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William S. Kelley

Affiliations: 
Biological Sciences Carnegie Mellon University, Pittsburgh, PA 
Area:
Molecular biology
Website:
http://fords.haverford.edu/get-involved/awards/index.aspx?wp1631114594-slide=6
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"William S. Kelley"
Bio:

William S. Kelley ’63
William is a retired molecular biologist who has been employed both in academia and in the biotechnology industry. After graduation from Haverford and subsequent graduate work in biochemistry and molecular biology at M.I.T. and Tufts, he spent two years as a postdoctoral fellow at the University of Edinburgh and another postdoctoral year at Brandeis. From 1971–1980 he was a faculty member at Carnegie Mellon University but left academic life in Pittsburgh in 1980 to join Biogen, one of the first biotechnology start-up companies that had been organized to implement DNA cloning technology. For the next thirty years he was active in a variety of managerial and consulting roles in early phase companies located in Cambridge, Massachusetts.
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Parents

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Moselio Schaechter grad student 1968
 (Studies on the Life Cycle of the Ribosomes of Bacillus Megaterium)

Children

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Nigel D. F. Grindley post-doc 1973-1975 Carnegie Mellon

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Publications

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Kelley WS, Joyce CM. (1983) Genetic characterization of early amber mutations in the Escherichia coli polA gene and purification of the amber peptides. Journal of Molecular Biology. 164: 529-60
Joyce CM, Kelley WS, Grindley ND. (1982) Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I. The Journal of Biological Chemistry. 257: 1958-64
Murray NE, Kelley WS. (1979) Characterization of lambdapolA transducing phages; effective expression of the E. coli polA gene. Molecular & General Genetics : Mgg. 175: 77-87
Kelley WS, Chalmers K, Murray NE. (1977) Isolation and characterization of a lambdapolA transducing phage. Proceedings of the National Academy of Sciences of the United States of America. 74: 5632-6
Kelley WS, Grindley ND. (1976) Mapping of the polA locus of Escherichia coli K12: orientation in the amino- and carboxy-termini of the cistron. Molecular & General Genetics : Mgg. 147: 307-14
Grindley ND, Kelley WS. (1976) Effects of different alleles of the E. coli K12 pol A gene on the replication of non-transferring plasmids. Molecular & General Genetics : Mgg. 143: 311-8
Kelley WS, Whitfield HJ. (1971) Purification of an altered DNA polymerase from an E. coli strain with a pol mutation. Nature. 230: 33-6
Kelley WS, Schaechter M. (1970) Kinetic studies of the in vivo exchange of ribosome subunits in Bacillus megaterium. Journal of Molecular Biology. 50: 171-81
Kelley WS, Schaechter M. (1969) Magnesium ion-dependent dissociation of polysomes and free 70 s ribosomes in Bacillus megaterium. Journal of Molecular Biology. 42: 599-602
Kelley WS, Schaechter M. (1968) The "Life Cycle" of Bacterial Ribosomes Advances in Microbial Physiology. 2: 89-142
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