Anthony Bruce Pinkerton - Publications

Affiliations: 
1996-2001 Chemistry Stanford University, Palo Alto, CA 

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Barak LS, Bai Y, Peterson S, Evron T, Urs N, Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Chung TD, Rodriguiz RM, Wetsel WC, Thomas JB, Hanson GR, Pinkerton AB, et al. ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse. Acs Chemical Biology. PMID 27119457 DOI: 10.1021/acschembio.6b00291  1
2015 Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, et al. SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. Cancer Research. PMID 26603897 DOI: 10.1158/0008-5472.CAN-15-0885  1
2015 Schreiber SL, Kotz JD, Li M, Aubé J, Austin CP, Reed JC, Rosen H, White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, de Souza A, Foley MA, ... ... Pinkerton AB, et al. Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes. Cell. 161: 1252-1265. PMID 26046436 DOI: 10.1016/j.cell.2015.05.023  1
2015 Peddibhotla S, Fontaine P, Leung CK, Maloney P, Hershberger PM, Wang Y, Bousquet MS, Luesch H, Mangravita-Novo A, Pinkerton AB, Smith LH, Malany S, Choe K. Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes. Acs Chemical Biology. 10: 1871-9. PMID 25946346 DOI: 10.1021/acschembio.5b00304  1
2015 von Roemeling CA, Marlow LA, Pinkerton AB, Crist A, Miller J, Tun HW, Smallridge RC, Copland JA. Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target. The Journal of Clinical Endocrinology and Metabolism. 100: E697-709. PMID 25675381 DOI: 10.1210/jc.2014-2764  1
2015 Zou H, Limpert AS, Zou J, Dembo A, Lee PS, Grant D, Ardecky R, Pinkerton AB, Magnuson GK, Goldman ME, Rong J, Teriete P, Sheffler DJ, Reed JC, Cosford ND. Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines. Acs Chemical Neuroscience. 6: 464-75. PMID 25544056 DOI: 10.1021/cn500297v  1
2015 Sheen CR, Kuss P, Narisawa S, Yadav MC, Nigro J, Wang W, Chhea TN, Sergienko EA, Kapoor K, Jackson MR, Hoylaerts MF, Pinkerton AB, O'Neill WC, Millán JL. Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 824-36. PMID 25428889 DOI: 10.1002/jbmr.2420  1
2014 Flaherty DP, Miller JR, Garshott DM, Hedrick M, Gosalia P, Li Y, Milewski M, Sugarman E, Vasile S, Salaniwal S, Su Y, Smith LH, Chung TD, Pinkerton AB, Aubé J, et al. Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response. Acs Medicinal Chemistry Letters. 5: 1278-1283. PMID 25530830 DOI: 10.1021/ml5003234  1
2014 Li S, Chang HH, Niewolik D, Hedrick MP, Pinkerton AB, Hassig CA, Schwarz K, Lieber MR. Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity. The Journal of Biological Chemistry. 289: 7825-34. PMID 24500713 DOI: 10.1074/jbc.M113.544874  1
2014 Ardecky RJ, Bobkova EV, Kiffer-Moreira T, Brown B, Ganji S, Zou J, Pass I, Narisawa S, Iano FG, Rosenstein C, Cheltsov A, Rascon J, Hedrick M, Gasior C, Forster A, ... ... Pinkerton AB, et al. Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes. Bioorganic & Medicinal Chemistry Letters. 24: 1000-4. PMID 24412070 DOI: 10.1016/j.bmcl.2013.12.043  1
2014 Hershberger PM, Hedrick MP, Peddibhotla S, Mangravita-Novo A, Gosalia P, Li Y, Gray W, Vicchiarelli M, Smith LH, Chung TD, Thomas JB, Caron MG, Pinkerton AB, Barak LS, Roth GP. Imidazole-derived agonists for the neurotensin 1 receptor. Bioorganic & Medicinal Chemistry Letters. 24: 262-7. PMID 24332089 DOI: 10.1016/j.bmcl.2013.11.026  1
2013 Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, ... ... Pinkerton AB, et al. Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor. Acs Medicinal Chemistry Letters. 4: 846-851. PMID 24611085 DOI: 10.1021/ml400176n  1
