| Year |
Citation |
Score |
| 2014 |
Smith RM, Pernstich C, Halford SE. TstI, a Type II restriction-modification protein with DNA recognition, cleavage and methylation functions in a single polypeptide. Nucleic Acids Research. 42: 5809-22. PMID 24634443 DOI: 10.1093/Nar/Gku187 |
0.592 |
|
| 2013 |
Smith RM, Marshall JJ, Jacklin AJ, Retter SE, Halford SE, Sobott F. Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA. Nucleic Acids Research. 41: 391-404. PMID 23147005 DOI: 10.1093/Nar/Gks1023 |
0.572 |
|
| 2013 |
Smith RM, Jacklin AJ, Marshall JJ, Sobott F, Halford SE. Organization of the BcgI restriction-modification protein for the transfer of one methyl group to DNA. Nucleic Acids Research. 41: 405-17. PMID 23147004 DOI: 10.1093/Nar/Gks1000 |
0.54 |
|
| 2012 |
Laurens N, Rusling DA, Pernstich C, Brouwer I, Halford SE, Wuite GJL. DNA looping by FokI: The impact of twisting and bending rigidity on protein-induced looping dynamics Nucleic Acids Research. 40: 4988-4997. PMID 22373924 DOI: 10.1093/Nar/Gks184 |
0.607 |
|
| 2012 |
Rusling DA, Laurens N, Pernstich C, Wuite GJL, Halford SE. DNA looping by FokI: The impact of synapse geometry on loop topology at varied site orientations Nucleic Acids Research. 40: 4977-4987. PMID 22362745 DOI: 10.1093/Nar/Gks183 |
0.595 |
|
| 2012 |
Pernstich C, Halford SE. Illuminating the reaction pathway of the FokI restriction endonuclease by fluorescence resonance energy transfer Nucleic Acids Research. 40: 1203-1213. PMID 21993298 DOI: 10.1093/Nar/Gkr809 |
0.539 |
|
| 2011 |
Marshall JJ, Smith RM, Ganguly S, Halford SE. Concerted action at eight phosphodiester bonds by the BcgI restriction endonuclease. Nucleic Acids Research. 39: 7630-40. PMID 21653548 DOI: 10.1093/Nar/Gkr453 |
0.674 |
|
| 2011 |
Halford SE, Catto LE, Pernstich C, Rusling DA, Sanders KL. The reaction mechanism of FokI excludes the possibility of targeting zinc finger nucleases to unique DNA sites Biochemical Society Transactions. 39: 584-588. PMID 21428944 DOI: 10.1042/Bst0390584 |
0.616 |
|
| 2011 |
Grippon S, Zhao Q, Robinson T, Marshall JJ, O'Neill RJ, Manning H, Kennedy G, Dunsby C, Neil M, Halford SE, French PM, Baldwin GS. Differential modes of DNA binding by mismatch uracil DNA glycosylase from Escherichia coli: implications for abasic lesion processing and enzyme communication in the base excision repair pathway. Nucleic Acids Research. 39: 2593-603. PMID 21112870 DOI: 10.1093/Nar/Gkq913 |
0.578 |
|
| 2010 |
Marshall JJ, Halford SE. The type IIB restriction endonucleases. Biochemical Society Transactions. 38: 410-6. PMID 20298193 DOI: 10.1042/Bst0890410 |
0.512 |
|
| 2010 |
Sasnauskas G, Zakrys L, Zaremba M, Cosstick R, Gaynor JW, Halford SE, Siksnys V. A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3′-5′ and 5'-3' strands by rotating a single active site Nucleic Acids Research. 38: 2399-2410. PMID 20047964 DOI: 10.1093/Nar/Gkp1194 |
0.561 |
|
| 2010 |
Sobott F, Halford SE, Jacklin AJ, Marshall JJT, Smith RM. DNA Nanomachines Investigated By Non-Denaturing Mass Spectrometry Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.055 |
0.59 |
|
| 2009 |
Bellamy SRW, Kovacheva YS, Zulkipli IH, Halford SE. Differences between Ca2+ and Mg2+ in DNA binding and release by the SfiI restriction endonuclease: Implications for DNA looping Nucleic Acids Research. 37: 5443-5453. PMID 19596810 DOI: 10.1093/Nar/Gkp569 |
0.524 |
|
| 2009 |
