Emmett M. Leddin, Ph.D.
Affiliations: | 2017-2022 | Chemistry | University of North Texas, Denton, TX, United States |
Area:
Biochemistry, Physical Chemistry, Computational BiophysicsWebsite:
https://emleddin.github.io/Google:
"Emmett Leddin"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Bill Miller | research assistant | 2015-2017 | Truman State University |
| G. Andres Cisneros | grad student | 2017-2022 | University of North Texas |
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Publications
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| Maghsoud Y, Roy A, Leddin EM, et al. (2024) Effects of the Y432S Cancer-Associated Variant on the Reaction Mechanism of Human DNA Polymerase κ. Journal of Chemical Information and Modeling |
| Caputa DA, Blankenship QP, Smith ZD, et al. (2023) Computational drug discovery of an inhibitor of APOBEC3B as a treatment for epithelial cancers. Journal of Biomolecular Structure & Dynamics. 1-14 |
| Simonin-Wilmer I, Ossio R, Leddin EM, et al. (2022) Population-based analysis of variants in a cutaneous melanoma case-control cohort. Journal of Medical Genetics |
| Yeaton A, Cayanan G, Loghavi S, et al. (2022) The impact of inflammation-induced tumor plasticity during myeloid transformation. Cancer Discovery |
| Ravishankar K, Jiang X, Leddin EM, et al. (2022) Computational compensatory mutation discovery approach: Predicting a PARP1 variant rescue mutation. Biophysical Journal |
| Naseem-Khan S, Berger MB, Leddin EM, et al. (2022) Impact of Remdesivir Incorporation along the Primer Strand on SARS-CoV-2 RNA-Dependent RNA Polymerase. Journal of Chemical Information and Modeling |
| Hix MA, Leddin EM, Cisneros GA. (2021) Combining Evolutionary Conservation and Quantum Topological Analyses To Determine Quantum Mechanics Subsystems for Biomolecular Quantum Mechanics/Molecular Mechanics Simulations. Journal of Chemical Theory and Computation. 17: 4524-4537 |
| Leddin EM, Cisneros GA. (2019) Comparison of DNA and RNA substrate effects on TET2 structure. Advances in Protein Chemistry. 117: 91-112 |
| DeNizio JE, Liu MY, Leddin E, et al. (2018) Selectivity and Promiscuity in TET-mediated oxidation of 5-methylcytosine in DNA and RNA. Biochemistry |
| Antczak NM, Walker AR, Stern HR, et al. (2018) Characterization of nine cancer-associated variants in human DNA polymerase κ. Chemical Research in Toxicology |