Andrew McIver
Affiliations: | 2007-2012 | North Carolina State University, Raleigh, NC |
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Publications
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Rohde JM, Karavadhi S, Pragani R, et al. (2021) Discovery and Optimization of 2-1λ-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer. Journal of Medicinal Chemistry |
Urban DJ, Martinez NJ, Davis MI, et al. (2017) Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays. Scientific Reports. 7: 12758 |
McIver A, Zhang W, Liu Q, et al. (2016) Discovery of Macrocyclic Pyrimidines as MerTK-specific Inhibitors. Chemmedchem |
Buchanan MK, Needham CN, Neill NE, et al. (2016) Glycoconjugated Site-selective DNA-Methylating Agent Targeting Glucose Transporters on Glioma Cells. Biochemistry |
Zhang W, McIver AL, Stashko MA, et al. (2013) Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis. Journal of Medicinal Chemistry. 56: 9693-700 |
Govan JM, McIver AL, Riggsbee C, et al. (2012) Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives. Angewandte Chemie (International Ed. in English). 51: 9066-70 |
Govan JM, McIver AL, Deiters A. (2011) Stabilization and photochemical regulation of antisense agents through PEGylation. Bioconjugate Chemistry. 22: 2136-42 |
Dush MK, McIver AL, Parr MA, et al. (2011) Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chemistry & Biology. 18: 252-63 |
Georgianna WE, Lusic H, McIver AL, et al. (2010) Photocleavable polyethylene glycol for the light-regulation of protein function. Bioconjugate Chemistry. 21: 1404-7 |
McIver AL, Deiters A. (2010) Tricyclic alkaloid core structures assembled by a cyclotrimerization-coupled intramolecular nucleophilic substitution reaction. Organic Letters. 12: 1288-91 |