2013 Lee SH, Piran R, Keinan E, Pinkerton A, Levine F. Induction of β-cell replication by a synthetic HNF4α antagonist. Stem Cells (Dayton, Ohio). 31: 2396-407. PMID 23922283 DOI: 10.1002/stem.1496  1
2013 Teriete P, Pinkerton AB, Cosford ND. Inhibitors of tissue-nonspecific alkaline phosphatase (TNAP): from hits to leads. Methods in Molecular Biology (Clifton, N.J.). 1053: 85-101. PMID 23860648 DOI: 10.1007/978-1-62703-562-0_5  1
2013 Hershberger PM, Peddibhotla S, Sessions EH, Divlianska DB, Correa RG, Pinkerton AB, Reed JC, Roth GP. Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway. Beilstein Journal of Organic Chemistry. 9: 900-7. PMID 23766805 DOI: 10.3762/bjoc.9.103  1
2013 Feng Y, Lau E, Scortegagna M, Ruller C, De SK, Barile E, Krajewski S, Aza-Blanc P, Williams R, Pinkerton AB, Jackson M, Chin L, Pellecchia M, Bosenberg M, Ronai ZA. Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11. Pigment Cell & Melanoma Research. 26: 136-42. PMID 23035722 DOI: 10.1111/pcmr.12033  1
2013 Preuss J, Richardson AD, Pinkerton A, Hedrick M, Sergienko E, Rahlfs S, Becker K, Bode L. Identification and characterization of novel human glucose-6-phosphate dehydrogenase inhibitors. Journal of Biomolecular Screening. 18: 286-97. PMID 23023104 DOI: 10.1177/1087057112462131  1
2012 Maloney PR, Khan P, Hedrick M, Gosalia P, Milewski M, Li L, Roth GP, Sergienko E, Suyama E, Sugarman E, Nguyen K, Mehta A, Vasile S, Su Y, Stonich D, ... ... Pinkerton AB, et al. Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor. Bioorganic & Medicinal Chemistry Letters. 22: 6656-60. PMID 23010269 DOI: 10.1016/j.bmcl.2012.08.105  1
2012 Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, et al. HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chemistry & Biology. 19: 806-18. PMID 22840769 DOI: 10.1016/j.chembiol.2012.05.014  1
2012 Preuss J, Maloney P, Peddibhotla S, Hedrick MP, Hershberger P, Gosalia P, Milewski M, Li YL, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Mangravita-Novo A, ... ... Pinkerton AB, et al. Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro. Journal of Medicinal Chemistry. 55: 7262-72. PMID 22813531 DOI: 10.1021/jm300833h  1
2012 Preuss J, Hedrick M, Sergienko E, Pinkerton A, Mangravita-Novo A, Smith L, Marx C, Fischer E, Jortzik E, Rahlfs S, Becker K, Bode L. High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase. Journal of Biomolecular Screening. 17: 738-51. PMID 22496096 DOI: 10.1177/1087057112442382  1
2011 Sheffler DJ, Pinkerton AB, Dahl R, Markou A, Cosford ND. Recent progress in the synthesis and characterization of group II metabotropic glutamate receptor allosteric modulators. Acs Chemical Neuroscience. 2: 382-93. PMID 22860167 DOI: 10.1021/cn200008d  1
2011 Nagasawa JY, Song J, Chen H, Kim HW, Blazel J, Ouk S, Groschel B, Borges V, Ong V, Yeh LT, Girardet JL, Vernier JM, Raney AK, Pinkerton AB. 6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 760-3. PMID 21185178 DOI: 10.1016/j.bmcl.2010.11.108  1
2010 Herbert MR, Siegel DL, Staszewski L, Cayanan C, Banerjee U, Dhamija S, Anderson J, Fan A, Wang L, Rix P, Shiau AK, Rao TS, Noble SA, Heyman RA, Bischoff E, ... ... Pinkerton AB, et al. Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5. Bioorganic & Medicinal Chemistry Letters. 20: 5718-21. PMID 20801037 DOI: 10.1016/j.bmcl.2010.08.014  1
