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Anthony Bruce Pinkerton - Publications

Affiliations: 
1996-2001 Chemistry Stanford University, Palo Alto, CA 
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Pinkerton AB, Peddibhotla S, Yamamoto F, Slosky L, Bai Y, Maloney PR, Hershberger P, Hedrick MP, Falter B, Ardecky RJ, Smith LH, Chung TD, Jackson M, Caron MG, Barak LS. Discovery of b-Arrestin Biased, Orally Bioavailable and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31390201 DOI: 10.1021/Acs.Jmedchem.9B00340  0.302
2019 Gardell SJ, Hopf M, Khan A, Dispagna M, Hampton Sessions E, Falter R, Kapoor N, Brooks J, Culver J, Petucci C, Ma CT, Cohen SE, Tanaka J, Burgos ES, Hirschi JS, ... ... Pinkerton AB, et al. Boosting NAD with a small molecule that activates NAMPT. Nature Communications. 10: 3241. PMID 31324777 DOI: 10.1038/S41467-019-11078-Z  0.356
2019 Feng Y, Sessions EH, Zhang F, Ban F, Placencio-Hickok V, Ma CT, Zeng FY, Pass I, Terry DB, Cadwell G, Bankston LA, Liddington RC, Chung TDY, Pinkerton AB, Sergienko E, et al. Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells. Cancer Letters. PMID 30771432 DOI: 10.1016/J.Canlet.2019.02.012  0.308
2018 Pinkerton AB, Sergienko E, Bravo Y, Dahl R, Ma CT, Sun Q, Jackson MR, Cosford NDP, Millán JL. Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor. Bioorganic & Medicinal Chemistry Letters. 28: 31-34. PMID 29174347 DOI: 10.1016/J.Bmcl.2017.11.024  0.306
2017 Villarino N, Signaevskaia L, van Niekerk J, Medal R, Kim H, Lahmy R, Scully K, Pinkerton A, Kim S, Lowy A, Itkin-Ansari P. A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer. Oncotarget. 8: 53154-53167. PMID 28881801 DOI: 10.18632/Oncotarget.18587  0.317
2017 Ziegler SG, Ferreira CR, MacFarlane EG, Riddle RC, Tomlinson RE, Chew EY, Martin L, Ma CT, Sergienko E, Pinkerton AB, Millán JL, Gahl WA, Dietz HC. Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase. Science Translational Medicine. 9. PMID 28592560 DOI: 10.1126/Scitranslmed.Aal1669  0.318
2017 Shiryaev SA, Farhy C, Pinto A, Huang CT, Simonetti N, Ngono AE, Dewing A, Shresta S, Pinkerton AB, Cieplak P, Strongin AY, Terskikh AV. Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists. Antiviral Research. PMID 28461069 DOI: 10.1016/J.Antiviral.2017.04.015  0.315
2017 Li J, Yakushi T, Parlati F, Mackinnon AL, Perez C, Ma Y, Carter KP, Colayco S, Magnuson G, Brown B, Nguyen K, Vasile S, Suyama E, Smith LH, Sergienko E, ... Pinkerton AB, et al. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nature Chemical Biology. PMID 28244987 DOI: 10.1038/Nchembio.2326  0.319
2015 Peddibhotla S, Fontaine P, Leung CK, Maloney P, Hershberger PM, Wang Y, Bousquet MS, Luesch H, Mangravita-Novo A, Pinkerton AB, Smith LH, Malany S, Choe K. Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes. Acs Chemical Biology. 10: 1871-9. PMID 25946346 DOI: 10.1021/Acschembio.5B00304  0.335
2015 Roemeling CAV, Caulfield TR, Radisky DC, Bok I, Marlow LA, Miller J, Sidiqi M, Pinkerton AB, Tan WW, Lane AL, Tun HW, Copland JA. Abstract 4459: Accelerated drug discovery platform yields synthesis of novel stearoyl-CoA desaturase 1 inhibitors that demonstrate anti-tumor efficacy in several models of aggressive cancer Cancer Research. 75: 4459-4459. DOI: 10.1158/1538-7445.Am2015-4459  0.303
