John A. T. Young - Publications

Affiliations: 
2003- immunology and microbial pathogenesis program Salk Institute for Biological Studies, La Jolla, CA, United States 
Website:
http://www.salk.edu/insidesalk/articlenin.php?id=209

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Rodgers MJ, Banks DJ, Bradley KA, Young JA. CHD1 and CHD2 are positive regulators of HIV-1 gene expression. Virology Journal. 11: 180. PMID 25297984 DOI: 10.1186/1743-422X-11-180  0.534
2013 Bhattacharyya S, Zagórska A, Lew ED, Shrestha B, Rothlin CV, Naughton J, Diamond MS, Lemke G, Young JA. Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors. Cell Host & Microbe. 14: 136-47. PMID 23954153 DOI: 10.1016/J.Chom.2013.07.005  0.406
2013 Seidel S, Bruce J, Leblanc M, Lee KF, Fan H, Ahlquist P, Young JA. ZASC1 knockout mice exhibit an early bone marrow-specific defect in murine leukemia virus replication. Virology Journal. 10: 130. PMID 23617998 DOI: 10.1186/1743-422X-10-130  0.767
2012 Thomas D, Naughton J, Cote C, Welkos S, Manchester M, Young JA. Delayed toxicity associated with soluble anthrax toxin receptor decoy-Ig fusion protein treatment. Plos One. 7: e34611. PMID 22511955 DOI: 10.1371/Journal.Pone.0034611  0.456
2011 Pilpa RM, Bayrhuber M, Marlett JM, Riek R, Young JA. A receptor-based switch that regulates anthrax toxin pore formation. Plos Pathogens. 7: e1002354. PMID 22174672 DOI: 10.1371/Journal.Ppat.1002354  0.415
2011 Jha NK, Latinovic O, Martin E, Novitskiy G, Marin M, Miyauchi K, Naughton J, Young JA, Melikyan GB. Imaging single retrovirus entry through alternative receptor isoforms and intermediates of virus-endosome fusion. Plos Pathogens. 7: e1001260. PMID 21283788 DOI: 10.1371/journal.ppat.1001260  0.447
2010 Choi J, Young JA, Callaway EM. Selective viral vector transduction of ErbB4 expressing cortical interneurons in vivo with a viral receptor-ligand bridge protein. Proceedings of the National Academy of Sciences of the United States of America. 107: 16703-8. PMID 20823240 DOI: 10.1073/Pnas.1006233107  0.505
2010 König R, Stertz S, Zhou Y, Inoue A, Hoffmann HH, Bhattacharyya S, Alamares JG, Tscherne DM, Ortigoza MB, Liang Y, Gao Q, Andrews SE, Bandyopadhyay S, De Jesus P, Tu BP, ... ... Young JA, et al. Human host factors required for influenza virus replication. Nature. 463: 813-7. PMID 20027183 DOI: 10.1038/Nature08699  0.333
2009 van der Goot G, Young JA. Receptors of anthrax toxin and cell entry. Molecular Aspects of Medicine. 30: 406-12. PMID 19732789 DOI: 10.1016/j.mam.2009.08.007  0.414
2008 König R, Zhou Y, Elleder D, Diamond TL, Bonamy GM, Irelan JT, Chiang CY, Tu BP, De Jesus PD, Lilley CE, Seidel S, Opaluch AM, Caldwell JS, Weitzman MD, Kuhen KL, ... ... Young JA, et al. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. Cell. 135: 49-60. PMID 18854154 DOI: 10.1016/J.Cell.2008.07.032  0.761
2008 Ryan PL, Young JA. Evidence against a human cell-specific role for LRP6 in anthrax toxin entry. Plos One. 3: e1817. PMID 18350154 DOI: 10.1371/Journal.Pone.0001817  0.592
2007 Manayani DJ, Thomas D, Dryden KA, Reddy V, Siladi ME, Marlett JM, Rainey GJ, Pique ME, Scobie HM, Yeager M, Young JA, Manchester M, Schneemann A. A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. Plos Pathogens. 3: 1422-31. PMID 17922572 DOI: 10.1371/Journal.Ppat.0030142  0.723
2007 Scobie HM, Marlett JM, Rainey GJ, Lacy DB, Collier RJ, Young JA. Anthrax toxin receptor 2 determinants that dictate the pH threshold of toxin pore formation. Plos One. 2: e329. PMID 17389920 DOI: 10.1371/Journal.Pone.0000329  0.66
2007 Young JA, Collier RJ. Anthrax toxin: receptor binding, internalization, pore formation, and translocation. Annual Review of Biochemistry. 76: 243-65. PMID 17335404 DOI: 10.1146/annurev.biochem.75.103004.142728  0.416
2007 Babel AR, Bruce J, Young JA. The hr1 and fusion peptide regions of the subgroup B avian sarcoma and leukosis virus envelope glycoprotein influence low pH-dependent membrane fusion. Plos One. 2: e171. PMID 17245447 DOI: 10.1371/journal.pone.0000171  0.726
