David E. Kozono, Ph.D. - Publications

Affiliations: 
2005 Johns Hopkins University, Baltimore, MD 
Area:
water channels, aquaporins, aquaglyceroporins, malaria

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cai MY, Dunn CE, Chen W, Kochupurakkal BS, Nguyen H, Moreau LA, Shapiro GI, Parmar K, Kozono D, D'Andrea AD. Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection. Cell Reports. 30: 2402-2415.e5. PMID 32075772 DOI: 10.1016/J.Celrep.2020.01.052  0.317
2020 Kamran SC, Coroller T, Milani N, Agrawal V, Baldini EH, Chen AB, Johnson BE, Kozono D, Franco I, Chopra N, Zeleznik R, Aerts HJWL, Mak R. The impact of quantitative CT-based tumor volumetric features on the outcomes of patients with limited stage small cell lung cancer. Radiation Oncology (London, England). 15: 14. PMID 31937336 DOI: 10.1186/S13014-020-1460-4  0.325
2020 Ross HJ, Hu C, Higgins KA, Jabbour SK, Kozono DE, Owonikoko TK, Movsas B, Solberg T, Xiao C, Williams TM, Welsh JW, Simko J, Wang XF, Mohindra NA, Hsu C, et al. NRG Oncology/Alliance LU005: A phase II/III randomized clinical trial of chemoradiation versus chemoradiation plus atezolizumab in limited stage small cell lung cancer. Journal of Clinical Oncology. 38: TPS9082-TPS9082. DOI: 10.1200/Jco.2020.38.15_Suppl.Tps9082  0.339
2020 Sands J, Mandrekar SJ, Oxnard GR, Kozono DE, Hillman SL, Dahlberg SE, Sun Z, Chaft JE, Govindan R, Gerber DE, Gray JE, Malik SM, Mooney MM, Janne PA, Vokes EE, et al. ALCHEMIST: Adjuvant targeted therapy or immunotherapy for high-risk resected NSCLC. Journal of Clinical Oncology. 38: TPS9077-TPS9077. DOI: 10.1200/Jco.2020.38.15_Suppl.Tps9077  0.307
2020 Ross HJ, Kozono DE, Urbanic JJ, Williams TM, Dufrane C, Bara I, Gandhi M, Schulze K, Brockman JM, Wang XF, Gao J, Vokes EE, Stinchcombe T. AFT-16: Phase II trial of atezolizumab before and after definitive chemoradiation (CRT) for unresectable stage III non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 38: 9045-9045. DOI: 10.1200/Jco.2020.38.15_Suppl.9045  0.31
2019 Mitra D, Chen YH, Li R, Hermann G, Atkins K, Kozono D, Baldini EH, Aizer A, Chukwueke U, Mak RH. EGFR mutant locally advanced non-small cell lung cancer is at increased risk of brain metastasis. Clinical and Translational Radiation Oncology. 18: 32-38. PMID 31341973 DOI: 10.1016/J.Ctro.2019.06.008  0.305
2019 Atkins KM, Rawal B, Chaunzwa TL, Lamba N, Bitterman DS, Williams CL, Kozono DE, Baldini EH, Chen AB, Nguyen PL, D'Amico AV, Nohria A, Hoffmann U, Aerts HJWL, Mak RH. Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients With Lung Cancer. Journal of the American College of Cardiology. 73: 2976-2987. PMID 31196455 DOI: 10.1016/J.Jacc.2019.03.500  0.3
2018 Deraska PV, O'Leary C, Reavis HD, Labe S, Dinh TK, Lazaro JB, Sweeney C, D'Andrea AD, Kozono D. NF-κB inhibition by dimethylaminoparthenolide radiosensitizes non-small-cell lung carcinoma by blocking DNA double-strand break repair. Cell Death Discovery. 4: 10. PMID 29531807 DOI: 10.1038/S41420-017-0008-3  0.324
2018 Mitra D, Agarwal V, Chen Y, Baldini EH, Barbie DA, Chen AB, Glass B, Herman G, Kozono DE, Schoenfeld JD, Mak RH. The prognostic significance of PDL1 expression in locally advanced non-small-cell lung cancer (LA-NSCLC) treated with definitive intent. Journal of Clinical Oncology. 36: 150-150. DOI: 10.1200/Jco.2018.36.5_Suppl.150  0.319
