Year |
Citation |
Score |
2020 |
Challa AP, Beam AL, Shen M, Peryea T, Lavieri RR, Lippmann ES, Aronoff DM. Machine learning on drug-specific data to predict small molecule teratogenicity. Reproductive Toxicology (Elmsford, N.Y.). PMID 32428651 DOI: 10.1016/J.Reprotox.2020.05.004 |
0.312 |
|
2017 |
Pulley JM, Shirey-Rice JK, Lavieri RR, Jerome RN, Zaleski NM, Aronoff DM, Bastarache L, Niu X, Holroyd KJ, Roden DM, Skaar EP, Niswender CM, Marnett LJ, Lindsley CW, Ekstrom LB, et al. Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics. Assay and Drug Development Technologies. PMID 28379727 DOI: 10.1089/Adt.2016.772 |
0.4 |
|
2015 |
Scott SA, Spencer CT, O'Reilly MC, Brown KA, Lavieri RR, Cho CH, Jung DI, Larock RC, Brown HA, Lindsley CW. Discovery of desketoraloxifene analogues as inhibitors of mammalian, Pseudomonas aeruginosa, and NAPE phospholipase D enzymes. Acs Chemical Biology. 10: 421-32. PMID 25384256 DOI: 10.1021/Cb500828M |
0.551 |
|
2011 |
Selvy PE, Lavieri RR, Lindsley CW, Brown HA. Phospholipase D: enzymology, functionality, and chemical modulation. Chemical Reviews. 111: 6064-119. PMID 21936578 DOI: 10.1021/Cr200296T |
0.448 |
|
2010 |
Lavieri RR, Scott SA, Selvy PE, Kim K, Jadhav S, Morrison RD, Daniels JS, Brown HA, Lindsley CW. Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor. Journal of Medicinal Chemistry. 53: 6706-19. PMID 20735042 DOI: 10.1021/Jm100814G |
0.58 |
|
2009 |
Lavieri R, Scott SA, Lewis JA, Selvy PE, Armstrong MD, Alex Brown H, Lindsley CW. Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity. Bioorganic & Medicinal Chemistry Letters. 19: 2240-3. PMID 19299128 DOI: 10.1016/J.Bmcl.2009.02.125 |
0.641 |
|
2009 |
Lewis JA, Scott SA, Lavieri R, Buck JR, Selvy PE, Stoops SL, Armstrong MD, Brown HA, Lindsley CW. Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity. Bioorganic & Medicinal Chemistry Letters. 19: 1916-20. PMID 19268584 DOI: 10.1016/J.Bmcl.2009.02.057 |
0.482 |
|
Show low-probability matches. |