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Chris A. Kieslich, Ph.D. - Publications

Affiliations: 
2012 Bioengineering University of California, Riverside, Riverside, CA, United States 
Area:
Biomedical Engineering, General Biophysics, Bioinformatics Biology
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Narkhede YB, Gautam AK, Hsu RV, Rodriguez W, Zewde NT, Harrison RES, Arantes PR, Gaieb Z, Gorham RD, Kieslich C, Morikis D, Sahu A, Palermo G. Role of Electrostatic Hotspots in the Selectivity of Complement Control Proteins Toward Human and Bovine Complement Inhibition. Frontiers in Molecular Biosciences. 8: 618068. PMID 33829039 DOI: 10.3389/fmolb.2021.618068  0.766
2018 Onel M, Kieslich CA, Guzman YA, Floudas CA, Pistikopoulos EN. Big Data Approach to Batch Process Monitoring: Simultaneous Fault Detection and Diagnosis Using Nonlinear Support Vector Machine-based Feature Selection. Computers & Chemical Engineering. 115: 46-63. PMID 30386002 DOI: 10.1016/J.Compchemeng.2018.03.025  0.447
2018 Mohan RR, Wilson M, Gorham RD, Harrison RES, Morikis VA, Kieslich CA, Orr AA, Coley AV, Tamamis P, Morikis D. Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands. Acs Omega. 3: 6427-6438. PMID 30221234 DOI: 10.1021/acsomega.8b00606  0.775
2018 Keasar C, McGuffin LJ, Wallner B, Chopra G, Adhikari B, Bhattacharya D, Blake L, Bortot LO, Cao R, Dhanasekaran BK, Dimas I, Faccioli RA, Faraggi E, Ganzynkowicz R, Ghosh S, ... ... Kieslich C, et al. An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12. Scientific Reports. 8: 9939. PMID 29967418 DOI: 10.1038/s41598-018-26812-8  0.77
2018 Kieslich CA, Boukouvala F, Floudas CA. Optimization of black-box problems using Smolyak grids and polynomial approximations Journal of Global Optimization. 71: 845-869. DOI: 10.1007/S10898-018-0643-0  0.708
2017 Harrison RES, Mohan RR, Gorham RD, Kieslich CA, Morikis D. AESOP: A Python Library for Investigating Electrostatics in Protein Interactions. Biophysical Journal. 112: 1761-1766. PMID 28494947 DOI: 10.1016/J.Bpj.2017.04.005  0.795
2017 Khoury GA, Smadbeck J, Kieslich CA, Koskosidis AJ, Guzman YA, Tamamis P, Floudas CA. Princeton_TIGRESS 2.0: High refinement consistency and net gains through support vector machines and molecular dynamics in double-blind predictions during the CASP11 experiment. Proteins. PMID 28241391 DOI: 10.1002/Prot.25274  0.797
2016 Kieslich CA, Smadbeck J, Khoury GA, Floudas C. conSSert: Consensus SVM model for accurate prediction of ordered secondary structure. Journal of Chemical Information and Modeling. PMID 26928531 DOI: 10.1021/Acs.Jcim.5B00566  0.707
2016 Kieslich CA, Tamamis P, Guzman YA, Onel M, Floudas CA. Highly Accurate Structure-Based Prediction of HIV-1 Coreceptor Usage Suggests Intermolecular Interactions Driving Tropism. Plos One. 11: e0148974. PMID 26859389 DOI: 10.1371/Journal.Pone.0148974  0.711
2014 Halai R, Bellows-Peterson ML, Branchett W, Smadbeck J, Kieslich CA, Croker DE, Cooper MA, Morikis D, Woodruff TM, Floudas CA, Monk PN. Derivation of ligands for the complement C3a receptor from the C-terminus of C5a. European Journal of Pharmacology. 745: 176-81. PMID 25446428 DOI: 10.1016/J.Ejphar.2014.10.041  0.738
2014 Tamamis P, Kieslich CA, Nikiforovich GV, Woodruff TM, Morikis D, Archontis G. Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and docking. Bmc Biophysics. 7: 5. PMID 25170421 DOI: 10.1186/2046-1682-7-5  0.774