2018 Deraska P, Reavis H, Labe S, D'Andrea A, Kozono D. Abstract 4287: Whole-genome CRISPR/Cas9 screen of the CHK1 inhibitor prexasertib implicates FAM122A loss as a potential resistance mechanism Cancer Research. 78: 4287-4287. DOI: 10.1158/1538-7445.Am2018-4287  0.316
2018 Chipidza FE, Franco I, Chen YH, Baldini EH, Chen AB, Kozono DE, Mak RH. Comorbidity is a Prognostic Factor in Early Stage Non-Small Cell Lung Cancer Patients Treated with Stereotactic Body Radiation Therapy International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.1829  0.334
2018 Bitterman DS, Rawal B, Atkins KM, Chaunzwa TL, Diao K, Catalano PS, Baldini EH, Chen AB, Kozono DE, Mak RH. Predictors of Radiation Esophagitis in Locally Advanced Non-Small Cell Lung Cancer with Modern Radiation Therapy Planning International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.07.1821  0.321
2018 Atkins KM, Rawal B, Williams CL, Bitterman DS, Chaunzwa TL, Verma V, Kozono DE, Baldini EH, Chen AB, Nohria A, Aerts H, Mak RH. Cardiac Events after Radiation Therapy (RT) for Stage II-III Non-Small Cell Lung Cancer (NSCLC): Analysis of 748 Patients International Journal of Radiation Oncology Biology Physics. 102. DOI: 10.1016/J.Ijrobp.2018.06.236  0.331
2017 Franco I, Chen YH, Chipidza F, Agrawal V, Romano J, Baldini E, Chen A, Colson Y, Hou Y, Kozono D, Wee J, Mak R. Use of frailty to predict survival in elderly patients with early stage non-small-cell lung cancer treated with stereotactic body radiation therapy. Journal of Geriatric Oncology. PMID 28941581 DOI: 10.1016/J.Jgo.2017.09.002  0.341
2017 Kozono DE, Salama JK, Stinchcombe T, Bogart J, Petty WJ, Guarino MJ, Bazhenova L, Larner JM, Weiss J, DiPetrillo TA, Feigenberg SJ, Xu T, Hu B, Nuthalapati S, Rosenwinkel L, et al. Tolerability of veliparib (V) in combination with carboplatin (C)/paclitaxel (P): Based chemoradiotherapy (CRT) in subjects with stage III non-small cell lung cancer (NSCLC). Journal of Clinical Oncology. 35: 8546-8546. DOI: 10.1200/Jco.2017.35.15_Suppl.8546  0.332
2017 Deraska PV, Reavis HD, Labe S, D'Andrea AD, Kozono D. Abstract 4189: Homologous recombination pathway-based biomarkers for treatment of non-small cell lung cancer with PARP inhibitors Cancer Research. 77: 4189-4189. DOI: 10.1158/1538-7445.Am2017-4189  0.357
2016 Agrawal V, Coroller TP, Hou Y, Lee SW, Romano JL, Baldini EH, Chen AB, Jackman DM, Kozono D, Swanson SJ, Wee JO, Aerts HJ, Mak RH. Radiologic-pathologic correlation of response to chemoradiation in resectable locally advanced NSCLC. Lung Cancer (Amsterdam, Netherlands). 102: 1-8. PMID 27987576 DOI: 10.1016/J.Lungcan.2016.10.002  0.312
2016 Hou Y, Hermann G, Lewis JH, Aerts HJ, Baldini EH, Chen AB, Colson YL, Hacker FL, Killoran JH, Kozono DE, Wagar M, Wee JO, Mak RH. Clinical Outcomes After Lung Stereotactic Body Radiation Therapy in Patients With or Without a Prior Lung Resection. American Journal of Clinical Oncology. PMID 27819875 DOI: 10.1097/Coc.0000000000000344  0.319
2016 Hou Y, Lee S, Agrawal V, Romano J, Baldini EH, Chen AB, Kozono DE, Killoran JH, Wagar M, Hacker FL, Aerts HJ, Lewis JH, Mak RH. Inter-scan and inter-observer tumour volume delineation variability on cone beam computed tomography in patients treated with stereotactic body radiation therapy for early-stage non-small cell lung cancer. Journal of Medical Imaging and Radiation Oncology. PMID 27709803 DOI: 10.1111/1754-9485.12537  0.329
