Joshua S. Chappie, PhD
Affiliations: | 2013- | Cornell University, Ithaca, NY, United States |
Area:
X-ray crystallography, cryo-EM, GTPases, ATPases, nucleases, anti-phage defense systems, host-pathogen interactions, plant virusesWebsite:
https://www.vet.cornell.edu/research-departments/faculty/joshua-chappie-phdGoogle:
"Joshua Chappie"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Christopher Miller | research assistant | 2001-2003 | Brandeis | |
| (Undergraduate research) | ||||
| Ronald Milligan | grad student | 2003-2009 | The Scripps Research Institute, La Jolla, CA | |
| Sandra Schmid | grad student | 2003-2009 | The Scripps Research Institute, La Jolla, CA (Cell Biology Tree) | |
| Frederick Dyda | post-doc | 2009-2013 | National Institute of Diabetes and Digestive and Kidney Diseases (Microtree) | |
Children
Sign in to add trainee| Anthony Bui | grad student | 2018- | Cornell |
| Christopher Hosford | grad student | 2013-2019 | Cornell |
| Carl Schiltz | grad student | 2014-2019 | Cornell |
| Myfanwy Adams | grad student | 2017-2023 | Cornell |
Collaborators
Sign in to add collaborator| Donald L. Court | collaborator | 2015- | National Cancer Institute - Frederick | |
| (Structural, functional, and genetic characterization of the lambda RexA and RexB) | ||||
| Lynn C Thomason | collaborator | 2015- | (Microtree) | |
| (Structural, functional, and genetic characterization of the lambda RexA and RexB) | ||||
| Craig Altier | collaborator | 2017- | Cornell | |
| (Characterization and modulation of AraC-type activators involved in Salmonella pathogenesis) | ||||
| Michelle L. Heck | collaborator | 2017- | USDA - ARS | |
| (Molecular mechanisms and inhibition of aphid-transmissible plant viruses) | ||||
| Thomas (Tom) Walz | collaborator | 2018- | Rockefeller | |
| (Structural characterization of McrBC restriction complexes) | ||||
| Marijn Ford | collaborator | 2016-2022 | University of Pittsburgh | |
BETA: Related publications
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Publications
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| Adams MC, Schiltz CJ, Sun J, et al. (2024) The crystal structure of bacteriophage λ RexA provides novel insights into the DNA binding properties of Rex-like phage exclusion proteins. Nucleic Acids Research |
| Dot EW, Thomason LC, Chappie JS. (2023) Everything OLD is new again: How structural, functional, and bioinformatic advances have redefined a neglected nuclease family. Molecular Microbiology |
| Schiltz CJ, Wilson JR, Hosford CJ, et al. (2022) Polerovirus N-terminal readthrough domain structures reveal molecular strategies for mitigating virus transmission by aphids. Nature Communications. 13: 6368 |
| Adams MC, Schiltz CJ, Heck ML, et al. (2021) Crystal structure of the potato leafroll virus coat protein and implications for viral assembly. Journal of Structural Biology. 214: 107811 |
| Chowdhury R, Pavinski Bitar PD, Adams MC, et al. (2021) AraC-type regulators HilC and RtsA are directly controlled by an intestinal fatty acid to regulate Salmonella invasion Molecular Microbiology |
| Thomason LC, Schiltz CJ, Court C, et al. (2021) Bacteriophage λ RexA and RexB Functions Assist the Transition from Lysogeny to Lytic Growth. Molecular Microbiology |
| Niu Y, Suzuki H, Hosford CJ, et al. (2020) Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes. Nature Communications. 11: 5907 |
| Bosire EM, Eade CR, Schiltz CJ, et al. (2020) Diffusible signal factors act through AraC-type transcriptional regulators as chemical cues to repress virulence of enteric pathogens Infection and Immunity |
| Hosford CJ, Adams MC, Niu Y, et al. (2020) The N-terminal domain of Staphylothermus marinus McrB shares structural homology with PUA-like RNA binding proteins Journal of Structural Biology |
| Gray S, Santiago ER, Chappie JS, et al. (2020) Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation With Cell-Cycle Progression in a Cyclin-Independent Manner Cell Reports. 32: 107858 |