Laurens N, Bellamy SRW, Harms AF, Kovacheva YS, Halford SE, Wuite GJL. Dissecting protein-induced DNA looping dynamics in real time Nucleic Acids Research. 37: 5454-5464. PMID 19586932 DOI: 10.1093/Nar/Gkp570 |
0.567 |
|
| 2009 |
Halford SE. An end to 40 years of mistakes in DNA-protein association kinetics? Biochemical Society Transactions. 37: 343-348. PMID 19290859 DOI: 10.1042/Bst0370343 |
0.564 |
|
| 2009 |
Sanders KL, Catto LE, Bellamy SRW, Halford SE. Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands Nucleic Acids Research. 37: 2105-2115. PMID 19223323 DOI: 10.1093/Nar/Gkp046 |
0.627 |
|
| 2009 |
Laurens N, Pernstich C, Catto LE, Harms AF, Kovacheva YS, Bellamy SRW, Halford SE, Wuite GJL. The Impact of Bending and Twisting Rigidity of DNA on Protein Induced Looping Dynamics Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1971 |
0.603 |
|
| 2008 |
Bellamy SRW, Mina P, Retter SE, Halford SE. Fidelity of DNA Sequence Recognition by the SfiI Restriction Endonuclease Is Determined by Communications between Its Two DNA-Binding Sites Journal of Molecular Biology. 384: 557-563. PMID 18848951 DOI: 10.1016/J.Jmb.2008.09.057 |
0.641 |
|
| 2008 |
Sasnauskas G, Connolly BA, Halford SE, Siksnys V. Template-directed addition of nucleosides to DNA by the BfiI restriction enzyme Nucleic Acids Research. 36: 3969-3977. PMID 18515343 DOI: 10.1093/nar/gkn343 |
0.549 |
|
| 2008 |
Catto LE, Bellamy SRW, Retter SE, Halford SE. Dynamics and consequences of DNA looping by the FokI restriction endonuclease Nucleic Acids Research. 36: 2073-2081. PMID 18276642 DOI: 10.1093/Nar/Gkn051 |
0.635 |
|
| 2007 |
Bellamy SR, Milsom SE, Kovacheva YS, Sessions RB, Halford SE. A switch in the mechanism of communication between the two DNA-binding sites in the SfiI restriction endonuclease. Journal of Molecular Biology. 373: 1169-83. PMID 17870087 DOI: 10.1016/J.Jmb.2007.08.030 |
0.619 |
|
| 2007 |
Sasnauskas G, Connolly BA, Halford SE, Siksnys V. Site-specific DNA transesterification catalyzed by a restriction enzyme Proceedings of the National Academy of Sciences of the United States of America. 104: 2115-2120. PMID 17267608 DOI: 10.1073/Pnas.0608689104 |
0.613 |
|
| 2007 |
Marshall JJ, Gowers DM, Halford SE. Restriction endonucleases that bridge and excise two recognition sites from DNA. Journal of Molecular Biology. 367: 419-31. PMID 17266985 DOI: 10.1016/J.Jmb.2006.12.070 |
0.642 |
|
| 2006 |
Catto LE, Ganguly S, Milsom SE, Welsh AJ, Halford SE. Protein assembly and DNA looping by the FokI restriction endonuclease Nucleic Acids Research. 34: 1711-1720. PMID 16556912 DOI: 10.1093/Nar/Gkl076 |
0.673 |
|
| 2006 |
Murphy TA, Catto LE, Halford SE, Hadfield AT, Minor W, Walsh TR, Spencer J. Crystal structure of Pseudomonas aeruginosa SPM-1 provides insights into variable zinc affinity of metallo-beta-lactamases. Journal of Molecular Biology. 357: 890-903. PMID 16460758 DOI: 10.1016/J.Jmb.2006.01.003 |
0.386 |
|
| 2005 |
Gowers DM, Wilson GG, Halford SE. Measurement of the contributions of 1D and 3D pathways to the translocation of a protein along DNA Proceedings of the National Academy of Sciences of the United States of America. 102: 15883-15888. PMID 16243975 DOI: 10.1073/Pnas.0505378102 |
0.611 |
|
| 2005 |
Wood KM, Daniels LE, Halford SE. Long-range communications between DNA sites by the dimeric restriction endonuclease SgrAI. Journal of Molecular Biology. 350: 240-53. PMID 15923010 DOI: 10.1016/J.Jmb.2005.04.053 |
0.647 |
|
| 2005 |
