| Year |
Citation |
Score |
| 1999 |
Yuann JM, Liu KJ, Hamilton JW, Wetterhahn KE. In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium-DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of osteogenic disorder shionogi rats following treatment with chromium(VI). Carcinogenesis. 20: 1267-75. PMID 10383900 DOI: 10.1093/Carcin/20.7.1267 |
0.522 |
|
| 1997 |
Wilker JJ, Wetterhahn KE, Lippard SJ. Methyl Transfer to Mercury Thiolates: Effects of Coordination Number and Ligand Dissociation. Inorganic Chemistry. 36: 2079-2083. PMID 11669826 DOI: 10.1021/Ic961178I |
0.5 |
|
| 1997 |
Sugden KD, Wetterhahn KE. Direct and hydrogen peroxide-induced chromium(V) oxidation of deoxyribose in single-stranded and double-stranded calf thymus DNA Chemical Research in Toxicology. 10: 1397-1406. PMID 9437531 DOI: 10.1021/tx970135r |
0.317 |
|
| 1996 |
Costa M, Zhitkovich A, Gargas M, Paustenbach D, Finley B, Kuykendall J, Billings R, Carlson TJ, Wetterhahn K, Xu J, Patierno S, Bogdanffy M. Interlaboratory validation of a new assay for DNA-protein crosslinks. Mutation Research. 369: 13-21. PMID 8700178 DOI: 10.1016/S0165-1218(96)90043-9 |
0.385 |
|
| 1995 |
Stearns DM, Kennedy LJ, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Reduction of chromium(VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro. Biochemistry. 34: 910-9. PMID 7827049 DOI: 10.1021/Bi00003A025 |
0.352 |
|
| 1994 |
Alcedo JA, Misra M, Hamilton JW, Wetterhahn KE. The genotoxic carcinogen chromium(VI) alters the metal-inducible expression but not the basal expression of the metallothionein gene in vivo. Carcinogenesis. 15: 1089-92. PMID 8200074 DOI: 10.1093/Carcin/15.5.1089 |
0.542 |
|
| 1994 |
Misra M, Alcedo JA, Wetterhahn KE. Two pathways for chromium(VI)-induced DNA damage in 14 day chick embryos: Cr-DNA binding in liver and 8-oxo-2'-deoxyguanosine in red blood cells. Carcinogenesis. 15: 2911-7. PMID 8001255 |
0.388 |
|
| 1994 |
Stearns DM, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Chromium(VI) reduction by ascorbate: role of reactive intermediates in DNA damage in vitro. Environmental Health Perspectives. 102: 21-5. PMID 7843100 DOI: 10.1289/Ehp.94102S321 |
0.366 |
|
| 1992 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Alcedo JA, Wetterhahn KE. Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes. Archives of Biochemistry and Biophysics. 298: 96-104. PMID 1524447 DOI: 10.1016/0003-9861(92)90099-I |
0.549 |
|
| 1991 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Alcedo JA, Wetterhahn KE. Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription. Archives of Biochemistry and Biophysics. 289: 387-92. PMID 1898078 DOI: 10.1016/0003-9861(91)90428-L |
0.538 |
|
| 1991 |
Borges KM, Boswell JS, Liebross RH, Wetterhahn KE. Activation of chromium(VI) by thiols results in chromium(V) formation, chromium binding to DNA and altered DNA conformation. Carcinogenesis. 12: 551-61. PMID 1849467 |
0.357 |
|
| 1991 |
Borges KM, Wetterhahn KE. Chromium bound to DNA alters cleavage by restriction endonucleases. Chemical Research in Toxicology. 4: 638-41. PMID 1666962 |
0.329 |
|
| 1991 |
Aiyar J, Berkovits HJ, Floyd RA, Wetterhahn KE. Reaction of chromium(VI) with glutathione or with hydrogen peroxide: identification of reactive intermediates and their role in chromium(VI)-induced DNA damage. Environmental Health Perspectives. 92: 53-62. PMID 1657590 DOI: 10.1289/ehp.919253 |
0.351 |
|
| 1989 |
Borges KM, Wetterhahn KE. Chromium cross-links glutathione and cysteine to DNA. Carcinogenesis. 10: 2165-8. PMID 2805236 |
0.358 |
|
| 1989 |
Hamilton JW, Wetterhahn KE. Differential effects of chromium(VI) on constitutive and inducible gene expression in chick embryo liver in vivo and correlation with chromium(VI)-induced DNA damage Molecular Carcinogenesis. 2: 274-286. PMID 2604865 DOI: 10.1002/Mc.2940020508 |
