Rafael Guimaraes da Silva
Affiliations: | University of St Andrews, Saint Andrews, Scotland, United Kingdom | ||
| 2008-2012 | Biochemistry | Albert Einstein College of Medicine, New York, New York, United States |
Website:
https://www.st-andrews.ac.uk/biology/people/rgds/Google:
"Rafael Guimaraes da Silva"Bio:
https://scholar.google.com/citations?user=pQN1aFEAAAAJ&hl=en
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Parents
Sign in to add mentor| Luiz Augusto Basso | grad student | 2005-2008 | Universidade Federal do Rio Grande do Sul (UFRGS) |
| Vern L. Schramm | post-doc | 2008-2012 | Albert Einstein |
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Publications
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| Pečaver E, Zickuhr GM, Machado TFG, et al. (2025) Kinetic and Thermodynamic Characterization of Human 4-Oxo-l-proline Reductase Catalysis. Biochemistry |
| Read BJ, Mitchell JBO, da Silva RG. (2024) Allosteric activation unveils protein-mass modulation of ATP phosphoribosyltransferase product release. Communications Chemistry. 7: 77 |
| Tang P, Harding CJ, Dickson AL, et al. (2024) Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase. Acs Catalysis. 14: 3090-3102 |
| Carberry AE, Devi S, Harrison DJ, et al. (2024) Human 2'-Deoxynucleoside 5'-Phosphate N-Hydrolase 1: The Catalytic Roles of Tyr24 and Asp80. Chembiochem : a European Journal of Chemical Biology. e202400047 |
| Read BJ, Cadzow AF, Alphey MS, et al. (2023) Crystal Structure, Steady-State, and Pre-Steady-State Kinetics of ATP Phosphoribosyltransferase. Biochemistry |
| Devi S, Carberry AE, Zickuhr GM, et al. (2023) Human 2'-Deoxynucleoside 5'-Phosphate -Hydrolase 1: Mechanism of 2'-Deoxyuridine 5'-Monophosphate Hydrolysis. Biochemistry |
| Fisher G, Pečaver E, Read BJ, et al. (2023) Catalytic Cycle of the Bifunctional Enzyme Phosphoribosyl-ATP Pyrophosphohydrolase/Phosphoribosyl-AMP Cyclohydrolase. Acs Catalysis. 13: 7669-7679 |
| Machado TFG, da Silva RG. (2023) Employing deuterium kinetic isotope effects to uncover the mechanism of (R)-3-hydroxybutyrate dehydrogenase. Methods in Enzymology. 685: 225-240 |
| Fisher G, Corbella M, Alphey MS, et al. (2022) Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation. Nature Communications. 13: 7607 |
| Sweeney P, Galliford A, Kumar A, et al. (2022) Structure, dynamics, and molecular inhibition of the Staphylococcus aureus mA22-tRNA methyltransferase TrmK. The Journal of Biological Chemistry. 102040 |