Federico Bernal, Ph.D.

Laboratory of Protein Dynamics and Signaling National Cancer Institute, Rockville, MD, United States 
Cancer Chemical Biology
"Federico Bernal"
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K. C. Nicolaou grad student 1997-2002 Scripps Institute
 (Chemistry inspired by marine toxins: I. Synthesis and functionalization of the ABCD domain of azaspiracid. II. Ketene aminal phosphates: Dienes and organometallic couplings.)
Gregory L. Verdine post-doc 2002-2007 Harvard, CCB, BCMP
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Paquette AR, Payne SR, McKay GA, et al. (2022) RpoN-Based stapled peptides with improved DNA binding suppress virulence. Rsc Medicinal Chemistry. 13: 445-455
Payne SR, Pau DI, Whiting AL, et al. (2018) Inhibition of Bacterial Gene Transcription with an RpoN-Based Stapled Peptide. Cell Chemical Biology
Aguilar-Alonso F, Whiting AL, Kim YJ, et al. (2017) Biophysical and biological evaluation of optimized stapled peptide inhibitors of the linear ubiquitin chain assembly complex (LUBAC). Bioorganic & Medicinal Chemistry
Whiting AL, Aguilar-Alonso F, Mitala JJ, et al. (2017) Abstract 5235: Affecting activity of the linear ubiquitin chain assembly complex (LUBAC) with stapled alpha-helical peptides Cancer Research. 77: 5235-5235
Edwards AL, Meijer DH, Guerra RM, et al. (2016) Challenges in Targeting a Basic Helix-Loop-Helix Transcription Factor with Hydrocarbon-Stapled Peptides. Acs Chemical Biology
Bernal F, Katz SG. (2014) Synthesis of stabilized alpha-helical peptides. Methods in Molecular Biology (Clifton, N.J.). 1176: 107-14
Morrison BL, Whiting AL, Bernal F. (2014) Abstract 4071: SAH-p53-mediated inhibition of cell migration via alteration of actin dynamics Cancer Research. 74: 4071-4071
Whiting AL, Mitala JJ, Headley KM, et al. (2014) Abstract 3234: Covalent capture of protein binding partners using an azide-tagged, photo-reactive stapled alpha helical p53 peptide Cancer Research. 74: 3234-3234
Morrison BL, Russell E, Mitala J, et al. (2013) Abstract 839: An uncharacterized mechanism of cell death independent of p53 mutation status. Cancer Research. 73: 839-839
Felsenstein KM, Headley KM, Murray KA, et al. (2013) Abstract 2223: Identification of novel protein modulators of p53 family function using photochemical crosslinking of stapled peptides. Cancer Research. 73: 2223-2223
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