Mihirbaran Mandal, Ph.D. - Publications

Affiliations: 
2002 University of Southern California, Los Angeles, CA, United States 
Area:
Fluorine chemistry, physical organic chemistry, organic synthesis, hydrocarbon chemistry

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Mandal M, Wu Y, Misiaszek J, Li G, Buevich AV, Caldwell JP, Liu X, Mazzola RD, Orth P, Strickland C, Voigt JH, Wang H, Zhu Z, Chen X, Grzelak M, et al. Structure-Based Design of an Iminoheterocyclic beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in non-Human Primates. Journal of Medicinal Chemistry. PMID 26937601 DOI: 10.1021/acs.jmedchem.5b01995  0.96
2012 Huang X, Zhou W, Liu X, Li H, Sun G, Mandal M, Vicarel M, Zhu X, Bennett C, McCraken T, Pissarnitski D, Zhao Z, Cole D, Gallo G, Zhu Z, et al. Synthesis and SAR Studies of Fused Oxadiazines as γ-Secretase Modulators for Treatment of Alzheimer's Disease. Acs Medicinal Chemistry Letters. 3: 931-5. PMID 24900409 DOI: 10.1021/ml300209g  0.96
2012 Mandal M, Zhu Z, Cumming JN, Liu X, Strickland C, Mazzola RD, Caldwell JP, Leach P, Grzelak M, Hyde L, Zhang Q, Terracina G, Zhang L, Chen X, Kuvelkar R, et al. Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation. Journal of Medicinal Chemistry. 55: 9331-45. PMID 22989333 DOI: 10.1021/jm301039c  0.96
2012 Mandal M, Lavey C, Buevich AV, Zhu Z, Stamford AW, Liu X. On the power of super acid - Iodination of aromatic ring in the presence of imidazole moiety of the potent gamma secretase modulators (GSM) en route to tritium labeling Tetrahedron Letters. 53: 1725-1727. DOI: 10.1016/j.tetlet.2012.01.085  0.96
2011 Qin J, Dhondi P, Huang X, Mandal M, Zhao Z, Pissarnitski D, Zhou W, Aslanian R, Zhu Z, Greenlee W, Clader J, Zhang L, Cohen-Williams M, Jones N, Hyde L, et al. Discovery of fused 5,6-bicyclic heterocycles as γ-secretase modulators. Bioorganic & Medicinal Chemistry Letters. 21: 664-9. PMID 21195610 DOI: 10.1016/j.bmcl.2010.12.012  0.96
2010 Oskarsson T, Nagorny P, Krauss IJ, Perez L, Mandal M, Yang G, Ouerfelli O, Xiao D, Moore MA, Massagué J, Danishefsky SJ. Diverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analog. Journal of the American Chemical Society. 132: 3224-8. PMID 20155906 DOI: 10.1021/ja9101503  0.96
2007 Krauss IJ, Mandal M, Danishefsky SJ. Total synthesis of (+)-isomigrastatin. Angewandte Chemie (International Ed. in English). 46: 5576-9. PMID 17583888 DOI: 10.1002/anie.200701837  0.96
2006 Prakash GK, Panja C, Vaghoo H, Surampudi V, Kultyshev R, Mandal M, Rasul G, Mathew T, Olah GA. Facile synthesis of TMS-protected trifluoromethylated alcohols using trifluoromethyltrimethylsilane (TMSCF3) and various nucleophilic catalysts in DMF. The Journal of Organic Chemistry. 71: 6806-13. PMID 16930030 DOI: 10.1021/jo060835d  0.96
2005 Mandal M, Yun H, Dudley GB, Lin S, Tan DS, Danishefsky SJ. Total synthesis of guanacastepene a: a route to enantiomeric control. The Journal of Organic Chemistry. 70: 10619-37. PMID 16355979 DOI: 10.1021/jo051470k  0.96
2005 Ma J, Natarajan R, LaPage J, Lanting L, Kim N, Becerra D, Clemmons B, Nast CC, Surya Prakash GK, Mandal M, Adler SG. 12/15-lipoxygenase inhibitors in diabetic nephropathy in the rat. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 72: 13-20. PMID 15589395 DOI: 10.1016/j.plefa.2004.06.004  0.96
