Milan Mrázek Fowkes
Affiliations: | University of Oxford, Oxford, United Kingdom |
Area:
Peptide chemistry, molecular imaging, biochemistryWebsite:
https://www.cmd.ox.ac.uk/people/milan-fowkesGoogle:
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Parents
Sign in to add mentor| Paul E. Brennan | research assistant | 2015-2016 | Oxford | |
| (Development of radiopaque peptides for cartilage imaging by CT) | ||||
| Leonard G Luyt | grad student | 2012-2014 | University of Western Ontario, Canada | |
| (MSc student; Development of peptidomimetic PET probes for imaging prostate cancer) | ||||
| Morten P. Meldal | grad student | 2018-2019 | Copenhagen University | |
| (Visiting DPhil student; combinatorial peptide library synthesis and proteinase screening) | ||||
| Paul E. Brennan | grad student | 2018-2021 | Oxford | |
| (DPhil student; Screening for selective ADAMTS-5 substrates to monitor proteinase activity) | ||||
| Jonathan M. Elkins | post-doc | 2021-2025 | Oxford | |
| (Fragment screening, protein synthesis and biophysical assays) | ||||
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Publications
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| Münzker L, Kimani SW, Fowkes MM, et al. (2024) A ligand discovery toolbox for the WWE domain family of human E3 ligases. Communications Biology. 7: 901 |
| Fowkes MM, Troeberg L, Brennan PE, et al. (2023) Development of Selective ADAMTS-5 Peptide Substrates to Monitor Proteinase Activity. Journal of Medicinal Chemistry. 66: 3522-3539 |
| Fowkes MM, Das Neves Borges P, Cacho-Nerin F, et al. (2022) Imaging articular cartilage in osteoarthritis using targeted peptide radiocontrast agents. Plos One. 17: e0268223 |
| Fowkes MM, Lim NH. (2020) Purification and Activity Determination of ADAMTS-4 and ADAMTS-5 and Their Domain Deleted Mutants. Methods in Molecular Biology (Clifton, N.J.). 2043: 75-91 |
| Lalonde T, Fowkes MM, Hou J, et al. (2019) Front Cover: Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a (ChemMedChem 20/2019) Chemmedchem. 14: 1743-1743 |
| Fowkes MM, Lalonde T, Yu L, et al. (2018) Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor. European Journal of Medicinal Chemistry. 157: 1500-1511 |
| Fowkes MM, Meldal MP, Vincent TL, et al. (2018) Screening for selective aggrecanase substrates to detect early proteolytic events in cartilage degradation Osteoarthritis and Cartilage. 26 |
| Hou J, Charron CL, Fowkes MM, et al. (2016) Bridging computational modeling with amino acid replacements to investigate GHS-R1a-peptidomimetic recognition. European Journal of Medicinal Chemistry. 123: 822-833 |