Avinash Muppidi

2014-2016 California Institute for Biomedical Research 
"Avinash Muppidi"
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Qing Lin grad student 2009-2014 SUNY Buffalo
 (Development of enabling technologies for translating bioactive peptides into therapeutics.)
Weijun Shen post-doc 2014-2016 California Institute for Biomedical Research
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Muppidi A, Lee SJ, Hsu CH, et al. (2018) Design and Synthesis of Potent, Long-Acting Lipidated Relaxin-2 Analogs. Bioconjugate Chemistry
Yang P, Zou H, Lee C, et al. (2018) A Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate-Induced Mouse Colitis Models. Journal of Medicinal Chemistry
Muppidi A, Zou H, Yang PY, et al. (2016) Design of Potent and Proteolytically Stable Oxyntomodulin Analogs. Acs Chemical Biology. 11: 324-8
Muppidi A, Doi K, Ramil CP, et al. (2014) Synthesis of cell-permeable stapled BH3 peptide-based Mcl-1 inhibitors containing simple aryl and vinylaryl cross-linkers. Tetrahedron. 70: 7740-7745
Muppidi A, Zhang H, Curreli F, et al. (2014) Design of antiviral stapled peptides containing a biphenyl cross-linker. Bioorganic & Medicinal Chemistry Letters. 24: 1748-51
Muppidi A, Doi K, Edwardraja S, et al. (2014) Targeted delivery of ubiquitin-conjugated BH3 peptide-based Mcl-1 inhibitors into cancer cells. Bioconjugate Chemistry. 25: 424-32
Muppidi A, Doi K, Edwardraja S, et al. (2012) Rational design of proteolytically stable, cell-permeable peptide-based selective Mcl-1 inhibitors. Journal of the American Chemical Society. 134: 14734-7
Muppidi A, Li X, Chen J, et al. (2011) Conjugation of spermine enhances cellular uptake of the stapled peptide-based inhibitors of p53-Mdm2 interaction. Bioorganic & Medicinal Chemistry Letters. 21: 7412-5
Muppidi A, Wang Z, Li X, et al. (2011) Achieving cell penetration with distance-matching cysteine cross-linkers: a facile route to cell-permeable peptide dual inhibitors of Mdm2/Mdmx. Chemical Communications (Cambridge, England). 47: 9396-8
Madden MM, Muppidi A, Li Z, et al. (2011) Synthesis of cell-permeable stapled peptide dual inhibitors of the p53-Mdm2/Mdmx interactions via photoinduced cycloaddition. Bioorganic & Medicinal Chemistry Letters. 21: 1472-5
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