Bellamy SR, Milsom SE, Scott DJ, Daniels LE, Wilson GG, Halford SE. Cleavage of individual DNA strands by the different subunits of the heterodimeric restriction endonuclease BbvCI. Journal of Molecular Biology. 348: 641-53. PMID 15826661 DOI: 10.1016/J.Jmb.2005.02.035 |
0.396 |
|
| 2004 |
Gowers DM, Bellamy SRW, Halford SE. One recognition sequence, seven restriction enzymes, five reaction mechanisms Nucleic Acids Research. 32: 3469-3479. PMID 15226412 DOI: 10.1093/Nar/Gkh685 |
0.604 |
|
| 2004 |
Halford SE, Marko JF. How do site-specific DNA-binding proteins find their targets? Nucleic Acids Research. 32: 3040-52. PMID 15178741 DOI: 10.1093/Nar/Gkh624 |
0.576 |
|
| 2004 |
Halford SE, Welsh AJ, Szczelkun MD. Enzyme-mediated DNA looping Annual Review of Biophysics and Biomolecular Structure. 33: 1-24. PMID 15139802 DOI: 10.1146/Annurev.Biophys.33.110502.132711 |
0.685 |
|
| 2004 |
Embleton ML, Vologodskii AV, Halford SE. Dynamics of DNA loop capture by the SfiI restriction endonuclease on supercoiled and relaxed DNA. Journal of Molecular Biology. 339: 53-66. PMID 15123420 DOI: 10.1016/J.Jmb.2004.03.046 |
0.611 |
|
| 2004 |
Zaremba M, Urbanke C, Halford SE, Siksnys V. Generation of the BfiI Restriction Endonuclease from the Fusion of a DNA Recognition Domain to a Non-specific Nuclease from the Phospholipase D Superfamily Journal of Molecular Biology. 336: 81-92. PMID 14741205 DOI: 10.1016/J.Jmb.2003.12.012 |
0.477 |
|
| 2003 |
Kingston IJ, Gormley NA, Halford SE. DNA supercoiling enables the Type IIS restriction enzyme BspMI to recognise the relative orientation of two DNA sequences Nucleic Acids Research. 31: 5221-5228. PMID 12954757 DOI: 10.1093/Nar/Gkg743 |
0.648 |
|
| 2003 |
Sasnauskas G, Halford SE, Siksnys V. How the BfiI restriction enzyme uses one active site to cut two DNA strands Proceedings of the National Academy of Sciences of the United States of America. 100: 6410-6415. PMID 12750473 DOI: 10.1073/Pnas.1131003100 |
0.65 |
|
| 2003 |
Roberts RJ, Belfort M, Bestor T, Bhagwat AS, Bickle TA, Bitinaite J, Blumenthal RM, Degtyarev SKh, Dryden DT, Dybvig K, Firman K, Gromova ES, Gumport RI, Halford SE, Hattman S, et al. A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic Acids Research. 31: 1805-12. PMID 12654995 DOI: 10.1093/Nar/Gkg274 |
0.453 |
|
| 2003 |
Daniels LE, Wood KM, Scott DJ, Halford SE. Subunit assembly for DNA cleavage by restriction endonuclease SgrAI. Journal of Molecular Biology. 327: 579-91. PMID 12634054 DOI: 10.1016/S0022-2836(03)00143-8 |
0.668 |
|
| 2003 |
Gowers DM, Halford SE. Protein motion from non-specific to specific DNA by three-dimensional routes aided by supercoiling Embo Journal. 22: 1410-1418. PMID 12628933 DOI: 10.1093/Emboj/Cdg125 |
0.58 |
|
| 2003 |
Lagunavicius A, Sasnauskas G, Halford SE, Siksnys V. The metal-independent type IIs restriction enzyme BfiI is a dimer that binds two DNA sites but has only one catalytic centre Journal of Molecular Biology. 326: 1051-1064. PMID 12589753 DOI: 10.1016/S0022-2836(03)00020-2 |
0.631 |
|
| 2002 |
Halford SE, Szczelkun MD. How to get from A to B: Strategies for analysing protein motion on DNA European Biophysics Journal. 31: 257-267. PMID 12122472 DOI: 10.1007/S00249-002-0224-4 |
0.603 |
|
| 2002 |
Williams SA, Halford SE. Communications between catalytic sites in the protein-DNA synapse by the SfiI endonuclease Journal of Molecular Biology. 318: 387-394. PMID 12051845 DOI: 10.1016/S0022-2836(02)00019-0 |
0.608 |
|
| 2002 |
