Ernst ter Haar, Ph.D.

Vertex Pharmaceuticals, Boston, MA, United States 
"Ernst ter Haar"
Mean distance: 9.95
Cross-listing: Crystallography Tree

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Balachandran R, ter Haar E, Yalowich JC, et al. (1999) Induction of human breast cancer cell apoptosis from G2/M preceded by stimulation into the cell cycle by Z-1,1-dichloro-2,3-diphenylcyclopropane. Biochemical Pharmacology. 57: 97-110
Balachandran R, ter Haar E, Welsh MJ, et al. (1998) The potent microtubule-stabilizing agent (+)-discodermolide induces apoptosis in human breast carcinoma cells--preliminary comparisons to paclitaxel. Anti-Cancer Drugs. 9: 67-76
ter Haar E, Hamel E, Balachandran R, et al. (1997) Cellular targets of the anti-breast cancer agent Z-1,1-dichloro-2,3-diphenylcyclopropane: type II estrogen binding sites and tubulin. Anticancer Research. 17: 1861-9
Jonnalagadda SS, ter Haar E, Hamel E, et al. (1997) Synthesis and biological evaluation of 1,1-dichloro-2,3-diarylcyclopropanes as antitubulin and anti-breast cancer agents. Bioorganic & Medicinal Chemistry. 5: 715-22
ter Haar E, Rosenkranz HS, Hamel E, et al. (1996) Computational and molecular modeling evaluation of the structural basis for tubulin polymerization inhibition by colchicine site agents. Bioorganic & Medicinal Chemistry. 4: 1659-71
ter Haar E, Day BW. (1996) Cytostatic and cytotoxic action of Z-1, 1-dichloro-2,3-diphenylcyclopropane in three human breast cancer cell lines. Anticancer Research. 16: 1107-15
ter Haar E, Day BW, Rosenkranz HS. (1996) Direct tubulin polymerization perturbation contributes significantly to the induction of micronuclei in vivo. Mutation Research. 350: 331-7
ter Haar E, Kowalski RJ, Hamel E, et al. (1996) Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol. Biochemistry. 35: 243-50
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