Agnieszka Kowalczyk, Ph.D.

Affiliations: 
2000 Vanderbilt University, Nashville, TN 
Area:
Organic Chemistry
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Thomas M. Harris grad student 2000 Vanderbilt
 (Synthesis of site-specifically adducted DNA: Part I. beta-hydroxyalkyl adduct at the N1 position of inosine. Part II. Intrastrand crosslinks between guanine N(2) positions.)
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Publications

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Merritt WK, Kowalczyk A, Scholdberg TA, et al. (2005) Dual roles of glycosyl torsion angle conformation and stereochemical configuration in butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adducts: a structural perspective. Chemical Research in Toxicology. 18: 1098-107
Kowalczyk A, Carmical JR, Zou Y, et al. (2002) Intrastrand DNA cross-links as tools for studying DNA replication and repair: two-, three-, and four-carbon tethers between the N(2) positions of adjacent guanines. Biochemistry. 41: 3109-18
Rodriguez DA, Kowalczyk A, Ward JB, et al. (2001) Point mutations induced by 1,2-epoxy-3-butene N1 deoxyinosine adducts. Environmental and Molecular Mutagenesis. 38: 292-6
Kowalczyk A, Harris CM, Harris TM. (2001) Synthesis and characterization of oligodeoxynucleotides containing an N1 beta-hydroxyalkyl adduct of 2'-deoxyinosine. Chemical Research in Toxicology. 14: 746-53
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