2007 Pinkerton AB, Lee TT, Hoffman TZ, Wang Y, Kahraman M, Cook TG, Severance D, Gahman TC, Noble SA, Shiau AK, Davis RL. Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 3562-9. PMID 17498954 DOI: 10.1016/j.bmcl.2007.04.076  1
2007 Pinkerton AB, Huang D, Cube RV, Hutchinson JH, Struthers M, Ayala JM, Vicario PP, Patel SR, Wisniewski T, DeMartino JA, Vernier JM. Diaryl substituted pyrazoles as potent CCR2 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 17: 807-13. PMID 17088058 DOI: 10.1016/j.bmcl.2006.10.060  1
2007 Pinkerton A. Imidazole based kinesin spindle protein inhibitors Expert Opinion On Therapeutic Patents. 17: 875-878. DOI: 10.1517/13543776.17.7.875  1
2005 Cube RV, Vernier JM, Hutchinson JH, Gardner MF, James JK, Rowe BA, Schaffhauser H, Daggett L, Pinkerton AB. 3-(2-Ethoxy-4-{4-[3-hydroxy-2-methyl-4-(3-methylbutanoyl)phenoxy]butoxy}phenyl)propanoic acid: a brain penetrant allosteric potentiator at the metabotropic glutamate receptor 2 (mGluR2). Bioorganic & Medicinal Chemistry Letters. 15: 2389-93. PMID 15837331 DOI: 10.1016/j.bmcl.2005.02.078  1
2005 Pinkerton AB, Cube RV, Hutchinson JH, James JK, Gardner MF, Rowe BA, Schaffhauser H, Rodriguez DE, Campbell UC, Daggett LP, Vernier JM. Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators. Bioorganic & Medicinal Chemistry Letters. 15: 1565-71. PMID 15745798 DOI: 10.1016/j.bmcl.2005.01.077  1
2004 Pinkerton AB, Cube RV, Hutchinson JH, James JK, Gardner MF, Schaffhauser H, Rowe BA, Daggett LP, Vernier JM. Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 2: 4-thiopyridyl acetophenones as non-tetrazole containing mGlu2 receptor potentiators. Bioorganic & Medicinal Chemistry Letters. 14: 5867-72. PMID 15501058 DOI: 10.1016/j.bmcl.2004.09.028  1
2004 Pinkerton AB, Cube RV, Hutchinson JH, Rowe BA, Schaffhauser H, Zhao X, Daggett LP, Vernier JM. Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones. Bioorganic & Medicinal Chemistry Letters. 14: 5329-32. PMID 15454221 DOI: 10.1016/j.bmcl.2004.08.020  1
2004 Hu E, Chua PC, Tehrani L, Nagasawa JY, Pinkerton AB, Rowe BA, Vernier JM, Hutchinson JH, Cosford ND. Pyrimidine methyl anilines: selective potentiators for the metabotropic glutamate 2 receptor. Bioorganic & Medicinal Chemistry Letters. 14: 5071-4. PMID 15380201 DOI: 10.1016/j.bmcl.2004.07.079  1
2004 Trost BM, Chung CK, Pinkerton AB. Stereocontrolled total synthesis of (+)-streptazolin by a palladium-catalyzed reductive diyne cyclization. Angewandte Chemie (International Ed. in English). 43: 4327-9. PMID 15368383 DOI: 10.1002/anie.200460058  1
2004 Pinkerton AB, Vernier JM, Schaffhauser H, Rowe BA, Campbell UC, Rodriguez DE, Lorrain DS, Baccei CS, Daggett LP, Bristow LJ. Phenyl-tetrazolyl acetophenones: discovery of positive allosteric potentiatiors for the metabotropic glutamate 2 receptor. Journal of Medicinal Chemistry. 47: 4595-9. PMID 15317469 DOI: 10.1021/jm040088h  1
2003 Schaffhauser H, Rowe BA, Morales S, Chavez-Noriega LE, Yin R, Jachec C, Rao SP, Bain G, Pinkerton AB, Vernier JM, Bristow LJ, Varney MA, Daggett LP. Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2. Molecular Pharmacology. 64: 798-810. PMID 14500736 DOI: 10.1124/mol.64.4.798  1
2003 Lorrain DS, Schaffhauser H, Campbell UC, Baccei CS, Correa LD, Rowe B, Rodriguez DE, Anderson JJ, Varney MA, Pinkerton AB, Vernier JM, Bristow LJ. Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1622-32. PMID 12825094 DOI: 10.1038/sj.npp.1300238  1
2002 Trost BM, Pinkerton AB. Formation of vinyl halides via a ruthenium-catalyzed three-component coupling. Journal of the American Chemical Society. 124: 7376-89. PMID 12071746 DOI: 10.1021/ja011426w  1
