Year |
Citation |
Score |
2018 |
Li M, Wu Y, Zou B, Wang X, Li M, Yu H. Identification of WB4101, an alpha1-adrenoceptor antagonist, as a sodium channel blocker. Molecular Pharmacology. PMID 29884692 DOI: 10.1124/mol.117.111252 |
0.329 |
|
2017 |
Wu Y, Zou B, Liang L, Li M, Tao YX, Yu H, Wang X, Li M. Loperamide inhibits sodium channels to alleviate inflammatory hyperalgesia. Neuropharmacology. PMID 28216001 DOI: 10.1016/J.Neuropharm.2017.02.010 |
0.384 |
|
2016 |
Yu HB, Zou BY, Wang XL, Li M. Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay. Acta Pharmacologica Sinica. 37: 111-23. PMID 26725739 DOI: 10.1038/aps.2015.143 |
0.301 |
|
2015 |
Zou B. Ion channel profiling to advance drug discovery and development. Drug Discovery Today. Technologies. 18: 18-23. PMID 26723888 DOI: 10.1016/J.Ddtec.2015.10.003 |
0.386 |
|
2015 |
Yu H, Zou B, Wang X, Li M. Effect of tyrphostin AG879 on Kv 4.2 and Kv 4.3 potassium channels. British Journal of Pharmacology. 172: 3370-82. PMID 25752739 DOI: 10.1111/Bph.13127 |
0.41 |
|
2015 |
Du F, Babcock JJ, Yu H, Zou B, Li M. Global analysis reveals families of chemical motifs enriched for HERG inhibitors. Plos One. 10: e0118324. PMID 25700001 DOI: 10.1371/Journal.Pone.0118324 |
0.367 |
|
2015 |
Zhang H, Zou B, Du F, Xu K, Li M. Reporting sodium channel activity using calcium flux: pharmacological promiscuity of cardiac Nav1.5. Molecular Pharmacology. 87: 207-17. PMID 25422141 DOI: 10.1124/Mol.114.094789 |
0.438 |
|
2014 |
Flaherty DP, Simpson DS, Miller M, Maki BE, Zou B, Shi J, Wu M, McManus OB, Aubé J, Li M, Golden JE. Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold. Bioorganic & Medicinal Chemistry Letters. 24: 3968-73. PMID 25017033 DOI: 10.1016/J.Bmcl.2014.06.032 |
0.315 |
|
2014 |
Bruner JK, Zou B, Zhang H, Zhang Y, Schmidt K, Li M. Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel. European Journal of Pharmacology. 740: 603-10. PMID 24972239 DOI: 10.1016/J.Ejphar.2014.06.021 |
0.435 |
|
2013 |
Yu H, Lin Z, Mattmann ME, Zou B, Terrenoire C, Zhang H, Wu M, McManus OB, Kass RS, Lindsley CW, Hopkins CR, Li M. Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 8732-7. PMID 23650380 DOI: 10.1073/Pnas.1300684110 |
0.406 |
|
2012 |
Potet F, Lorinc AN, Chaigne S, Hopkins CR, Venkataraman R, Stepanovic SZ, Lewis LM, Days E, Sidorov VY, Engers DW, Zou B, Afshartous D, George AL, Campbell CM, Balser JR, et al. Identification and characterization of a compound that protects cardiac tissue from human Ether-Ã -go-go-related gene (hERG)-related drug-induced arrhythmias. The Journal of Biological Chemistry. 287: 39613-25. PMID 23033485 DOI: 10.1074/Jbc.M112.380162 |
0.367 |
|
2012 |
Cheung YY, Yu H, Xu K, Zou B, Wu M, McManus OB, Li M, Lindsley CW, Hopkins CR. Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent, brain penetrant K(v)7.2 channel inhibitor. Journal of Medicinal Chemistry. 55: 6975-9. PMID 22793372 DOI: 10.1021/Jm300700V |
0.399 |
|
2012 |
Zhang H, Zou B, Yu H, Moretti A, Wang X, Yan W, Babcock JJ, Bellin M, McManus OB, Tomaselli G, Nan F, Laugwitz KL, Li M. Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 109: 11866-71. PMID 22745159 DOI: 10.1073/Pnas.1205266109 |
0.362 |
|
2011 |
Du F, Yu H, Zou B, Babcock J, Long S, Li M. hERGCentral: a large database to store, retrieve, and analyze compound-human Ether-à-go-go related gene channel interactions to facilitate cardiotoxicity assessment in drug development. Assay and Drug Development Technologies. 9: 580-8. PMID 22149888 DOI: 10.1089/Adt.2011.0425 |
0.38 |
|
2011 |
Yu H, Wu M, Townsend SD, Zou B, Long S, Daniels JS, McManus OB, Li M, Lindsley CW, Hopkins CR. Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. Acs Chemical Neuroscience. 2: 572-577. PMID 22125664 DOI: 10.1021/Cn200065B |
0.42 |
|
2010 |
Zou B, Yu H, Babcock JJ, Chanda P, Bader JS, McManus OB, Li M. Profiling diverse compounds by flux- and electrophysiology-based primary screens for inhibition of human Ether-à-go-go related gene potassium channels. Assay and Drug Development Technologies. 8: 743-54. PMID 21158688 DOI: 10.1089/Adt.2010.0339 |
0.386 |
|
2004 |
Kawasaki F, Zou B, Xu X, Ordway RW. Active zone localization of presynaptic calcium channels encoded by the cacophony locus of Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 282-5. PMID 14715960 DOI: 10.1523/Jneurosci.3553-03.2004 |
0.342 |
|
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