2014 Hershberger PM, Hedrick MP, Peddibhotla S, Mangravita-Novo A, Gosalia P, Li Y, Gray W, Vicchiarelli M, Smith LH, Chung TD, Thomas JB, Caron MG, Pinkerton AB, Barak LS, Roth GP. Imidazole-derived agonists for the neurotensin 1 receptor. Bioorganic & Medicinal Chemistry Letters. 24: 262-7. PMID 24332089 DOI: 10.1016/J.Bmcl.2013.11.026  0.343
2013 Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, ... ... Pinkerton AB, et al. Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor. Acs Medicinal Chemistry Letters. 4: 846-851. PMID 24611085 DOI: 10.1021/Ml400176N  0.31
2013 Lee SH, Piran R, Keinan E, Pinkerton A, Levine F. Induction of β-cell replication by a synthetic HNF4α antagonist. Stem Cells (Dayton, Ohio). 31: 2396-407. PMID 23922283 DOI: 10.1002/Stem.1496  0.525
2013 Preuss J, Richardson AD, Pinkerton A, Hedrick M, Sergienko E, Rahlfs S, Becker K, Bode L. Identification and characterization of novel human glucose-6-phosphate dehydrogenase inhibitors. Journal of Biomolecular Screening. 18: 286-97. PMID 23023104 DOI: 10.1177/1087057112462131  0.304
2012 Maloney PR, Khan P, Hedrick M, Gosalia P, Milewski M, Li L, Roth GP, Sergienko E, Suyama E, Sugarman E, Nguyen K, Mehta A, Vasile S, Su Y, Stonich D, ... ... Pinkerton AB, et al. Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor. Bioorganic & Medicinal Chemistry Letters. 22: 6656-60. PMID 23010269 DOI: 10.1016/J.Bmcl.2012.08.105  0.32
2012 Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, et al. HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chemistry & Biology. 19: 806-18. PMID 22840769 DOI: 10.1016/J.Chembiol.2012.05.014  0.302
2012 Preuss J, Maloney P, Peddibhotla S, Hedrick MP, Hershberger P, Gosalia P, Milewski M, Li YL, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Mangravita-Novo A, ... ... Pinkerton AB, et al. Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro. Journal of Medicinal Chemistry. 55: 7262-72. PMID 22813531 DOI: 10.1021/Jm300833H  0.314
2012 Preuss J, Hedrick M, Sergienko E, Pinkerton A, Mangravita-Novo A, Smith L, Marx C, Fischer E, Jortzik E, Rahlfs S, Becker K, Bode L. High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase. Journal of Biomolecular Screening. 17: 738-51. PMID 22496096 DOI: 10.1177/1087057112442382  0.311
2012 Madiraju C, Matsuzawa S, Ardecky R, Pass I, Ngo T, Matsuzawa Y, Wimer C, Cuddy M, Diaz P, Ricardo C, Tamble C, Shu C, Pinkerton A, Sergienko E, Hassig C, et al. Discovery and Characterization of Chemical Inhibitors of UBC13. Blood. 120: 2950-2950. DOI: 10.1182/Blood.V120.21.2950.2950  0.335
2010 Herbert MR, Siegel DL, Staszewski L, Cayanan C, Banerjee U, Dhamija S, Anderson J, Fan A, Wang L, Rix P, Shiau AK, Rao TS, Noble SA, Heyman RA, Bischoff E, ... ... Pinkerton AB, et al. Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5. Bioorganic & Medicinal Chemistry Letters. 20: 5718-21. PMID 20801037 DOI: 10.1016/J.Bmcl.2010.08.014  0.312
2010 Trost BM, Pinkerton AB. ChemInform Abstract: A Ruthenium-Catalyzed Two-Component Addition to Form 1,3-Dienes. Cheminform. 30: no-no. DOI: 10.1002/chin.199933054  0.316
2007 Pinkerton AB, Lee TT, Hoffman TZ, Wang Y, Kahraman M, Cook TG, Severance D, Gahman TC, Noble SA, Shiau AK, Davis RL. Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 3562-9. PMID 17498954 DOI: 10.1016/J.Bmcl.2007.04.076  0.315
2007 Pinkerton AB, Huang D, Cube RV, Hutchinson JH, Struthers M, Ayala JM, Vicario PP, Patel SR, Wisniewski T, DeMartino JA, Vernier JM. Diaryl substituted pyrazoles as potent CCR2 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 17: 807-13. PMID 17088058 DOI: 10.1016/J.Bmcl.2006.10.060  0.31