2006 Scobie HM, Young JA. Divalent metal ion coordination by residue T118 of anthrax toxin receptor 2 is not essential for protective antigen binding. Plos One. 1: e99. PMID 17183731 DOI: 10.1371/journal.pone.0000099  0.683
2006 Scobie HM, Wigelsworth DJ, Marlett JM, Thomas D, Rainey GJ, Lacy DB, Manchester M, Collier RJ, Young JA. Anthrax toxin receptor 2-dependent lethal toxin killing in vivo. Plos Pathogens. 2: e111. PMID 17054395 DOI: 10.1371/Journal.Ppat.0020111  0.683
2006 Barnard RJ, Elleder D, Young JA. Avian sarcoma and leukosis virus-receptor interactions: from classical genetics to novel insights into virus-cell membrane fusion. Virology. 344: 25-9. PMID 16364732 DOI: 10.1016/j.virol.2005.09.021  0.496
2005 Bruce JW, Bradley KA, Ahlquist P, Young JA. Isolation of cell lines that show novel, murine leukemia virus-specific blocks to early steps of retroviral replication. Journal of Virology. 79: 12969-78. PMID 16188999 DOI: 10.1128/Jvi.79.20.12969-12978.2005  0.597
2005 Wolfe JT, Krantz BA, Rainey GJ, Young JA, Collier RJ. Whole-cell voltage clamp measurements of anthrax toxin pore current. The Journal of Biological Chemistry. 280: 39417-22. PMID 16183642 DOI: 10.1074/jbc.M509049200  0.327
2005 Rainey GJ, Wigelsworth DJ, Ryan PL, Scobie HM, Collier RJ, Young JA. Receptor-specific requirements for anthrax toxin delivery into cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 13278-83. PMID 16141341 DOI: 10.1073/Pnas.0505865102  0.791
2005 Scobie HM, Thomas D, Marlett JM, Destito G, Wigelsworth DJ, Collier RJ, Young JA, Manchester M. A soluble receptor decoy protects rats against anthrax lethal toxin challenge. The Journal of Infectious Diseases. 192: 1047-51. PMID 16107958 DOI: 10.1086/432731  0.706
2005 Klucking S, Collins AS, Young JA. Avian sarcoma and leukosis virus cytopathic effect in the absence of TVB death domain signaling. Journal of Virology. 79: 8243-8. PMID 15956570 DOI: 10.1128/Jvi.79.13.8243-8248.2005  0.815
2005 Melikyan GB, Barnard RJ, Abrahamyan LG, Mothes W, Young JA. Imaging individual retroviral fusion events: from hemifusion to pore formation and growth. Proceedings of the National Academy of Sciences of the United States of America. 102: 8728-33. PMID 15937118 DOI: 10.1073/Pnas.0501864102  0.484
2005 Scobie HM, Young JA. Interactions between anthrax toxin receptors and protective antigen. Current Opinion in Microbiology. 8: 106-12. PMID 15694864 DOI: 10.1016/j.mib.2004.12.005  0.724
2004 Barnard RJ, Narayan S, Dornadula G, Miller MD, Young JA. Low pH is required for avian sarcoma and leukosis virus Env-dependent viral penetration into the cytosol and not for viral uncoating. Journal of Virology. 78: 10433-41. PMID 15367609 DOI: 10.1128/Jvi.78.19.10433-10441.2004  0.653
2004 Lim KI, Narayan S, Young JA, Yin J. Effects of lipid rafts on dynamics of retroviral entry and trafficking: Quantitative analysis. Biotechnology and Bioengineering. 86: 650-60. PMID 15137076 DOI: 10.1002/Bit.20108  0.692
2004 Narayan S, Young JA. Reconstitution of retroviral fusion and uncoating in a cell-free system. Proceedings of the National Academy of Sciences of the United States of America. 101: 7721-6. PMID 15128947 DOI: 10.1073/Pnas.0401312101  0.612
2004 Lacy DB, Wigelsworth DJ, Scobie HM, Young JA, Collier RJ. Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor. Proceedings of the National Academy of Sciences of the United States of America. 101: 6367-72. PMID 15079089 DOI: 10.1073/Pnas.0401506101  0.72
2004 Melikyan GB, Barnard RJ, Markosyan RM, Young JA, Cohen FS. Low pH is required for avian sarcoma and leukosis virus Env-induced hemifusion and fusion pore formation but not for pore growth. Journal of Virology. 78: 3753-62. PMID 15016895 DOI: 10.1128/Jvi.78.7.3753-3762.2004  0.401