2002 Trost BM, Shen HC, Pinkerton AB. A synthesis of trisubstituted alkenes by a Ru-catalyzed addition. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 2341-9. PMID 12012418 DOI: 10.1002/1521-3765(20020517)8:10<2341::AID-CHEM2341>3.0.CO;2-A  1
2001 Trost BM, Pinkerton AB, Toste FD, Sperrle M. Synthesis of 1,1-disubstituted alkenes via a Ru-catalyzed addition. Journal of the American Chemical Society. 123: 12504-9. PMID 11741413 DOI: 10.1021/ja012009m  1
2001 Trost BM, Pinkerton AB, Seidel M. Ruthenium-catalyzed two-component addition to form 1,3-dienes: optimization, scope, applications, and mechanism. Journal of the American Chemical Society. 123: 12466-76. PMID 11741409 DOI: 10.1021/ja011428g  1
2001 Trost BM, Toste FD, Pinkerton AB. Non-metathesis ruthenium-catalyzed C-C bond formation. Chemical Reviews. 101: 2067-96. PMID 11710241 DOI: 10.1021/cr000666b  1
2001 Trost BM, Pinkerton AB. A three-component coupling approach to cyclopentanoids. The Journal of Organic Chemistry. 66: 7714-22. PMID 11701026 DOI: 10.1021/jo010593b  1
2000 Trost BM, Pinkerton AB. A new strategy for cyclopentenone synthesis. Organic Letters. 2: 1601-3. PMID 10841489  1
2000 Trost BM, Pinkerton AB. A Mechanistic Dichotomy Leading to a Ruthenium-Catalyzed cis-Addition for Stereoselective Formation of (Z)-Vinyl Bromides. Angewandte Chemie (International Ed. in English). 39: 360-362. PMID 10649409 DOI: 10.1002/(SICI)1521-3773(20000117)39:2<360::AID-ANIE360>3.0.CO;2-9  1
2000 Trost BM, Pinkerton AB, Kremzow D. A ruthenium-catalyzed pyrrolidine and piperidine synthesis [7] Journal of the American Chemical Society. 122: 12007-12008. DOI: 10.1021/ja003168t  1
2000 Trost BM, Pinkerton AB. A ru-catalyzed four-component coupling [6] Journal of the American Chemical Society. 122: 8081-8082. DOI: 10.1021/ja001656v  1
2000 Santos EC, Pinkerton AB, Kinkead SA, Hurlburt PK, Jasper SA, Sellers CW, Huffman JC, Todd LJ. Syntheses of nido-9,11-X2-7,8-C2B9H10/- anions (X-Cl, Br or I) and the synthesis and structural characterization of N(C2H5)4[commo- 3,3'-Co(4,7-Br2-3,1,2-CoC2B9H9)2] Polyhedron. 19: 1777-1781. DOI: 10.1016/S0277-5387(00)00461-7  1
2000 Trost BM, Pinkerton AB. Enhanced geometrical control in a Ru-catalyzed three component coupling Tetrahedron Letters. 41: 9627-9631.  1
1999 Trost BM, Pinkerton AB. A ruthenium-catalyzed alkylative cycloetherification [8] Journal of the American Chemical Society. 121: 10842-10843. DOI: 10.1021/ja9929537  1
1999 Trost BM, Pinkerton AB. A ruthenium-catalyzed two-component addition to form 1,3-dienes Journal of the American Chemical Society. 121: 4068-4069. DOI: 10.1021/ja990291f  1
1999 Trost BM, Pinkerton AB. A ruthenium-catalyzed three-component coupling to form E-vinyl chlorides [18] Journal of the American Chemical Society. 121: 1988-1989. DOI: 10.1021/ja984264l  1
1999 Seebach D, Pichota A, Beck AK, Pinkerton AB, Litz T, Karjalainen J, Gramlich V. Preparation of TADDOL derivatives for new applications Organic Letters. 1: 55-58.  1
1995 Miller RL, Pinkerton AB, Hurlburt PK, Abney KD. Extraction of cesium and strontium into hydrocarbon solvents using tetra-C-alkyl cobalt dicarbollide Solvent Extraction and Ion Exchange. 13: 813-827. DOI: 10.1080/07366299508918304  1
1994 Ashley KR, Ball JR, Pinkerton AB, Abney KD, Schroeder NC. Sorption behavior of pertechnetate on Reillex-HPQ anion exchange resin from nitric acid solution Solvent Extraction and Ion Exchange. 12: 239-259. DOI: 10.1080/07366299408918210  1
Show low-probability matches.