology |
Koryakina I, Kasey C, McArthur JB, et al. (2017) Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. Acs Chemical Biology. 12: 114-123 |
Koryakina I, McArthur J, Randall S, et al. (2013) Poly specific trans-acyltransferase machinery revealed via engineered acyl-CoA synthetases. Acs Chemical Biology. 8: 200-8 |
Parajuli N, Williams GJ. (2011) A high-throughput screen for directed evolution of aminocoumarin amide synthetases. Analytical Biochemistry. 419: 61-6 |