2016 Mak RH, Hermann G, Aerts H, Chen AB, Baldini EH, Kozono DE, Chen YH, Catalano PJ, Janne P. Outcomes by EGFR, KRAS and ALK Genotype After Combined Modality Therapy for Locally Advanced Non-Small Cell Lung Cancer. International Journal of Radiation Oncology, Biology, Physics. 96: S156. PMID 27675664 DOI: 10.1016/J.Ijrobp.2016.06.378  0.317
2016 Yang D, O'Leary C, Deraska PV, D'Andrea AD, Haas-Kogan DA, Kozono DE. Exploiting Homologous Recombination Defects in N on-Small Cell Lung Cancer Through Combined PARP and Wee1 Inhibition. International Journal of Radiation Oncology, Biology, Physics. 96: E581-E582. PMID 27675075 DOI: 10.1016/J.Ijrobp.2016.06.2084  0.309
2016 Franco I, Romano J, Chipidza F, Baldini EH, Chen AB, Chen YH, Colson Y, Hou Y, Kozono DE, Wee J, Mak RH. Modified Frailty Index as a Predictor of Overall and Other Cause-Specific Survival in Early-Stage Non-Small Cell Lung Cancer Patients Treated With Stereotactic Body Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics. 96: E449-E450. PMID 27674720 DOI: 10.1016/J.Ijrobp.2016.06.1760  0.34
2016 Li R, Hermann G, Baldini E, Chen A, Jackman D, Kozono D, Nguyen P, Nohria A, Powell G, Mak R. Advanced nodal stage predicts venous thromboembolism in patients with locally advanced non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 96: 41-7. PMID 27133748 DOI: 10.1016/J.Lungcan.2016.03.004  0.343
2016 Deraska PV, O’Leary C, Lazaro J, Sweeney CJ, D’Andrea AD, Kozono D. Abstract 1644: NF-κB inhibitor DMAPT blocks non-homologous end-joining repair of radiation-induced DSBs in NSCLC Cancer Research. 76: 1644-1644. DOI: 10.1158/1538-7445.Am2016-1644  0.328
2015 Kushwaha D, O'Leary C, Cron KR, Deraska P, Zhu K, D'Andrea AD, Kozono D. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biology & Therapy. 16: 392-401. PMID 25692226 DOI: 10.1080/15384047.2014.1002358  0.345
2015 Mak RH, Hermann G, Lewis JH, Aerts HJ, Baldini EH, Chen AB, Colson YL, Hacker FH, Kozono D, Wee JO, Chen YH, Catalano PJ, Wong KK, Sher DJ. Outcomes by tumor histology and KRAS mutation status after lung stereotactic body radiation therapy for early-stage non-small-cell lung cancer. Clinical Lung Cancer. 16: 24-32. PMID 25450872 DOI: 10.1016/J.Cllc.2014.09.005  0.324
2015 Chen C, Kozono D, Li J, Nitta M, Sampetrean O, Ng K, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, et al. Abstract PR02: Dynamic epigenetic regulation of glioblastoma tumorigenicity through a LSD1-MYC-OLIG2 axis Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-Pr02  0.306
2015 Li J, Kozono D, Nitta M, Sampetrean O, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon C, et al. Abstract 979: Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression Cancer Research. 75: 979-979. DOI: 10.1158/1538-7445.Am2015-979  0.312
2015 Kozono D, Li J, Sampetrean O, Gonda D, Kushwaha D, Merzon D, Nitta M, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon C, et al. EPIG-02DYNAMIC EPIGENETIC MODULATION OF GLIOBLASTOMA TUMORIGENICITY BY INHIBITION OF LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) Neuro-Oncology. 17: v86.2-v86. DOI: 10.1093/Neuonc/Nov214.02  0.305
2014 Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Mike Makrigiorgos G, Kimmelman AC, Wong KK. Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nature Communications. 5: 5870. PMID 25519892 DOI: 10.1038/Ncomms6870  0.302