0.619 |
|
| 1989 |
Wetterhahn KE, Hamilton JW. Molecular basis of hexavalent chromium carcinogenicity: effect on gene expression. The Science of the Total Environment. 86: 113-29. PMID 2602931 DOI: 10.1016/0048-9697(89)90199-X |
0.628 |
|
| 1989 |
Wetterhahn KE, Hamilton JW, Aiyar J, Borges KM, Floyd R. Mechanism of chromium(VI) carcinogenesis. Reactive intermediates and effect on gene expression. Biological Trace Element Research. 21: 405-11. PMID 2484620 DOI: 10.1007/Bf02917282 |
0.597 |
|
| 1989 |
Standeven AM, Wetterhahn KE. Chromium(VI) Toxicity: Uptake, Reduction, and DNA Damage Journal of the American College of Toxicology. 8: 1275-1283. DOI: 10.3109/10915818909009118 |
0.357 |
|
| 1988 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Wetterhahn KE. Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem Biochemical Journal. 255: 267-275. PMID 3196319 DOI: 10.1042/Bj2570936 |
0.529 |
|
| 1986 |
Hamilton JW, Wetterhahn KE. Chromium (vi)-induced dna damage in chick embryo liver and blood cells in vivo Carcinogenesis. 7: 2085-2088. PMID 3779902 DOI: 10.1093/Carcin/7.12.2085 |
0.574 |
|
| 1985 |
Cupo DY, Wetterhahn KE. Repair of chromate-induced DNA damage in chick embryo hepatocytes. Carcinogenesis. 5: 1705-8. PMID 6499121 DOI: 10.1093/CARCIN/5.12.1705 |
0.416 |
|
| 1985 |
Cupo DY, Wetterhahn KE. Modification of chromium(VI)-induced DNA damage by glutathione and cytochromes P-450 in chicken embryo hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 82: 6755-9. PMID 3863126 DOI: 10.1073/PNAS.82.20.6755 |
0.394 |
|
| 1985 |
Cupo DY, Wetterhahn KE. Binding of chromium to chromatin and DNA from liver and kidney of rats treated with sodium dichromate and chromium(III) chloride in vivo. Cancer Research. 45: 1146-51. PMID 2578874 |
0.372 |
|
| 1984 |
Ciccarelli RB, Wetterhahn KE. Molecular basis for the activity of nickel. Iarc Scientific Publications. 201-13. PMID 6085326 |
0.364 |
|
| 1983 |
Tsapakos MJ, Hampton TH, Sinclair PR, Sinclair JF, Bement WJ, Wetterhahn KE. The carcinogen chromate causes DNA damage and inhibits drug-mediated induction of porphyrin accumulation and glucuronidation in chick embryo hepatocytes. Carcinogenesis. 4: 959-66. PMID 6872154 DOI: 10.1093/CARCIN/4.8.959 |
0.413 |
|
| 1983 |
Tsapakos MJ, Hampton TH, Wetterhahn KE. Chromium(VI)-induced DNA lesions and chromium distribution in rat kidney, liver, and lung. Cancer Research. 43: 5662-7. PMID 6640521 |
0.357 |
|
| 1983 |
Tsapakos MJ, Wetterhahn KE. The interaction of chromium with nucleic acids. Chemico-Biological Interactions. 46: 265-77. PMID 6627506 DOI: 10.1016/0009-2797(83)90034-0 |
0.352 |
|
| 1982 |
Ciccarelli RB, Wetterhahn KE. Nickel distribution and DNA lesions induced in rat tissues by the carcinogen nickel carbonate. Cancer Research. 42: 3544-9. PMID 7105030 |
0.354 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1993 |
Hneihen AS, Standeven AM, Wetterhahn KE. Differential binding of chromium(VI) and chromium(III) complexes to salmon sperm nuclei and nuclear DNA and isolated calf thymus DNA. Carcinogenesis. 14: 1795-803. PMID 8403202 |
0.29 |
|
| 1989 |
Aiyar J, Borges KM, Floyd RA, Wetterhahn KE. Role of chromium(V), glutathione thiyl radical and hydroxyl radical intermediates in Chromium(VI)‐induced DNA Damage Toxicological & Environmental Chemistry. 22: 135-148. DOI: 10.1080/02772248909357432 |
0.287 |
|
| 1984 |
Ciccarelli RB, Wetterhahn KE. Nickel-bound chromatin, nucleic acids, and nuclear proteins from kidney and liver of rats treated with nickel carbonate in vivo. Cancer Research. 44: 3892-7. PMID 6204748 |
0.287 |
|
| 1985 |
Ciccarelli RB, Wetterhahn KE. In vitro interaction of 63-nickel(II) with chromatin and DNA from rat kidney and liver nuclei. Chemico-Biological Interactions. 52: 347-60. PMID 3971472 DOI: 10.1016/0009-2797(85)90029-8 |