Gormley NA, Hillberg AL, Halford SE. The type IIs restriction endonuclease BspMI is a tetramer that acts concertedly at two copies of an asymmetric DNA sequence Journal of Biological Chemistry. 277: 4034-4041. PMID 11729188 DOI: 10.1074/Jbc.M108442200 |
0.661 |
|
| 2002 |
Bath AJ, Milsom SE, Gormley NA, Halford SE. Many type IIs restriction endonucleases interact with two recognition sites before cleaving DNA Journal of Biological Chemistry. 277: 4024-4033. PMID 11729187 DOI: 10.1074/Jbc.M108441200 |
0.653 |
|
| 2001 |
Halford SE. Hopping, jumping and looping by restriction enzymes Biochemical Society Transactions. 29: 363-373. PMID 11497991 DOI: 10.1042/Bst0290363 |
0.687 |
|
| 2001 |
Milsom SE, Halford SE, Embleton ML, Szczelkun MD. Analysis of DNA looping interactions by type II restriction enzymes that require two copies of their recognition sites Journal of Molecular Biology. 311: 515-527. PMID 11493005 DOI: 10.1006/Jmbi.2001.4893 |
0.658 |
|
| 2001 |
Embleton ML, Siksnys V, Halford SE. DNA cleavage reactions by type II restriction enzymes that require two copies of their recognition sites Journal of Molecular Biology. 311: 503-514. PMID 11493004 DOI: 10.1006/Jmbi.2001.4892 |
0.62 |
|
| 2001 |
Williams SA, Halford SE. Sfil endonuclease activity is strongly influenced by the non-specific sequence in the middle of its recognition site Nucleic Acids Research. 29: 1476-1483. PMID 11266549 DOI: 10.1093/Nar/29.7.1476 |
0.592 |
|
| 2000 |
Stanford NP, Szczelkun MD, Marko JF, Halford SE. One- and three-dimensional pathways for proteins to reach specific DNA sites Embo Journal. 19: 6546-6557. PMID 11101527 DOI: 10.1093/Emboj/19.23.6546 |
0.607 |
|
| 2000 |
Halford SE, Gowers DM, Sessions RB. Two are better than one. Nature Structural Biology. 7: 705-7. PMID 10966631 DOI: 10.1038/78911 |
0.57 |
|
| 2000 |
Watson MA, Gowers DM, Halford SE. Alternative geometries of DNA looping: An analysis using the SfiI endonuclease Journal of Molecular Biology. 298: 461-475. PMID 10772863 DOI: 10.1006/Jmbi.2000.3676 |
0.616 |
|
| 2000 |
Gormley NA, Bath AJ, Halford SE. Reactions of BglI and other type II restriction endonucleases with discontinuous recognition sites Journal of Biological Chemistry. 275: 6928-6936. PMID 10702254 DOI: 10.1074/Jbc.275.10.6928 |
0.659 |
|
| 1999 |
Halford SE, Bilcock DT, Stanford NP, Williams SA, Milsom SE, Gormley NA, Watson MA, Bath AJ, Embleton ML, Gowers DM, Daniels LE, Parry SH, Szczelkun MD. Restriction endonuclease reactions requiring two recognition sites Biochemical Society Transactions. 27: 696-699. PMID 10917669 DOI: 10.1042/Bst0270696 |
0.441 |
|
| 1999 |
Bilcock DT, Daniels LE, Bath AJ, Halford SE. Reactions of type II restriction endonucleases with 8-base pair recognition sites Journal of Biological Chemistry. 274: 36379-36386. PMID 10593932 DOI: 10.1074/Jbc.274.51.36379 |
0.631 |
|
| 1999 |
Thomas MP, Brady RL, Halford SE, Sessions RB, Baldwin GS. Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: A catalytic role for a main chain carbonyl group Nucleic Acids Research. 27: 3438-3445. PMID 10446231 DOI: 10.1093/Nar/27.17.3438 |
0.408 |
|
| 1999 |
Embleton ML, Williams SA, Watson MA, Halford SE. Specificity from the synapsis of DNA elements by the SfiI endonuclease Journal of Molecular Biology. 289: 785-797. PMID 10369761 DOI: 10.1006/Jmbi.1999.2822 |
0.602 |
|
| 1999 |
Stanford NP, Halford SE, Baldwin GS. DNA cleavage by the EcoRV restriction endonuclease: pH dependence and proton transfers in catalysis Journal of Molecular Biology. 288: 105-116. PMID 10329129 DOI: 10.1006/Jmbi.1999.2673 |