2004 Pinkerton AB, Cube RV, Hutchinson JH, Rowe BA, Schaffhauser H, Zhao X, Daggett LP, Vernier JM. Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones. Bioorganic & Medicinal Chemistry Letters. 14: 5329-32. PMID 15454221 DOI: 10.1016/J.Bmcl.2004.08.020  0.317
2004 Trost BM, Chung CK, Pinkerton AB. Stereocontrolled total synthesis of (+)-streptazolin by a palladium-catalyzed reductive diyne cyclization. Angewandte Chemie (International Ed. in English). 43: 4327-9. PMID 15368383 DOI: 10.1002/Anie.200460058  0.597
2002 Trost BM, Pinkerton AB. Formation of vinyl halides via a ruthenium-catalyzed three-component coupling. Journal of the American Chemical Society. 124: 7376-89. PMID 12071746 DOI: 10.1021/Ja011426W  0.439
2002 Trost BM, Shen HC, Pinkerton AB. A synthesis of trisubstituted alkenes by a Ru-catalyzed addition. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 2341-9. PMID 12012418 DOI: 10.1002/1521-3765(20020517)8:10<2341::Aid-Chem2341>3.0.Co;2-A  0.517
2001 Trost BM, Pinkerton AB, Toste FD, Sperrle M. Synthesis of 1,1-disubstituted alkenes via a Ru-catalyzed addition. Journal of the American Chemical Society. 123: 12504-9. PMID 11741413 DOI: 10.1021/ja012009m  0.511
2001 Trost BM, Pinkerton AB, Seidel M. Ruthenium-catalyzed two-component addition to form 1,3-dienes: optimization, scope, applications, and mechanism. Journal of the American Chemical Society. 123: 12466-76. PMID 11741409 DOI: 10.1021/Ja011428G  0.383
2001 Trost BM, Toste FD, Pinkerton AB. Non-metathesis ruthenium-catalyzed C-C bond formation. Chemical Reviews. 101: 2067-96. PMID 11710241 DOI: 10.1021/Cr000666B  0.504
2001 Trost BM, Pinkerton AB. A three-component coupling approach to cyclopentanoids. The Journal of Organic Chemistry. 66: 7714-22. PMID 11701026 DOI: 10.1021/jo010593b  0.369
2000 Trost BM, Pinkerton AB. A new strategy for cyclopentenone synthesis. Organic Letters. 2: 1601-3. PMID 10841489 DOI: 10.1021/Ol005853A  0.445
2000 Trost BM, Pinkerton AB. A Mechanistic Dichotomy Leading to a Ruthenium-Catalyzed cis-Addition for Stereoselective Formation of (Z)-Vinyl Bromides. Angewandte Chemie (International Ed. in English). 39: 360-362. PMID 10649409 DOI: 10.1002/(Sici)1521-3773(20000117)39:2<360::Aid-Anie360>3.0.Co;2-9  0.391
2000 Trost BM, Pinkerton AB, Kremzow D. A ruthenium-catalyzed pyrrolidine and piperidine synthesis [7] Journal of the American Chemical Society. 122: 12007-12008. DOI: 10.1021/Ja003168T  0.365
2000 Trost BM, Pinkerton AB. A ru-catalyzed four-component coupling [6] Journal of the American Chemical Society. 122: 8081-8082. DOI: 10.1021/Ja001656V  0.39
2000 Trost BM, Pinkerton AB. Enhanced geometrical control in a Ru-catalyzed three component coupling Tetrahedron Letters. 41: 9627-9631. DOI: 10.1016/S0040-4039(00)01735-4  0.445
1999 Trost BM, Pinkerton AB. A ruthenium-catalyzed alkylative cycloetherification [8] Journal of the American Chemical Society. 121: 10842-10843. DOI: 10.1021/Ja9929537  0.433
1999 Trost BM, Pinkerton AB. A ruthenium-catalyzed two-component addition to form 1,3-dienes Journal of the American Chemical Society. 121: 4068-4069. DOI: 10.1021/Ja990291F  0.402
1999 Trost BM, Pinkerton AB. A ruthenium-catalyzed three-component coupling to form E-vinyl chlorides [18] Journal of the American Chemical Society. 121: 1988-1989. DOI: 10.1021/Ja984264L  0.395
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