Peter N. Lewis, Ph.D.
Affiliations: | University of Toronto, Toronto, ON, Canada |
Area:
Protein Structure, Epigenetics, neurodegeneration, drug discovery, artificial intelligenceWebsite:
http://biochemistry.utoronto.ca/person/peter-n-lewis/Google:
"peter n lewis"Bio:
Peter Noel Lewis (1946- )
B.Sc. (1968) Univ. of Calgary. Ph.D. (1972) Cornell.
Post doctoral fellow Portsmouth Polytechnic (1972-74).
Chair of Department (1991-96), (1997-01). Director
of the Program in Proteomics and Bioinformatics
(1998-2003). President of the Canadian Society of
Biochemistry, Molecular & Cellular Biology (1999-00).
Vice Dean, Research and International Relations, in
the Faculty of Medicine (2002- ). Among his graduate
students were Dae Chung, Guy Guillemette, Liliana
Attisano and Angus McQuibban.
Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Harold Abraham Scheraga | grad student | 1968-1973 | Cornell | |
| (PhD) | ||||
| E Morton Bradbury | research scientist | Portsmouth Polytechnic (Physics Tree) | ||
| (PDF supervisor) | ||||
Children
Sign in to add trainee| Dae Chung | grad student | 1980-1986 | University of Toronto |
| Neil Coombs | grad student | 1983-1986 | University of Toronto |
| Liliana Attisano | grad student | 1984-1990 | University of Toronto (Cell Biology Tree) |
| Gurbaksh Basi | grad student | 1987-1990 | University of Toronto |
| Peter Pawelek | grad student | 1988-1992 | University of Toronto |
| Dean Rowe-Magnus | grad student | 1991-1994 | University of Toronto (Microtree) |
| J Guy Guillemette | grad student | 1992-1995 | University of Waterloo |
| George Angus McQuibban | grad student | 1992-1995 | University of Toronto |
| Ahlia Khan | grad student | 1999-2006 | University of Toronto |
Collaborators
Sign in to add collaborator| G Angus McQuibban | collaborator | 2013- | University of Toronto |
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Publications
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| Moskal N, Visanji NP, Gorbenko O, et al. (2023) An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets. Plos Biology. 21: e3001977 |
| Khan AN, Lewis PN. (2006) Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases Journal of Biological Chemistry. 281: 11702-11711 |
| Khan AN, Lewis PN. (2005) Unstructured conformations are a substrate requirement for the Sir2 family of NAD-dependent protein deacetylases Journal of Biological Chemistry. 280: 36073-36078 |
| Lewis PN, Balaram R, Commisso-Cappelli C, et al. (2000) Structure - Function Studies of the Yeast Histone Deacetylase Hos3p Biochemical Society Transactions. 28: A250-A250 |
| McQuibban GA, Commisso-Cappelli CN, Lewis PN. (1998) Assembly, remodeling, and histone binding capabilities of yeast nucleosome assembly protein 1 Journal of Biological Chemistry. 273: 6582-6590 |
| Kleine TJ, Lewis PN, Lewis SA. (1997) Histone-induced damage of a mammalian epithelium: the role of protein and membrane structure. American Journal of Physiology. Cell Physiology. 273: C1925-C1936 |
| Kleine TJ, Lewis PN, Lewis SA. (1997) Histone-induced damage of a mammalian epithelium: The role of protein and membrane structure American Journal of Physiology - Cell Physiology. 273: C1925-C1936 |
| Chan S, Attisano L, Lewis PN. (1988) Histone H3 thiol reactivity and acetyltransferases in chicken erythrocyte nuclei Journal of Biological Chemistry. 263: 15643-15651 |
| Lewis PN, Guillemette JG, Chan S. (1988) Histone accessibility determined by lysine-specific acetylation in chicken erythrocyte nuclei European Journal of Biochemistry. 172: 135-145 |
| Chung DG, Lewis PN. (1986) Intermolecular histone H4 interactions in core nucleosomes. Biochemistry. 25: 2048-54 |