0.386 |
|
| 1999 |
Baldwin GS, Sessions RB, Erskine SG, Halford SE. DNA cleavage by the EcoRV restriction endonuclease: Roles of divalent metal ions in specificity and catalysis Journal of Molecular Biology. 288: 87-103. PMID 10329128 DOI: 10.1006/Jmbi.1999.2672 |
0.413 |
|
| 1999 |
Mizuuchi K, Nobbs TJ, Halford SE, Adzuma K, Qin J. A new method for determining the stereochemistry of DNA cleavage reactions: application to the SfiI and HpaII restriction endonucleases and to the MuA transposase. Biochemistry. 38: 4640-8. PMID 10194386 DOI: 10.1021/Bi990054P |
0.582 |
|
| 1999 |
Bilcock DT, Halford SE. DNA restriction dependent on two recognition sites: Activities of the SfiI restriction-modification system in Escherichia coli Molecular Microbiology. 31: 1243-1254. PMID 10096090 DOI: 10.1046/J.1365-2958.1999.01266.X |
0.655 |
|
| 1999 |
Halford SE. Restriction enzymes that act simultaneously at two DNA sites Biochemical Society Transactions. 27. DOI: 10.1042/Bst027A088 |
0.644 |
|
| 1998 |
Wentzell LM, Halford SE. DNA looping by the SfiI restriction endonuclease Journal of Molecular Biology. 281: 433-444. PMID 9698559 DOI: 10.1006/Jmbi.1998.1967 |
0.641 |
|
| 1998 |
Nobbs TJ, Szczelkun MD, Wentzell LM, Halford SE. DNA excision by the SfiI restriction endonuclease Journal of Molecular Biology. 281: 419-432. PMID 9698558 DOI: 10.1006/Jmbi.1998.1966 |
0.622 |
|
| 1998 |
Erskine SG, Halford SE. Reactions of the EcoRV restriction endonuclease with fluorescent oligodeoxynucleotides: identical equilibrium constants for binding to specific and non-specific DNA Journal of Molecular Biology. 275: 759-772. PMID 9480767 DOI: 10.1006/Jmbi.1997.1517 |
0.619 |
|
| 1997 |
Szczelkun MD, Janscak P, Firman K, Halford SE. Selection of non-specific DNA cleavage sites by the type IC restriction endonuclease EcoR124I Journal of Molecular Biology. 271: 112-123. PMID 9300058 DOI: 10.1006/Jmbi.1997.1172 |
0.667 |
|
| 1997 |
Sessions RB, Oram M, Szczelkun MD, Halford SE. Random walk models for DNA synapsis by resolvase. Journal of Molecular Biology. 270: 413-25. PMID 9237907 DOI: 10.1006/Jmbi.1997.1108 |
0.579 |
|
| 1997 |
Oram M, Marko JF, Halford SE. Communications between distant sites on supercoiled DNA from non-exponential kinetics for DNA synapsis by resolvase. Journal of Molecular Biology. 270: 396-412. PMID 9237906 DOI: 10.1006/Jmbi.1997.1109 |
0.647 |
|
| 1997 |
Erskine SG, Baldwin GS, Halford SE. Rapid-Reaction Analysis of Plasmid DNA Cleavage by the EcoRV Restriction Endonuclease† Biochemistry. 36: 7567-7576. PMID 9200708 DOI: 10.1021/Bi970155S |
0.631 |
|
| 1996 |
Vipond IB, Moon BJ, Halford SE. An isoleucine to leucine mutation that switches the cofactor requirement of the EcoRV restriction endonuclease from magnesium to manganese. Biochemistry. 35: 1712-21. PMID 8639650 DOI: 10.1021/Bi9523926 |
0.517 |
|
| 1996 |
Szczelkun MD, Dillingham MS, Janscak P, Firman K, Halford SE. Repercussions of DNA tracking by the type IC restriction endonuclease EcoR124I on linear, circular and catenated substrates The Embo Journal. 15: 6335-6347. DOI: 10.1002/J.1460-2075.1996.Tb01023.X |
0.666 |
|
| 1996 |
Szczelkun MD, Halford S. Recombination by resolvase to analyse DNA communications by the SfiI restriction endonuclease. The Embo Journal. 15: 1460-1469. DOI: 10.1002/J.1460-2075.1996.Tb00488.X |
0.662 |
|
| 1995 |
