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Jon C. Lorenz, Ph.D. - Publications

Affiliations: 
2002 Colorado State University, Fort Collins, CO 
Area:
synthesis of natural products
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 DeCroos P, Han ZS, Sidhu K, Lorenz J, Nummy L, Byrne D, Qu B, Xu Y, Wu L, Lee H, Roschangar F, Song JJ, Senanayake CH. Development of a Large-Scale Asymmetric Process fortert-Butanesulfinamide Organic Process Research & Development. 23: 263-268. DOI: 10.1021/Acs.Oprd.8B00399  0.347
2018 Sieber JD, Rodriguez S, Frutos R, Buono F, Zhang Y, Li N, Qu B, Premasiri A, Li Z, Han ZS, Xu Y, Byrne D, Haddad N, Lorenz J, Grinberg N, et al. Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative in High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation. The Journal of Organic Chemistry. PMID 29323903 DOI: 10.1021/Acs.Joc.7B03022  0.386
2017 Mulder JA, Gao J, Fandrick KR, Zeng X, Desrosiers J, Patel ND, Li Z, Rodriguez S, Lorenz JC, Wang J, Ma S, Fandrick DR, Grinberg N, Lee H, Bosanac T, et al. Early Development Scale-Up of a Structurally-Challenging 5-Lipoxygenase Activating Protein (FLAP) Inhibitor Organic Process Research & Development. 21: 1427-1434. DOI: 10.1021/Acs.Oprd.7B00202  0.388
2016 Wei X, Qu B, Zeng X, Savoie J, Fandrick KR, Desrosiers JN, Tcyrulnikov S, Marsini MA, Buono FG, Li Z, Yang BS, Tang W, Haddad N, Gutierrez O, Wang J, ... ... Lorenz JC, et al. Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor. Journal of the American Chemical Society. PMID 27794616 DOI: 10.1021/Jacs.6B09764  0.305
2016 Zhang Y, Wu JP, Li G, Fandrick KR, Gao J, Tan Z, Johnson J, Li W, Sanyal S, Wang J, Sun X, Lorenz JC, Rodriguez S, Reeves JT, Grinberg N, et al. An Enantioselective Synthesis of an 11-beta-HSD-1 Inhibitor via an Asymmetric Methallylation Catalyzed by (S)-3,3'-F2-BINOL. The Journal of Organic Chemistry. PMID 26909738 DOI: 10.1021/Acs.Joc.6B00189  0.31
2016 Patel ND, Zhang Y, Gao J, Sidhu K, Lorenz JC, Fandrick KR, Mulder JA, Herbage MA, Li Z, Ma S, Lee H, Grinberg N, Song JJ, Busacca CA, Yee NK, et al. Development of an Efficient Synthesis of (2-Aminopyrimidin-5-yl) Boronic Acid Organic Process Research and Development. 20: 95-99. DOI: 10.1021/Acs.Oprd.5B00360  0.388
2016 Wu JP, Saha AK, Haddad N, Busacca CA, Lorenz JC, Lee H, Senanayake CH. Simple N-Heterocyclic Carbenes as Ligands in Ullmann-Type Ether and Thioether Formations Advanced Synthesis and Catalysis. 358: 1924-1928. DOI: 10.1002/Adsc.201600316  0.306
2015 Fandrick KR, Li W, Zhang Y, Tang W, Gao J, Rodriguez S, Patel ND, Reeves DC, Wu JP, Sanyal S, Gonnella N, Qu B, Haddad N, Lorenz JC, Sidhu K, et al. Concise and Practical Asymmetric Synthesis of a Challenging Atropisomeric HIV Integrase Inhibitor. Angewandte Chemie (International Ed. in English). 54: 7144-8. PMID 25939331 DOI: 10.1002/Anie.201501575  0.305
2015 Haddad N, Qu B, Lee H, Lorenz J, Varsolona R, Kapadia S, Sarvestani M, Feng X, Busacca CA, Hebrault D, Rea S, Schellekens L, Senanayake CH. PAT application in the expedited development of a three-step, one-stage synthesis of the dipeptide intermediate of HCV protease inhibitor faldaprevir Organic Process Research and Development. 19: 132-138. DOI: 10.1021/Op400285Y  0.353
2014 Buono FG, Eriksson MC, Yang BS, Kapadia SR, Lee H, Brazzillo J, Lorenz JC, Nummy L, Busacca CA, Yee N, Senanayake C. Development of multikilogram continuous flow cyclopropanation of N -benzylmaleimide through kinetic analysis Organic Process Research and Development. 18: 1527-1534. DOI: 10.1021/Op500263M  0.433
2013 Reeves JT, Fandrick DR, Tan Z, Song JJ, Rodriguez S, Qu B, Kim S, Niemeier O, Li Z, Byrne D, Campbell S, Chitroda A, DeCroos P, Fachinger T, Fuchs V, ... ... Lorenz JC, et al. Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4. The Journal of Organic Chemistry. 78: 3616-35. PMID 23544738 DOI: 10.1021/Jo400079Z  0.477
2013 Zhang Y, Li N, Qu B, Ma S, Lee H, Gonnella NC, Gao J, Li W, Tan Z, Reeves JT, Wang J, Lorenz JC, Li G, Reeves DC, Premasiri A, et al. Asymmetric methallylation of ketones catalyzed by a highly active organocatalyst 3,3'-F2-BINOL. Organic Letters. 15: 1710-3. PMID 23527954 DOI: 10.1021/Ol400498A  0.313