2004 Klucking S, Young JA. Amino acid residues Tyr-67, Asn-72, and Asp-73 of the TVB receptor are important for subgroup E avian sarcoma and leukosis virus interaction. Virology. 318: 371-80. PMID 14972562 DOI: 10.1016/J.Virol.2003.09.024  0.825
2003 Collier RJ, Young JA. Anthrax toxin. Annual Review of Cell and Developmental Biology. 19: 45-70. PMID 14570563 DOI: 10.1146/annurev.cellbio.19.111301.140655  0.356
2003 Bradley KA, Mogridge J, Jonah G, Rainey A, Batty S, Young JA. Binding of anthrax toxin to its receptor is similar to alpha integrin-ligand interactions. The Journal of Biological Chemistry. 278: 49342-7. PMID 14507921 DOI: 10.1074/Jbc.M307900200  0.67
2003 Barnard RJ, Young JA. Alpharetrovirus envelope-receptor interactions. Current Topics in Microbiology and Immunology. 281: 107-36. PMID 12932076 DOI: 10.1007/978-3-642-19012-4_3  0.366
2003 Yu X, Wang QY, Guo Y, Dolmer K, Young JA, Gettins PG, Rong L. Kinetic analysis of binding interaction between the subgroup A Rous sarcoma virus glycoprotein SU and its cognate receptor Tva: calcium is not required for ligand binding. Journal of Virology. 77: 7517-26. PMID 12805452 DOI: 10.1128/Jvi.77.13.7517-7526.2003  0.512
2003 Scobie HM, Rainey GJ, Bradley KA, Young JA. Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proceedings of the National Academy of Sciences of the United States of America. 100: 5170-4. PMID 12700348 DOI: 10.1073/Pnas.0431098100  0.801
2003 Bradley KA, Young JA. Anthrax toxin receptor proteins. Biochemical Pharmacology. 65: 309-14. PMID 12527323 DOI: 10.1016/S0006-2952(02)01455-7  0.667
2003 Narayan S, Barnard RJ, Young JA. Two retroviral entry pathways distinguished by lipid raft association of the viral receptor and differences in viral infectivity. Journal of Virology. 77: 1977-83. PMID 12525631 DOI: 10.1128/Jvi.77.3.1977-1983.2003  0.727
2002 Klucking S, Adkins HB, Young JA. Resistance to infection by subgroups B, D, and E avian sarcoma and leukosis viruses is explained by a premature stop codon within a resistance allele of the tvb receptor gene. Journal of Virology. 76: 7918-21. PMID 12097608 DOI: 10.1128/Jvi.76.15.7918-7921.2002  0.783
2002 Chi Y, Diaz-Griffero F, Wang C, Young JA, Brojatsch J. An NF-kappa B-dependent survival pathway protects against cell death induced by TVB receptors for avian leukosis viruses. Journal of Virology. 76: 5581-7. PMID 11991986 DOI: 10.1128/Jvi.76.11.5581-5587.2002  0.489
2002 Knauss DJ, Young JA. A fifteen-amino-acid TVB peptide serves as a minimal soluble receptor for subgroup B avian leukosis and sarcoma viruses. Journal of Virology. 76: 5404-10. PMID 11991969 DOI: 10.1128/Jvi.76.11.5404-5410.2002  0.823
2002 Snitkovsky S, Young JA. Targeting retroviral vector infection to cells that express heregulin receptors using a TVA-heregulin bridge protein. Virology. 292: 150-5. PMID 11878917 DOI: 10.1006/Viro.2001.1314  0.839
2001 Bradley KA, Mogridge J, Mourez M, Collier RJ, Young JA. Identification of the cellular receptor for anthrax toxin. Nature. 414: 225-9. PMID 11700562 DOI: 10.1038/N35101999  0.656
2001 Adkins HB, Blacklow SC, Young JA. Two functionally distinct forms of a retroviral receptor explain the nonreciprocal receptor interference among subgroups B, D, and E avian leukosis viruses. Journal of Virology. 75: 3520-6. PMID 11264341 DOI: 10.1128/Jvi.75.8.3520-3526.2001  0.839
2001 Snitkovsky S, Niederman TM, Mulligan RC, Young JA. Targeting avian leukosis virus subgroup A vectors by using a TVA-VEGF bridge protein. Journal of Virology. 75: 1571-5. PMID 11152532 DOI: 10.1128/Jvi.75.3.1571-1575.2001  0.832
2000 Mothes W, Boerger AL, Narayan S, Cunningham JM, Young JA. Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoprotein. Cell. 103: 679-89. PMID 11106737 DOI: 10.1016/S0092-8674(00)00170-7  0.792
2000 Brojatsch J, Naughton J, Adkins HB, Young JA. TVB receptors for cytopathic and noncytopathic subgroups of avian leukosis viruses are functional death receptors. Journal of Virology. 74: 11490-4. PMID 11090145 DOI: 10.1128/Jvi.74.24.11490-11494.2000  0.83
