Joshua S. Chappie, PhD - Publications

Affiliations: 
2013- Cornell University, Ithaca, NY, United States 
Area:
X-ray crystallography, cryo-EM, GTPases, ATPases, bacterial defense systems, host-pathogen interactions
Website:
https://www.vet.cornell.edu/research-departments/faculty/joshua-chappie-phd

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bosire EM, Eade CR, Schiltz CJ, Reid AJ, Troutman A, Chappie JS, Altier C. Diffusible signal factors act through AraC-type transcriptional regulators as chemical cues to repress virulence of enteric pathogens Infection and Immunity. PMID 32690633 DOI: 10.1128/IAI.00226-20  1
2020 Hosford CJ, Adams MC, Niu Y, Chappie JS. The N-terminal domain of Staphylothermus marinus McrB shares structural homology with PUA-like RNA binding proteins Journal of Structural Biology. PMID 32652237 DOI: 10.1016/j.jsb.2020.107572  1
2020 Gray S, Santiago ER, Chappie JS, Cohen, PE. Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation With Cell-Cycle Progression in a Cyclin-Independent Manner Cell Reports. 32: 107858. PMID 32640224 DOI: 10.1016/j.celrep.2020.107858  0.01
2020 Jaimes JA, André NM, Chappie JS, Millet JK, Whittaker GR. Phylogenetic Analysis and Structural Modeling of SARS-CoV-2 Spike Protein Reveals an Evolutionary Distinct and Proteolytically Sensitive Activation Loop Journal of Molecular Biology. pii: S0022-2836(20)3. PMID 32320687 DOI: doi: 10.1016/j.jmb.2020.04.009  0.01
2020 Schiltz CJ, Adams MC, Chappie JS. The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases. Nucleic Acids Research. 48: 2762-2776. PMID 32009148 DOI: 10.1093/nar/gkaa059  1
2020 Tornabene BA, Varlakhanova NV, Hosford CJ, Chappie JS, Ford MGJ. Structural and functional characterization of the dominant negative P-loop lysine mutation in the dynamin superfamily protein Vps1. Protein Science. 29: 1416-1428. PMID 31981262 DOI: doi: 10.1002/pro.3830  1
2020 Hosford CJ, Bui AQ, Chappie JS. The structure of the Thermococcus gammatolerans McrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs. Journal of Biological Chemistry. 295: 743-756. PMID 31822563 DOI: 10.1074/jbc.RA119.010188  1
2019 Partlow EA, Baker RW, Beacham GM, Chappie JS, Leschziner AE, Hollopeter G. A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife. PMID 31464684 DOI: 10.7554/eLife.50003  1
2019 Schiltz CJ, Lee A, Partlow EA, Hosford CJ, Chappie JS. Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage. Nucleic Acids Research. 47: 9448-9463. PMID 31400118 DOI: 10.1093/nar/gkz703  1
2019 Ford MGJ, Chappie JS. The structural biology of the dynamin-related proteins: New insights into a diverse, multitalented family. Traffic. 20: 717-740. PMID 31298797 DOI: 10.1111/tra.12676  1
2019 Murphy SG, Alvarez L, Adams MC, Liu S, Chappie JS, Cava F, Dörr T. Endopeptidase Regulation as a Novel Function of the Zur-Dependent Zinc Starvation Response. Mbio. 10. PMID 30782657 DOI: 10.1128/mBio.02620-18  1
2018 Varlakhanova NV, Alvarez FJD, Brady TM, Tornabene BA, Hosford CJ, Chappie JS, Zhang P, Ford MGJ. Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture. The Journal of Cell Biology. PMID 30087125 DOI: 10.1083/jcb.201712021  1
2018 Hosford CJ, Chappie JS. The crystal structure of the LlaJI.R1 N-terminal domain provides a model for site-specific DNA binding. The Journal of Biological Chemistry. 293: 11758-11771. PMID 29895618 DOI: 10.1074/jbc.RA118.001888  1
2014 Sundborger AC, Fang S, Heymann JA, Ray P, Chappie JS, Hinshaw JE. A dynamin mutant defines a superconstricted prefission state. Cell Reports. 8: 734-42. PMID 25088425 DOI: 10.1016/j.celrep.2014.06.054  1
2013 Chappie JS, Dyda F. Building a fission machine--structural insights into dynamin assembly and activation. Journal of Cell Science. 126: 2773-84. PMID 23781021 DOI: 10.1242/jcs.108845  1
2012 Maggin JE, James JA, Chappie JS, Dyda F, Hickman AB. The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization. Journal of Virology. 86: 3337-46. PMID 22205752 DOI: 10.1128/JVI.06775-11  1
2011 Chappie JS, Mears JA, Fang S, Leonard M, Schmid SL, Milligan RA, Hinshaw JE, Dyda F. A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke. Cell. 147: 209-22. PMID 21962517 DOI: 10.1016/j.cell.2011.09.003  1
2010 Wilson-Kubalek EM, Chappie JS, Arthur CP. Helical crystallization of soluble and membrane binding proteins. Methods in Enzymology. 481: 45-62. PMID 20887852 DOI: 10.1016/S0076-6879(10)81002-X  1
2010 Chappie JS, Acharya S, Leonard M, Schmid SL, Dyda F. G domain dimerization controls dynamin's assembly-stimulated GTPase activity. Nature. 465: 435-40. PMID 20428113 DOI: 10.1038/nature09032  1
2009 Chappie JS, Acharya S, Liu YW, Leonard M, Pucadyil TJ, Schmid SL. An intramolecular signaling element that modulates dynamin function in vitro and in vivo. Molecular Biology of the Cell. 20: 3561-71. PMID 19515832 DOI: 10.1091/mbc.E09-04-0318  1
2008 Littlefield KP, Ward AB, Chappie JS, Reedy MK, Bernstein SI, Milligan RA, Reedy MC. Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles. Journal of Molecular Biology. 381: 519-28. PMID 18588896 DOI: 10.1016/j.jmb.2008.06.029  1
2007 Ramachandran R, Surka M, Chappie JS, Fowler DM, Foss TR, Song BD, Schmid SL. The dynamin middle domain is critical for tetramerization and higher-order self-assembly. The Embo Journal. 26: 559-66. PMID 17170701 DOI: 10.1038/sj.emboj.7601491  1
2006 Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell. 127: 983-97. PMID 17129783 DOI: 10.1016/j.cell.2006.09.039  1
2005 Chappie JS, Cànaves JM, Han GW, Rife CL, Xu Q, Stevens RC. The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases. Structure (London, England : 1993). 13: 1385-96. PMID 16154095 DOI: 10.1016/j.str.2005.05.016  1
2003 Nimigean CM, Chappie JS, Miller C. Electrostatic tuning of ion conductance in potassium channels. Biochemistry. 42: 9263-8. PMID 12899612 DOI: 10.1021/bi0348720  1
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