Vipond IB, Baldwin GS, Oram M, Erskine SG, Wentzell LM, Szczelkun MD, Nobbs TJ, Halford SE. A general assay for restriction endonucleases and other DNA-modifying enzymes with plasmid substrates. Molecular Biotechnology. 4: 259-68. PMID 8680932 DOI: 10.1007/Bf02779019 |
0.588 |
|
| 1995 |
Oram M, Szczelkun MD, Halford SE. Recombination. Pieces of the site-specific recombination puzzle. Current Biology : Cb. 5: 1106-9. PMID 8548278 DOI: 10.1016/S0960-9822(95)00222-3 |
0.621 |
|
| 1995 |
Soultanas P, Halford SE. Site-specific recombination at res sites containing DNA-binding sequences for both Tn21 resolvase and CAP. Journal of Molecular Biology. 245: 219-27. PMID 7844814 DOI: 10.1006/Jmbi.1994.0018 |
0.593 |
|
| 1995 |
Soultanas P, Oram M, Halford SE. Site-specific recombination at res sites containing DNA-binding sequences for both Tn21 and Tn3 resolvases. Journal of Molecular Biology. 245: 208-18. PMID 7844813 DOI: 10.1006/Jmbi.1994.0017 |
0.522 |
|
| 1995 |
Baldwin G, Vipond I, Halford S. Rapid reaction analysis of the catalytic cycle of the EcoRV restriction endonuclease. Biochemistry. 34: 705-714. PMID 7819266 DOI: 10.1021/Bi00002A038 |
0.491 |
|
| 1995 |
Vipond I, Baldwin G, Halford S. Divalent metal ions at the active sites of the EcoRV and EcoRI restriction endonucleases. Biochemistry. 34: 697-704. PMID 7819265 DOI: 10.1021/Bi00002A037 |
0.344 |
|
| 1995 |
Wentzell LM, Nobbs TJ, Halford SE. TheSfiI Restriction Endonuclease Makes a Four-strand DNA Break at Two Copies of its Recognition Sequence Journal of Molecular Biology. 248: 581-595. PMID 7752226 DOI: 10.1006/Jmbi.1995.0244 |
0.675 |
|
| 1995 |
Erskine SG, Halford SE. Interactions of the EcoRV restriction endonuclease with fluorescent oligodeoxynucleotides Gene. 157: 153-156. PMID 7607481 DOI: 10.1016/0378-1119(94)00616-Z |
0.437 |
|
| 1995 |
Nobbs TJ, Halford SE. Dna Cleavage At Two Recognition Sites By The Sfii Restriction Endonuclease: Salt Dependence Of Cis And Trans Interactions Between Distant Dna Sites Journal of Molecular Biology. 252: 399-411. PMID 7563060 DOI: 10.1006/Jmbi.1995.0506 |
0.669 |
|
| 1994 |
Stark WM, Parker CN, Halford SE, Boocock MR. Stereoselectivity of DNA catenane fusion by resolvase. Nature. 368: 76-8. PMID 8107889 DOI: 10.1038/368076A0 |
0.605 |
|
| 1994 |
Halford SE, Taylor JD, Vermote CLM, Vipond IB. Assays for restriction endonucleases using plasmid substrates. Methods of Molecular Biology. 30: 385-396. PMID 8004211 DOI: 10.1385/0-89603-256-6:385 |
0.413 |
|
| 1994 |
Taylor JD, Ackroyd AJ, Halford SE. The Gel Shift Assay for the Analysis of DNA-Protein Interactions Methods of Molecular Biology. 30: 263-279. PMID 8004201 DOI: 10.1385/0-89603-256-6:263 |
0.488 |
|
| 1994 |
Oram M, Shipstone E, Halford SE. Synapsis by Tn3 resolvase: speed and dependence on DNA supercoiling. Biochemical Society Transactions. 22: 303S. PMID 7821562 DOI: 10.1042/Bst022303S |
0.643 |
|
| 1994 |
Wentzell LM, Oram M, Halford SE. Purification and characterisation of the SfiI restriction endonuclease. Biochemical Society Transactions. 22: 302S. PMID 7821561 DOI: 10.1042/Bst022302S |
0.469 |
|
| 1994 |
Baldwin GS, Halford SE. Rapid reaction kinetics on the EcoRV restriction endonuclease. Biochemical Society Transactions. 22: 300-300. PMID 7821559 DOI: 10.1042/Bst022300S |
0.322 |
|
| 1993 |
Vipond I, Halford S. Structure–function correlation for the EcoRV restriction enzyme: from non‐specific binding to specific DNA cleavage Molecular Microbiology. 9: 225-231. PMID 8412677 DOI: 10.1111/J.1365-2958.1993.Tb01685.X |
0.638 |
|
| 1993 |