2000 Snitkovsky S, Niederman TM, Carter BS, Mulligan RC, Young JA. A TVA-single-chain antibody fusion protein mediates specific targeting of a subgroup A avian leukosis virus vector to cells expressing a tumor-specific form of epidermal growth factor receptor. Journal of Virology. 74: 9540-5. PMID 11000224 DOI: 10.1128/Jvi.74.20.9540-9545.2000  0.827
2000 Adkins HB, Brojatsch J, Young JA. Identification and characterization of a shared TNFR-related receptor for subgroup B, D, and E avian leukosis viruses reveal cysteine residues required specifically for subgroup E viral entry. Journal of Virology. 74: 3572-78. PMID 10729132 DOI: 10.1128/Jvi.74.8.3572-3578.2000  0.841
1999 Boerger AL, Snitkovsky S, Young JA. Retroviral vectors preloaded with a viral receptor-ligand bridge protein are targeted to specific cell types. Proceedings of the National Academy of Sciences of the United States of America. 96: 9867-72. PMID 10449786 DOI: 10.1073/Pnas.96.17.9867  0.791
1998 Snitkovsky S, Young JA. Cell-specific viral targeting mediated by a soluble retroviral receptor-ligand fusion protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 7063-8. PMID 9618539 DOI: 10.1073/Pnas.95.12.7063  0.833
1998 Bates P, Rong L, Varmus HE, Young JA, Crittenden LB. Genetic mapping of the cloned subgroup A avian sarcoma and leukosis virus receptor gene to the TVA locus. Journal of Virology. 72: 2505-8. PMID 9499114 DOI: 10.1128/Jvi.72.3.2505-2508.1998  0.7
1997 Hernandez LD, Peters RJ, Delos SE, Young JA, Agard DA, White JM. Activation of a retroviral membrane fusion protein: soluble receptor-induced liposome binding of the ALSV envelope glycoprotein. The Journal of Cell Biology. 139: 1455-64. PMID 9396751 DOI: 10.1083/Jcb.139.6.1455  0.501
1997 Adkins HB, Brojatsch J, Naughton J, Rolls MM, Pesola JM, Young JA. Identification of a cellular receptor for subgroup E avian leukosis virus. Proceedings of the National Academy of Sciences of the United States of America. 94: 11617-22. PMID 9326659 DOI: 10.1073/Pnas.94.21.11617  0.838
1995 Zingler K, Bélanger Ca, Peters R, Agard E, Young JA. Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor. Journal of Virology. 69: 4261-4266. DOI: 10.1128/Jvi.69.7.4261-4266.1995  0.464
1995 Bélanger C, Zingler K, Young JA. Importance of cysteines in the LDLR-related domain of the subgroup A avian leukosis and sarcoma virus receptor for viral entry. Journal of Virology. 69: 1019-1024. DOI: 10.1128/jvi.69.2.1019-1024.1995  0.431
1994 Federspiel MJ, Bates P, Young JA, Varmus HE, Hughes SH. A system for tissue-specific gene targeting: transgenic mice susceptible to subgroup A avian leukosis virus-based retroviral vectors. Proceedings of the National Academy of Sciences of the United States of America. 91: 11241-5. PMID 7972042 DOI: 10.1073/Pnas.91.23.11241  0.718
1994 Connolly L, Zingler K, Young JA. A soluble form of a receptor for subgroup A avian leukosis and sarcoma viruses (ALSV-A) blocks infection and binds directly to ALSV-A. Journal of Virology. 68: 2760-2764. DOI: 10.1128/jvi.68.4.2760-2764.1994  0.418
1993 Bates P, Young JA, Varmus HE. A receptor for subgroup A Rous sarcoma virus is related to the low density lipoprotein receptor. Cell. 74: 1043-51. PMID 8402880 DOI: 10.1016/0092-8674(93)90726-7  0.797
1993 Young JA, Bates P, Varmus HE. Isolation of a chicken gene that confers susceptibility to infection by subgroup A avian leukosis and sarcoma viruses. Journal of Virology. 67: 1811-6. PMID 8383211 DOI: 10.1128/Jvi.67.4.1811-1816.1993  0.709
1990 Young JA, Bates P, Willert K, Varmus HE. Efficient incorporation of human CD4 protein into avian leukosis virus particles. Science (New York, N.Y.). 250: 1421-3. PMID 2175047 DOI: 10.1126/Science.2175047  0.698
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