2014 Gray PJ, Mak RH, Yeap BY, Cryer SK, Pinnell NE, Christianson LW, Sher DJ, Arvold ND, Baldini EH, Chen AB, Kozono DE, Swanson SJ, Jackman DM, Alexander BM. Aggressive therapy for patients with non-small cell lung carcinoma and synchronous brain-only oligometastatic disease is associated with long-term survival Lung Cancer. 85: 239-244. PMID 24974152 DOI: 10.1016/J.Lungcan.2014.06.001  0.305
2014 Parikh RB, Cronin AM, Kozono DE, Oxnard GR, Mak RH, Jackman DM, Lo PC, Baldini EH, Johnson BE, Chen AB. Definitive primary therapy in patients presenting with oligometastatic non-small cell lung cancer. International Journal of Radiation Oncology, Biology, Physics. 89: 880-7. PMID 24867533 DOI: 10.1016/J.Ijrobp.2014.04.007  0.321
2014 Gazula A, Baldini EH, Chen A, Kozono D. Comparison of once and twice daily radiotherapy for limited stage small-cell lung cancer. Lung. 192: 151-158. PMID 24162870 DOI: 10.1007/S00408-013-9518-9  0.322
2013 Cron KR, Zhu K, Kushwaha DS, Hsieh G, Merzon D, Rameseder J, Chen CC, D'Andrea AD, Kozono D. Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. Plos One. 8: e73710. PMID 24040035 DOI: 10.1371/Journal.Pone.0073710  0.358
2013 Li J, Zhu S, Kozono D, Futulan D, Gonda D, Kushwaha D, Kahle K, Elledge S, Chen CC. Abstract 4366: ShRNA-based cellular proliferation signaling analysis revealed DRD2 as a novel therapeutic target for glioblastoma. Cancer Research. 73: 4366-4366. DOI: 10.1158/1538-7445.Am2013-4366  0.313
2013 Cron KR, Zhu K, Kushwaha D, Hsieh G, Merzon D, Monahan J, Chen CC, D'Andrea A, Kozono D. Abstract 1583: Proteasome inhibition as a strategy for non-small cell lung carcinoma via inhibition of DNA double strand break repair. Cancer Research. 73: 1583-1583. DOI: 10.1158/1538-7445.Am2013-1583  0.354
2013 Mak RH, Hermann G, Lewis JH, Baldini EH, Chen AB, Colson YL, Hacker FH, Kozono D, Wee JO, Sher DJ. Outcomes After Lung Stereotactic Body Radiation Therapy in Patients With K-ras-Mutant Non-Small Cell Lung Cancer International Journal of Radiation Oncology Biology Physics. 87. DOI: 10.1016/J.Ijrobp.2013.06.1337  0.33
2013 Kozono DE, Cron K, Kushwaha D, D'Andrea AD. Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer International Journal of Radiation Oncology Biology Physics. 87. DOI: 10.1016/J.Ijrobp.2013.06.060  0.319
2012 Zhu K, Kushwaha D, Cron K, Hsieh G, Merzon D, Evans D, Ng K, Chen CC, D'Andrea AD, Kozono D. Abstract 1448: Whole genome RNAi screen identifies proteasome inhibition as a strategy for NSCLC radiosensitization Cancer Research. 72: 1448-1448. DOI: 10.1158/1538-7445.Am2012-1448  0.361
2010 Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, et al. Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. Plos One. 5: e10767. PMID 20532243 DOI: 10.1371/Journal.Pone.0010767  0.305
2010 Kozono D, Ng K, Hsieh G, Merzon D, Nitta M, Zinn PO, Kahle K, Elledge S, D'Andrea A, Chen CC. Abstract 1318: Proteasome and Fanconi Anemia/BRCA pathways as prognostic determinants of glioblastoma response to radiation and temozolomide: a proposed clinical trial Cancer Research. 70: 1318-1318. DOI: 10.1158/1538-7445.Am10-1318  0.337
2006 Palanivelu DV, Kozono DE, Engel A, Suda K, Lustig A, Agre P, Schirmer T. Co-axial association of recombinant eye lens aquaporin-0 observed in loosely packed 3D crystals. Journal of Molecular Biology. 355: 605-11. PMID 16309700 DOI: 10.1016/J.Jmb.2005.10.032  0.497
