Luiz Augusto Basso
Affiliations: | Biochemistry | Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil |
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Sign in to add trainee| Luiz Pedro S. de Carvalho | grad student | 2000-2001 | Federal University of Rio Grande do Sul (UFRGS) |
| Rafael Guimaraes da Silva | grad student | 2005-2008 | Universidade Federal do Rio Grande do Sul (UFRGS) |
| Clarissa Melo Czekster | grad student | 2006-2008 | Federal University of Rio Grande do Sul |
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Publications
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| Joaquim AR, Lopes MS, Fortes IS, et al. (2024) Identification of antimycobacterial 8-hydroxyquinoline derivatives as in vitro enzymatic inhibitors of Mycobacterium tuberculosis enoyl-acyl carrier protein reductase. Bioorganic Chemistry. 151: 107705 |
| Borsoi AF, Silva Ramos A, Sperotto N, et al. (2024) Exploring Scaffold Hopping for Novel 2-(Quinolin-4-yloxy)acetamides with Enhanced Antimycobacterial Activity. Acs Medicinal Chemistry Letters. 15: 493-500 |
| Freitas de Freitas T, Roth CD, Abbadi BL, et al. (2022) Identification of potential inhibitors of Mycobacterium tuberculosis shikimate kinase: molecular docking, in silico toxicity and in vitro experiments. Journal of Computer-Aided Molecular Design. 1-12 |
| Paz JD, Denise de Moura Sperotto N, Ramos AS, et al. (2022) Novel 4-aminoquinolines: Synthesis, inhibition of the Mycobacterium tuberculosis enoyl-acyl carrier protein reductase, antitubercular activity, SAR, and preclinical evaluation. European Journal of Medicinal Chemistry. 245: 114908 |
| Galina L, Hopf FSM, Abbadi BL, et al. (2022) Evaluation of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase (DAHPS) as a Vulnerable Target in Mycobacterium tuberculosis. Microbiology Spectrum. e0072822 |
| Sidrônio MGS, Castelo Branco APOT, Abbadi BL, et al. (2021) Effects of tafenoquine against active, dormant and resistant Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 128: 102089 |
| Borsoi AF, Paz JD, Pissinate K, et al. (2021) Ultrasound-Assisted Synthesis of 4-Alkoxy-2-methylquinolines: An Efficient Method toward Antitubercular Drug Candidates. Molecules (Basel, Switzerland). 26 |
| Dalberto PF, de Souza EV, Abbadi BL, et al. (2020) Handling the Hurdles on the Way to Anti-tuberculosis Drug Development. Frontiers in Chemistry. 8: 586294 |
| Nunes JES, Duque MA, de Freitas TF, et al. (2020) Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs. Molecules (Basel, Switzerland). 25 |
| Borsoi AF, Paz JD, Abbadi BL, et al. (2020) Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents. European Journal of Medicinal Chemistry. 192: 112179 |