Stephen E Halford

Affiliations: 
1968-1971 Biochemistry University of Bristol, Bristol, England, United Kingdom 
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"Stephen Halford"
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Smith RM, Pernstich C, Halford SE. (2014) TstI, a Type II restriction-modification protein with DNA recognition, cleavage and methylation functions in a single polypeptide. Nucleic Acids Research. 42: 5809-22
Smith RM, Marshall JJ, Jacklin AJ, et al. (2013) Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA. Nucleic Acids Research. 41: 391-404
Smith RM, Jacklin AJ, Marshall JJ, et al. (2013) Organization of the BcgI restriction-modification protein for the transfer of one methyl group to DNA. Nucleic Acids Research. 41: 405-17
Laurens N, Rusling DA, Pernstich C, et al. (2012) DNA looping by FokI: The impact of twisting and bending rigidity on protein-induced looping dynamics Nucleic Acids Research. 40: 4988-4997
Rusling DA, Laurens N, Pernstich C, et al. (2012) DNA looping by FokI: The impact of synapse geometry on loop topology at varied site orientations Nucleic Acids Research. 40: 4977-4987
Pernstich C, Halford SE. (2012) Illuminating the reaction pathway of the FokI restriction endonuclease by fluorescence resonance energy transfer Nucleic Acids Research. 40: 1203-1213
Marshall JJ, Smith RM, Ganguly S, et al. (2011) Concerted action at eight phosphodiester bonds by the BcgI restriction endonuclease. Nucleic Acids Research. 39: 7630-40
Halford SE, Catto LE, Pernstich C, et al. (2011) The reaction mechanism of FokI excludes the possibility of targeting zinc finger nucleases to unique DNA sites Biochemical Society Transactions. 39: 584-588
Grippon S, Zhao Q, Robinson T, et al. (2011) Differential modes of DNA binding by mismatch uracil DNA glycosylase from Escherichia coli: implications for abasic lesion processing and enzyme communication in the base excision repair pathway. Nucleic Acids Research. 39: 2593-603
Marshall JJ, Halford SE. (2010) The type IIB restriction endonucleases. Biochemical Society Transactions. 38: 410-6
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