2013 Li W, Rodriguez S, Duran A, Sun X, Tang W, Premasiri A, Wang J, Sidhu K, Patel ND, Savoie J, Qu B, Lee H, Haddad N, Lorenz JC, Nummy L, et al. The P-chiral phosphane ligand (MeO-BIBOP) for efficient and practical large-scale Rh-catalyzed asymmetric hydrogenation of N-acetyl enamides with high TONs Organic Process Research and Development. 17: 1061-1065. DOI: 10.1021/Op400055Z  0.385
2012 Latli B, Hrapchak M, Lorenz JC, Busacca CA, Senanayake C. Synthesis of a potent cathepsin s inhibitor labeled with deuterium and carbon-14. Current Radiopharmaceuticals. 5: 314-7. PMID 22724423 DOI: 10.2174/1874471011205040314  0.369
2012 Li W, Gao JJ, Lorenz JC, Xu J, Johnson J, Ma S, Lee H, Grinberg N, Busacca CA, Lu B, Senanayake CH. Process development and pilot-plant synthesis of (S)-tert-butyl 1-oxo-1-(1-(pyridin-2-yl)cyclopropylamino)propan-2-ylcarbamate: Studies on the scale-up of Kulinkovich-Szymoniak cyclopropanation Organic Process Research and Development. 16: 836-839. DOI: 10.1021/Op300059B  0.415
2012 Qu B, Haddad N, Rodriguez S, Lee H, Ma S, Zeng X, Reeves DC, Sidhu KPS, Lorenz JC, Grinberg N, Busacca CA, Krishnamurthy D, Senanayake CH. Chelation controlled reductive amination of cyclic ketones to trans-4-methoxycyclohexylamines: 9-BBN reduction mediated with FeCl 3 Tetrahedron Letters. 53: 1982-1986. DOI: 10.1016/J.Tetlet.2012.02.023  0.34
2010 Lorenz JC, Busacca CA, Feng X, Grinberg N, Haddad N, Johnson J, Kapadia S, Lee H, Saha A, Sarvestani M, Spinelli EM, Varsolona R, Wei X, Zeng X, Senanayake CH. Large-scale asymmetric synthesis of a cathepsin S inhibitor. The Journal of Organic Chemistry. 75: 1155-61. PMID 20102230 DOI: 10.1021/Jo9022809  0.34
2009 Qu B, Haddad N, Han ZS, Rodriguez S, Lorenz JC, Grinberg N, Lee H, Busacca CA, Krishnamurthy D, Senanayake CH. Palladium-catalyzed aminocarbonylation of heteroaryl halides using di-tert-butylphosphinoferrocene Tetrahedron Letters. 50: 6126-6129. DOI: 10.1016/J.Tetlet.2009.08.065  0.334
2008 Busacca CA, Raju R, Grinberg N, Haddad N, James-Jones P, Lee H, Lorenz JC, Saha A, Senanayake CH. Reduction of tertiary phosphine oxides with DIBAL-H. The Journal of Organic Chemistry. 73: 1524-31. PMID 18197688 DOI: 10.1021/Jo7024064  0.351
2008 Busacca CA, Lorenz JC, Grinberg N, Haddad N, Lee H, Li Z, Liang M, Reeves D, Saha A, Varsolona R, Senanayake CH. Asymmetric hydrogenation of unsaturated ureas with the BIPI ligands. Organic Letters. 10: 341-4. PMID 18095698 DOI: 10.1021/Ol7028542  0.379
2008 Busacca CA, Cerreta M, Dong Y, Eriksson MC, Farina V, Feng X, Kim JY, Lorenz JC, Sarvestani M, Simpson R, Varsolona R, Vitous J, Campbell SJ, Davis MS, Jones PJ, et al. Development of a pilot-plant process for a nevirapine analogue HIV NNRT inhibitor Organic Process Research and Development. 12: 603-613. DOI: 10.1021/Op8000756  0.368
2007 Wei X, Lorenz JC, Kapadia S, Saha A, Haddad N, Busacca CA, Senanayake CH. Tandem Pd(II)-catalyzed vinyl ether exchange-Claisen rearrangement as a facile approach to gamma,delta-unsaturated aldehydes. The Journal of Organic Chemistry. 72: 4250-3. PMID 17447813 DOI: 10.1021/Jo062548F  0.354
2005 Lorenz JC, Frohn M, Zhou X, Zhang JR, Tang Y, Burke C, Shi Y. Transition state studies on the dioxirane-mediated asymmetric epoxidation via kinetic resolution and desymmetrization. The Journal of Organic Chemistry. 70: 2904-11. PMID 15822948 DOI: 10.1021/Jo048217P  0.528
2004 Busacca CA, Grossbach D, Campbell SJ, Dong Y, Eriksson MC, Harris RE, Jones PJ, Kim JY, Lorenz JC, McKellop KB, O'Brien EM, Qiu F, Simpson RD, Smith L, So RC, et al. Electronic control of chiral quaternary center creation in the intramolecular asymmetric heck reaction. The Journal of Organic Chemistry. 69: 5187-95. PMID 15287760 DOI: 10.1021/Jo049448Z  0.412
2004 Lorenz JC, Long J, Yang Z, Xue S, Xie Y, Shi Y. A novel class of tunable zinc reagents (RXZnCH2Y) for efficient cyclopropanation of olefins. The Journal of Organic Chemistry. 69: 327-34. PMID 14725443 DOI: 10.1021/Jo030312V  0.573
1998 Yang Z, Lorenz JC, Shi Y. Exploring new reactive species for cyclopropanation Tetrahedron Letters. 39: 8621-8624. DOI: 10.1016/S0040-4039(98)01954-6  0.524
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