2005 Lee JK, Kozono D, Remis J, Kitagawa Y, Agre P, Stroud RM. Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A. Proceedings of the National Academy of Sciences of the United States of America. 102: 18932-7. PMID 16361443 DOI: 10.1073/Pnas.0509469102  0.539
2005 Liu K, Kozono D, Kato Y, Agre P, Hazama A, Yasui M. Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution. Proceedings of the National Academy of Sciences of the United States of America. 102: 2192-7. PMID 15671159 DOI: 10.1073/Pnas.0409232102  0.549
2004 King LS, Kozono D, Agre P. From structure to disease: the evolving tale of aquaporin biology. Nature Reviews. Molecular Cell Biology. 5: 687-98. PMID 15340377 DOI: 10.1038/Nrm1469  0.547
2004 Agre P, Kozono D. Aquaporin water channels: molecular mechanisms for human diseases. Febs Letters. 555: 72-8. PMID 14630322 DOI: 10.1016/S0014-5793(03)01083-4  0.558
2004 Palanivelu D, Agre P, Kozono D, Lustig A, Suda K, Schirmer T. Co-axial association of eye lens aquaporin AQP0 Acta Crystallographica Section a Foundations of Crystallography. 60: s130-s130. DOI: 10.1107/S0108767304097430  0.41
2003 Carbrey JM, Gorelick-Feldman DA, Kozono D, Praetorius J, Nielsen S, Agre P. Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver. Proceedings of the National Academy of Sciences of the United States of America. 100: 2945-50. PMID 12594337 DOI: 10.1073/Pnas.0437994100  0.71
2003 Kozono D, Ding X, Iwasaki I, Meng X, Kamagata Y, Agre P, Kitagawa Y. Functional expression and characterization of an archaeal aquaporin. AqpM from methanothermobacter marburgensis. The Journal of Biological Chemistry. 278: 10649-56. PMID 12519768 DOI: 10.1074/Jbc.M212418200  0.544
2002 Ikeda M, Beitz E, Kozono D, Guggino WB, Agre P, Yasui M. Characterization of aquaporin-6 as a nitrate channel in mammalian cells. Requirement of pore-lining residue threonine 63. The Journal of Biological Chemistry. 277: 39873-9. PMID 12177001 DOI: 10.1074/Jbc.M207008200  0.555
2002 Kozono D, Yasui M, King LS, Agre P. Aquaporin water channels: atomic structure molecular dynamics meet clinical medicine. The Journal of Clinical Investigation. 109: 1395-9. PMID 12045251 DOI: 10.1172/JCI15851  0.484
2002 Hazama A, Kozono D, Guggino WB, Agre P, Yasui M. Ion permeation of AQP6 water channel protein. Single channel recordings after Hg2+ activation. The Journal of Biological Chemistry. 277: 29224-30. PMID 12034750 DOI: 10.1074/Jbc.M204258200  0.538
2002 Kozono D, Yasui M, King LS, Agre P. Aquaporin water channels: atomic structure molecular dynamics meet clinical medicine Journal of Clinical Investigation. 109: 1395-1399. DOI: 10.1172/Jci0215851  0.554
2001 Saparov SM, Kozono D, Rothe U, Agre P, Pohl P. Water and ion permeation of aquaporin-1 in planar lipid bilayers. Major differences in structural determinants and stoichiometry. The Journal of Biological Chemistry. 276: 31515-20. PMID 11410596 DOI: 10.1074/Jbc.M104267200  0.55
2001 Agre PC, Borgnia MJ, Yasui M, Neely JD, Carbrey J, Kozono D, Beitz E, Hoffert J, Leitch V, King LS. Chapter 1 discovery of the aquaporins and their impact on basic and clinical physiology Current Topics in Membranes. 51: 1-38. DOI: 10.1016/S1063-5823(01)51003-0  0.699
1999 Borgnia MJ, Kozono D, Calamita G, Maloney PC, Agre P. Functional reconstitution and characterization of AqpZ, the E. coli water channel protein. Journal of Molecular Biology. 291: 1169-79. PMID 10518952 DOI: 10.1006/Jmbi.1999.3032  0.542
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