Hao Wu

Biological Chemistry and Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
structural immunology
"Hao Wu"


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Du G, Healy LB, David L, et al. (2023) ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation. Biorxiv : the Preprint Server For Biology
Paidimuddala B, Cao J, Nash G, et al. (2023) Mechanism of NAIP-NLRC4 inflammasome activation revealed by cryo-EM structure of unliganded NAIP5. Nature Structural & Molecular Biology
Fu J, Wu H. (2022) Structural Mechanisms of NLRP3 Inflammasome Assembly and Activation. Annual Review of Immunology
Tang L, Dong S, Rasheed N, et al. (2022) Vibrio parahaemolyticus prey targeting requires autoproteolysis-triggered dimerization of the type VI secretion system effector RhsP. Cell Reports. 41: 111732
Xiao L, Magupalli VG, Wu H. (2022) Cryo-EM structures of the active NLRP3 inflammasome disk. Nature
Fontana P, Dong Y, Pi X, et al. (2022) Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold. Science (New York, N.Y.). 376: eabm9326
Zheng W, Shen C, Wang L, et al. (2022) pH regulates potassium conductance and drives a constitutive proton current in human TMEM175. Science Advances. 8: eabm1568
Xiong X, Tian S, Yang P, et al. (2022) Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors. Cell
Vora SM, Fontana P, Mao T, et al. (2022) Targeting stem-loop 1 of the SARS-CoV-2 5' UTR to suppress viral translation and Nsp1 evasion. Proceedings of the National Academy of Sciences of the United States of America. 119
Andreeva L, David L, Rawson S, et al. (2021) NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. Cell
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