0.284 |
|
| 1992 |
Liebross RH, Wetterhahn KE. In vivo formation of chromium(V) in chick embryo liver and red blood cells. Carcinogenesis. 13: 2113-20. PMID 1330350 |
0.266 |
|
| 1992 |
Standeven AM, Wetterhahn KE. Ascorbate is the principal reductant of chromium(VI) in rat lung ultrafiltrates and cytosols, and mediates chromium-DNA binding in vitro. Carcinogenesis. 13: 1319-24. PMID 1499083 |
0.26 |
|
| 1990 |
Aiyar J, Berkovits HJ, Floyd RA, Wetterhahn KE. Reaction of chromium (VI) with hydrogen peroxide in the presence of glutathione: reactive intermediates and resulting DNA damage. Chemical Research in Toxicology. 3: 595-603. PMID 1966470 DOI: 10.1021/tx00018a016 |
0.258 |
|
| 1992 |
Aiyar J, De Flora S, Wetterhahn KE. Reduction of chromium(VI) to chromium(V) by rat liver cytosolic and microsomal fractions: is DT-diaphorase involved? Carcinogenesis. 13: 1159-66. PMID 1379126 |
0.254 |
|
| 1997 |
Stearns DM, Wetterhahn KE. Intermediates produced in the reaction of chromium(VI) with dehydroascorbate cause single-strand breaks in plasmid DNA. Chemical Research in Toxicology. 10: 271-8. PMID 9084906 DOI: 10.1021/tx9601521 |
0.249 |
|
| 1998 |
Dubrovskaya VA, Wetterhahn KE. Effects of Cr(VI) on the expression of the oxidative stress genes in human lung cells. Carcinogenesis. 19: 1401-7. PMID 9744536 DOI: 10.1093/carcin/19.8.1401 |
0.249 |
|
| 1991 |
Standeven AM, Wetterhahn KE. Ascorbate is the principal reductant of chromium (VI) in rat liver and kidney ultrafiltrates. Carcinogenesis. 12: 1733-7. PMID 1893533 |
0.236 |
|
| 1991 |
Standeven AM, Wetterhahn KE. Possible role of glutathione in chromium(VI) metabolism and toxicity in rats. Pharmacology & Toxicology. 68: 469-76. PMID 1891442 |
0.234 |
|
| 1996 |
Sugden KD, Wetterhahn KE. EPR Evidence for Chromium(V) Binding to Phosphate and Pyrophosphate: Implications for Chromium(V)-DNA Interactions. Inorganic Chemistry. 35: 3727-3728. PMID 11666556 |
0.231 |
|
| 1996 |
Barchowsky A, Dudek EJ, Treadwell MD, Wetterhahn KE. Arsenic induces oxidant stress and NF-κB activation in cultured aortic endothelial cells Free Radical Biology and Medicine. 21: 783-790. PMID 8902524 DOI: 10.1016/0891-5849(96)00174-8 |
0.218 |
|
| 1998 |
Shumilla JA, Wetterhahn KE, Barchowsky A. Inhibition of NF-κB binding to DNA by chromium, cadmium, mercury, zinc, and arsenite in vitro: Evidence of a thiol mechanism Archives of Biochemistry and Biophysics. 349: 356-362. PMID 9448725 DOI: 10.1006/Abbi.1997.0470 |
0.207 |
|
| 1996 |
Sugden KD, Wetterhahn KE. Reaction of Chromium(V) with the EPR Spin Traps 5,5-Dimethylpyrroline N-Oxide and Phenyl-N-tert-butylnitrone Resulting in Direct Oxidation Inorganic Chemistry. 35: 651-657. |
0.194 |
|
| 1984 |
Floro NA, Wetterhahn KE. Effect of chromium(III) on poly(dG-dC) conformation. Biochemical and Biophysical Research Communications. 124: 106-13. PMID 6497874 DOI: 10.1016/0006-291X(84)90923-9 |
0.186 |
|
| 1991 |
Standeven AM, Wetterhahn KE. Tissue-specific changes in glutathione and cysteine after buthionine sulfoximine treatment of rats and the potential for artifacts in thiol levels resulting from tissue preparation. Toxicology and Applied Pharmacology. 107: 269-84. PMID 1994510 |
0.185 |
|
| 1996 |
Sugden KD, Wetterhahn KE. Identification of the oxidized products formed upon reaction of Chromium(V) with thymidine nucleotides Journal of the American Chemical Society. 118: 10811-10818. DOI: 10.1021/ja962428x |
0.177 |
|
| 1996 |
Brauer SL, Hneihen AS, McBride JS, Wetterhahn KE. Chromium(VI) Forms Thiolate Complexes with gamma-Glutamylcysteine, N-Acetylcysteine, Cysteine, and the Methyl Ester of N-Acetylcysteine. Inorganic Chemistry. 35: 373-381. PMID 11666218 |