2005 Prakash GKS, Mathew T, Mandal M, Farnia M, Olah GA. Aroylation of aromatics with arylcarboxylic acids over Nafion-H (polymeric perfluoroalkanesulfonic acid), an environmentally friendly solid acid catalyst Arkivoc. 2005: 103-110.  0.96
2004 Dudkin VY, Orlova M, Geng X, Mandal M, Olson WC, Danishefsky SJ. Toward fully synthetic carbohydrate-based HIV antigen design: on the critical role of bivalency. Journal of the American Chemical Society. 126: 9560-2. PMID 15291558 DOI: 10.1021/ja047720g  0.96
2004 Geng X, Dudkin VY, Mandal M, Danishefsky SJ. In pursuit of carbohydrate-based HIV vaccines, part 2: The total synthesis of high-mannose-type gp120 fragments--evaluation of strategies directed to maximal convergence. Angewandte Chemie (International Ed. in English). 43: 2562-5. PMID 15127453 DOI: 10.1002/anie.200353626  0.96
2004 Mandal M, Danishefsky SJ. Probing the formation and chemistry of enoxyoxirane derivatives in the C-ring en route to guanacastepene Tetrahedron Letters. 45: 3831-3833. DOI: 10.1016/j.tetlet.2004.02.162  0.96
2004 Mandal M, Danishefsky SJ. Probing competitive pathways in building a hydroazulene moiety by reductive cyclization Tetrahedron Letters. 45: 3827-3829. DOI: 10.1016/j.tetlet.2004.02.161  0.96
2003 Prakash GKS, Mandal M, Panja C, Mathew T, Olah GA. Preparation of TMS protected trifluoromethylated alcohols using trimethylamine N-oxide and trifluoromethyltrimethylsilane (TMSCHF3) Journal of Fluorine Chemistry. 123: 61-63. DOI: 10.1016/S0022-1139(03)00104-0  0.96
2002 Prakash GK, Mandal M. Stereoselective synthesis of trifluoromethylated vicinal ethylenediamines with alpha-amino N-tert-butanesulfinimines and TMSCF3. Journal of the American Chemical Society. 124: 6538-9. PMID 12047166 DOI: 10.1021/ja020482+  0.96
2002 Prakash GKS, Mandal M, Schweizer S, Petasis NA, Olah GA. Stereoselective synthesis of anti-α-(difluoromethyl)-β-amino alcohols by boronic acid based three-component condensation. Stereoselective preparation of (2S,3R)-difluorothreonine Journal of Organic Chemistry. 67: 3718-3723. PMID 12027685 DOI: 10.1021/jo011116w  0.96
2001 Prakash GKS, Mandal M, Olah GA. Stereoselective Nucleophilic Trifluoromethylation of N-(tert-Butylsulfinyl)imines by Using Trimethyl(trifluoromethyl)silane. Angewandte Chemie (International Ed. in English). 40: 589-590. PMID 29712018 DOI: 10.1002/1521-3773(20010202)40:3<589::AID-ANIE589>3.0.CO;2-9  0.96
2001 Prakash GKS, Mandal M, Olah GA. Asymmetric synthesis of trifluoromethylated allylic amines using α,β-unsaturated N-tert-butanesulfinimines Organic Letters. 3: 2847-2850. PMID 11529772 DOI: 10.1021/ol010134x  0.96
2001 Prakash GK, Mandal M, Olah GA. Stereoselective Nucleophilic Trifluoromethylation of N-(tert-Butylsulfinyl)imines by Using Trimethyl(trifluoromethyl)silane Support of our work by Loker Hydrocarbon Research Institute is gratefully acknowledged. Angewandte Chemie (International Ed. in English). 40: 589-590. PMID 11180380 DOI: 10.1002/1521-3773(20010202)40:3<589::AID-ANIE589>3.0.CO;2-9  0.96
2001 Prakash GKS, Mandal M. Nucleophilic trifluoromethylation tamed Journal of Fluorine Chemistry. 112: 123-131. DOI: 10.1016/S0022-1139(01)00477-8  0.96
2001 Prakash GKS, Mandal M, Olah GA. Nucleophilic trifluoromethylation of N-tosyl aldimines Synlett. 77-78.  0.96
2000 Prakash GKS, Mandal M, Schweizer S, Petasis NA, Olah GA. A facile stereocontrolled synthesis of anti-α-(trifluoromethyl)-β-amino alcohols Organic Letters. 2: 3173-3176. PMID 11009374  0.96
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