Hall SC, Halford SE. Specificity of DNA recognition in the nucleoprotein complex for site-specific recombination by Tn21 resolvase. Nucleic Acids Research. 21: 5712-5719. PMID 8284219 DOI: 10.1093/Nar/21.24.5712 |
0.56 |
|
| 1993 |
Roberts RJ, Halford SE. 2 Type II Restriction Endonucleases Cold Spring Harbor Monograph Archive. 25: 35-88. DOI: 10.1101/087969426.25.35 |
0.417 |
|
| 1992 |
Taylor JD, Halford SE. The activity of the EcoRV restriction endonuclease is influenced by flanking DNA sequences both inside and outside the DNA-protein complex Biochemistry. 31: 90-97. PMID 1731888 DOI: 10.1021/Bi00116A014 |
0.665 |
|
| 1992 |
Vermote CLM, Halford SE. EcoRV restriction endonuclease: communication between catalytic metal ions and DNA recognition. Biochemistry. 31: 6082-6089. PMID 1627551 DOI: 10.1021/Bi00141A018 |
0.63 |
|
| 1991 |
Parker CN, Halford SE. Dynamics of long-range interactions on DNA: The speed of synapsis during site-specific recombination by resolvase Cell. 66: 781-791. PMID 1652373 DOI: 10.1016/0092-8674(91)90121-E |
0.616 |
|
| 1990 |
Taylor JD, Goodall AJ, Vermote CL, Halford SE. Fidelity of DNA recognition by the EcoRV restriction/modification system in vivo. Biochemistry. 29: 10727-10733. PMID 2176880 DOI: 10.1021/Bi00500A003 |
0.659 |
|
| 1990 |
Avila P, Ackroyd AJ, Halford SE. DNA binding by mutants of Tn21 resolvase with DNA recognition functions from Tn3 resolvase. Journal of Molecular Biology. 216: 645-655. PMID 2175363 DOI: 10.1016/0022-2836(90)90389-4 |
0.649 |
|
| 1990 |
Ackroyd AJ, Avila P, Parker CN, Halford SE. Site-specific recombination by mutants of Tn21 resolvase with DNA recognition functions from Tn3 resolvase. Journal of Molecular Biology. 216: 633-643. PMID 2175362 DOI: 10.1016/0022-2836(90)90388-3 |
0.594 |
|
| 1989 |
Taylor JD, Halford SE. Discrimination between DNA sequences by the EcoRV restriction endonuclease Biochemistry. 28: 6198-6207. PMID 2675966 DOI: 10.1021/Bi00441A011 |
0.644 |
|
| 1989 |
Castell SE, Halford SE. DNA supercoiling determines the activation energy barrier for site specific recombination by Tn21 resolvase. Nucleic Acids Research. 17: 7045-7058. PMID 2550904 DOI: 10.1093/Nar/17.17.7045 |
0.607 |
|
| 1988 |
Nwosu VU, Connolly BA, Halford SE, Garnett J. The cloning, purification and characterization of the Eco RV modification methylase. Nucleic Acids Research. 16: 3705-20. PMID 2836798 DOI: 10.1093/Nar/16.9.3705 |
0.362 |
|
| 1988 |
Halford SE, Goodall AJ. Modes of DNA cleavage by the EcoRV restriction endonuclease. Biochemistry. 27: 1771-1777. PMID 2835097 DOI: 10.1021/Bi00405A058 |
0.604 |
|
| 1988 |
Castell SE, Halford SE. The role of DNA supercoiling in site-specific recombination by Tn21 resolvase Biochemical Society Transactions. 16: 760-761. DOI: 10.1042/Bst0160760 |
0.629 |
|
| 1988 |
Parker CN, Halford SE. How does resolvase sense the orientation of res sites that are distantly spaced Biochemical Society Transactions. 16: 754-755. DOI: 10.1042/Bst0160754 |
0.336 |
|
| 1986 |
Castell SE, Jordan SL, Halford SE. Site-specific recombination and topoisomerization by Tn21 resolvase: Role of metal ions Nucleic Acids Research. 14: 7213-7226. PMID 3020509 DOI: 10.1093/Nar/14.18.7213 |
0.539 |
|
| 1986 |
Halford SE, Lovelady BM, McCallum SA. Relaxed specificity of the EcoRV restriction endonuclease Gene. 41: 173-181. PMID 3011595 DOI: 10.1016/0378-1119(86)90096-X |
0.641 |
|
| 1986 |
Halford SE. DNA sequence specificity of Tn21 resolvase. Biochemical Society Transactions. 14: 216-217. PMID 3011546 DOI: 10.1042/Bst0140216 |