0.175 |
|
| 1995 |
Stearns DM, Wise JP, Patierno SR, Wetterhahn KE. Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1643-8. PMID 8529845 |
0.173 |
|
| 1994 |
Wise JP, Stearns DM, Wetterhahn KE, Patierno SR. Cell-enhanced dissolution of carcinogenic lead chromate particles: the role of individual dissolution products in clastogenesis. Carcinogenesis. 15: 2249-54. PMID 7955062 DOI: 10.1093/Carcin/15.10.2249 |
0.17 |
|
| 1989 |
Rossi SC, Wetterhahn KE. Chromium(V) is produced upon reduction of chromate by mitochondrial electron transport chain complexes. Carcinogenesis. 10: 913-20. PMID 2539917 |
0.165 |
|
| 1995 |
Stearns DM, Wise JP, Patierno SR, Wetterhahn KE. Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells. The Faseb Journal. 9: 1643-1648. DOI: 10.1096/Fasebj.9.15.8529845 |
0.164 |
|
| 1995 |
Stearns DM, Belbruno JJ, Wetterhahn KE. A prediction of chromium(III) accumulation in humans from chromium dietary supplements. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1650-7. PMID 8529846 |
0.163 |
|
| 1994 |
Stearns DM, Wetterhahn KE. Reaction of chromium(VI) with ascorbate produces chromium(V), chromium(IV), and carbon-based radicals. Chemical Research in Toxicology. 7: 219-30. PMID 8199312 |
0.154 |
|
| 1988 |
Rossi SC, Gorman N, Wetterhahn KE. Mitochondrial reduction of the carcinogen chromate: formation of chromium(V). Chemical Research in Toxicology. 1: 101-7. PMID 2979716 |
0.141 |
|
| 1993 |
Stearns DM, Wetterhahn KE. Reduction of carcinogenic chromium(VI) by dehydroascorbate and its decomposition products. Journal of Inorganic Biochemistry. 51: 430. DOI: 10.1016/0162-0134(93)85459-L |
0.119 |
|
| 1990 |
Liebross RH, Wetterhahn KE. In vivo formation of chromium(V) in chick embryo red blood cells. Chemical Research in Toxicology. 3: 401-3. PMID 1966788 |
0.119 |
|
| 1990 |
Alcedo JA, Wetterhahn KE. Chromium toxicity and carcinogenesis. International Review of Experimental Pathology. 31: 85-108. PMID 2292475 |
0.116 |
|
| 1986 |
CONNETT PH, WETTERHAHN KE. ChemInform Abstract: Reaction of Chromium(VI) with Thiols: pH Dependence of Chromium(VI) Thio Ester Formation Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198632247 |
0.104 |
|
| 1986 |
Connett PH, Wetterhahn KE. Reaction of chromium(VI) with thiols: pH dependence of chromium(VI) thio ester formation Journal of the American Chemical Society. 108: 1842-1847. DOI: 10.1021/JA00268A022 |
0.104 |
|
| 1993 |
Wetterhahn K, Stearns D, Giangrande P, Phieffer L, Courtney K. The role of ascorbate in metabolism and genotoxicity of chromium(VI). Journal of Inorganic Biochemistry. 51: 551. DOI: 10.1016/0162-0134(93)85577-U |
0.097 |
|
| 1991 |
Standeven AM, Wetterhahn KE. Is there a role for reactive oxygen species in the mechanism of chromium(VI) carcinogenesis? Chemical Research in Toxicology. 4: 616-25. PMID 1807444 |
0.093 |
|
| 1991 |
Brauer SL, Wetterhahn KE. Chromium(VI) forms a thiolate complex with glutathione Journal of the American Chemical Society. 113: 3001-3007. DOI: 10.1021/JA00008A031 |
0.089 |
|
| 1985 |
CONNETT PH, WETTERHAHN KE. ChemInform Abstract: IN VITRO REACTION OF THE CARCINOGEN CHROMATE WITH CELLULAR THIOLS AND CARBOXYLIC ACIDS Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198544246 |
0.076 |
|
| 1985 |
Connett PH, Wetterhahn KE. In vitro reaction of the carcinogen chromate with cellular thiols and carboxylic acids Journal of the American Chemical Society. 107: 4282-4288. DOI: 10.1021/JA00300A035 |
0.076 |
|
| 1992 |
Wetterhahn KE, Demple B, Kulesz-Martin M, Copeland ES. Workshop report from the Division of Research Grants, National Institutes of Health. Metal carcinogenesis--a Chemical Pathology Study Section Workshop. Cancer Research. 52: 4058-63. PMID 1617683 |
0.063 |
|
| Hide low-probability matches. |
