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Brian K. Kobilka

Affiliations: 
Molecular & Cellular Physiology Stanford University, Palo Alto, CA 
Area:
Adrenergic receptors
Website:
http://med.stanford.edu/kobilkalab/index.html
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"Brian Kobilka"
Bio:

The Nobel Prize in Chemistry 2012 was awarded jointly to Robert J. Lefkowitz and Brian K. Kobilka "for studies of G-protein-coupled receptors"

Mean distance: 14.61 (cluster 11)
 
SNBCP
Cross-listing: Neurotree - Physiology Academic Tree

Parents

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Robert M. Carlson research assistant University of Minnesota Duluth
Conrad E. Firling research assistant University of Minnesota Duluth (Physiology Academic Tree)
 (A medium for the maintenance of Chironomus tentans salivary glands in vitro.)
Robert J. Lefkowitz post-doc 1984-1989 Duke

Children

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Andrew Kruse grad student Stanford
Aashish Manglik grad student Stanford
Yoon Seok Kim grad student 2015- Stanford (Neurotree)
Pejman Ghanouni grad student 2001 Stanford
Thomas P. Finsterbach grad student 2007 Stanford
Carl M. Hurt grad student 2007 Stanford
Juan J. Fung grad student 2009 Stanford
Daniel Hilger post-doc Stanford
Søren G.F. Rasmussen post-doc Stanford
Daniel M. Rosenbaum post-doc Stanford
Mark von Zastrow post-doc Stanford Medical School (Neurotree)
John Janetzko post-doc 2017- Stanford Medical School
Haoqing Wang post-doc 2019- Stanford
Uwe Klein post-doc 1995-1998 Stanford (Neurotree)
Peter Nollert post-doc 1999-2001 Stanford
Ka Young Chung post-doc 2008-2011 Stanford (Neurotree)
Hideaki E. Kato post-doc 2014-2019 Stanford School of Medicine

Collaborators

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Martin J. Lohse collaborator Stanford (Neurotree)
BETA: Related publications

Publications

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Heydenreich FM, Marti-Solano M, Sandhu M, et al. (2023) Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.). 382: eadh1859
Kumar KK, Wang H, Habrian C, et al. (2023) Step-wise activation of a Family C GPCR. Biorxiv : the Preprint Server For Biology
Toyoda Y, Zhu A, Kong F, et al. (2023) Structural basis of α-adrenergic receptor activation and recognition by an extracellular nanobody. Nature Communications. 14: 3655
Zhao J, Elgeti M, O'Brien ES, et al. (2023) Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. Biorxiv : the Preprint Server For Biology
Krishna Kumar K, Robertson MJ, Thadhani E, et al. (2023) Structural basis for activation of CB1 by an endocannabinoid analog. Nature Communications. 14: 2672
Xu X, Shonberg J, Kaindl J, et al. (2023) Constrained catecholamines gain βAR selectivity through allosteric effects on pocket dynamics. Nature Communications. 14: 2138
Heng J, Hu Y, Pérez-Hernández G, et al. (2023) Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor. Nature Communications. 14: 2005
Krishna Kumar K, O'Brien ES, Habrian CH, et al. (2023) Negative allosteric modulation of the glucagon receptor by RAMP2. Cell. 186: 1465-1477.e18
Papasergi-Scott MM, Pérez-Hernández G, Batebi H, et al. (2023) Time-resolved cryo-EM of G protein activation by a GPCR. Biorxiv : the Preprint Server For Biology
Xu J, Wang Q, Hübner H, et al. (2023) Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature Communications. 14: 376
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