0.546 |
|
| 1986 |
Halford SE, Lovelady BM, McCALLUM S. Altered specificity of the EcoRV restriction endonuclease Biochemical Society Transactions. 14: 260-261. DOI: 10.1042/Bst0140260 |
0.4 |
|
| 1986 |
Bennett SP, Halford SE. Cytosine: cytosine formed in duplex DNA by the ligation of NciI- or CauII-cleaved DNA Biochemical Society Transactions. 14: 259-259. DOI: 10.1042/Bst0140259 |
0.568 |
|
| 1985 |
Halford SE, Jordan SL, Kirkbride EA. The resolvase protein from the transposon Tn 21 Mgg Molecular & General Genetics. 200: 169-175. PMID 2993810 DOI: 10.1007/Bf00383331 |
0.476 |
|
| 1983 |
Halford SE. How does EcoRI cleave its recognition site on DNA Trends in Biochemical Sciences. 8: 455-460. DOI: 10.1016/0968-0004(83)90035-X |
0.651 |
|
| 1982 |
Maxwell A, Halford SE. The SalGI restriction endonuclease. Enzyme specificity. Biochemical Journal. 203: 93-98. PMID 6285900 DOI: 10.1042/Bj2030093 |
0.745 |
|
| 1982 |
Maxwell A, Halford SE. The SalGI restriction endonuclease. Mechanism of DNA cleavage Biochemical Journal. 203: 85-92. PMID 6285899 DOI: 10.1042/Bj2030085 |
0.737 |
|
| 1982 |
Maxwell A, Halford SE. The SalGI restriction endonuclease. Purification and properties Biochemical Journal. 203: 77-84. PMID 6285898 DOI: 10.1042/Bj2030077 |
0.581 |
|
| 1981 |
Maxwell A, Halford SE. The Mechanism Of Dna Cleavage By Restriction Endonuclease Salgi Biochemical Society Transactions. 9. DOI: 10.1042/Bst009227Pc |
0.69 |
|
| 1980 |
Halford SE. The specificity of the EcoRI restriction endonuclease Biochemical Society Transactions. 8: 399-400. PMID 6249682 DOI: 10.1042/Bst0080399 |
0.429 |
|
| 1976 |
Hull WE, Halford SE, Gutfreund H, Sykes BD. 31P nuclear magnetic resonance study of alkaline phosphatase: the role of inorganic phosphate in limiting the enzyme turnover rate at alkaline pH. Biochemistry. 15: 1547-61. PMID 4092 DOI: 10.1021/Bi00652A028 |
0.3 |
|
| 1975 |
Halford SE. Stopped-flow fluorescence studies on saccharide binding to lysozyme. Biochemical Journal. 149: 411-422. PMID 1180904 DOI: 10.1042/Bj1490411 |
0.358 |
|
| 1975 |
Baldo JH, Halford SE, Patt SL, Sykes BD. The stepwise binding of small molecules to proteins. Nuclear magnetic resonance and temperature jump studies of the binding of 4-(N-acetylaminoglucosyl)-N-acetylglucosamine to lysozyme. Biochemistry. 14: 1893-9. PMID 1168493 DOI: 10.1021/Bi00680A014 |
0.304 |
|
| 1974 |
Halford SE, Schlesinger MJ. Mutationally altered rate constants in the mechanism of alkaline phosphatase. The Biochemical Journal. 141: 845-52. PMID 4618778 DOI: 10.1042/Bj1410845 |
0.588 |
|
| 1973 |
Halford SE, Schlesinger MJ. Letter: Hybrid tetramers of alkaline phosphatase. Journal of Molecular Biology. 81: 261-6. PMID 4591186 DOI: 10.1016/0022-2836(73)90194-0 |
0.567 |
|
| 1972 |
Halford SE. Escherichia coli alkaline phosphatase. Relaxation spectra of ligand binding Biochemical Journal. 126: 727-738. PMID 4561620 DOI: 10.1042/Bj1260727 |
0.387 |
|
| 1971 |
Halford SE. Escherichia coli alkaline phosphatase. An analysis of transient kinetics Biochemical Journal. 125: 319-327. PMID 4945877 DOI: 10.1042/Bj1250319 |
0.437 |
|
| 1969 |
Halford SE, Bennett NG, Trentham DR, Gutfeund H. A substate-induced conformation change in the reaction of alkaline phosphatase from Escherichia coli Biochemical Journal. 114: 243-251. PMID 4897458 DOI: 10.1042/Bj1140243 |
0.406 |
|
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