2014 Khoury GA, Smadbeck J, Tamamis P, Vandris AC, Kieslich CA, Floudas CA. Forcefield_NCAA: ab initio charge parameters to aid in the discovery and design of therapeutic proteins and peptides with unnatural amino acids and their application to complement inhibitors of the compstatin family. Acs Synthetic Biology. 3: 855-69. PMID 24932669 DOI: 10.1021/Sb400168U  0.797
2014 Liu Y, Kieslich CA, Morikis D, Liao J. Engineering pre-SUMO4 as efficient substrate of SENP2. Protein Engineering, Design & Selection : Peds. 27: 117-26. PMID 24671712 DOI: 10.1093/Protein/Gzu004  0.612
2014 Khoury GA, Smadbeck J, Kieslich CA, Floudas CA. Protein folding and de novo protein design for biotechnological applications. Trends in Biotechnology. 32: 99-109. PMID 24268901 DOI: 10.1016/J.Tibtech.2013.10.008  0.728
2014 Khoury GA, Tamamis P, Pinnaduwage N, Smadbeck J, Kieslich CA, Floudas CA. Princeton_TIGRESS: protein geometry refinement using simulations and support vector machines. Proteins. 82: 794-814. PMID 24174311 DOI: 10.1002/Prot.24459  0.786
2013 Khoury GA, Thompson JP, Smadbeck J, Kieslich CA, Floudas CA. Forcefield_PTM: Ab Initio Charge and AMBER Forcefield Parameters for Frequently Occurring Post-Translational Modifications. Journal of Chemical Theory and Computation. 9: 5653-5674. PMID 24489522 DOI: 10.1021/Ct400556V  0.728
2013 Gorham RD, Forest DL, Tamamis P, López de Victoria A, Kraszni M, Kieslich CA, Banna CD, Bellows-Peterson ML, Larive CK, Floudas CA, Archontis G, Johnson LV, Morikis D. Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures. Experimental Eye Research. 116: 96-108. PMID 23954241 DOI: 10.1016/J.Exer.2013.07.023  0.765
2013 Kieslich CA, Shin D, López de Victoria A, González-Rivera G, Morikis D. A predictive model for HIV type 1 coreceptor selectivity. Aids Research and Human Retroviruses. 29: 1386-94. PMID 23808984 DOI: 10.1089/Aid.2012.0173  0.593
2013 El-Assaad AM, Kieslich CA, Gorham RD, Morikis D. Erratum to “Electrostatic exploration of the C3d–FH4 interaction using a computational alanine scan” [Mol. Immunol. 48 (2011) 1844–1850] Molecular Immunology. 53: 173-174. DOI: 10.1016/J.Molimm.2012.07.006  0.732
2013 Smadbeck J, Kieslich CA, Khoury GA, Floudas CA. Novel biclustering framework for tertiary contact prediction using low-homology protein templates Engineering Sciences and Fundamentals 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 2: 616-617.  0.695
2013 Khoury GA, Tamamis P, Pinnaduwage N, Smadbeck J, Kieslich CA, Floudas CA. A novel protein structure refinement method: Blind predictions during CASP10, and an optimized protocol to maximize performance Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 424-425.  0.692
2013 Kieslich CA, Smadbeck J, Khoury GA, Floudas CA. Novel framework for beta-sheet topology prediction using low-homology template-based constraints Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 351-352.  0.644
2012 Kieslich CA, Morikis D. The two sides of complement C3d: evolution of electrostatics in a link between innate and adaptive immunity. Plos Computational Biology. 8: e1002840. PMID 23300422 DOI: 10.1371/Journal.Pcbi.1002840  0.589
2012 López de Victoria A, Tamamis P, Kieslich CA, Morikis D. Insights into the structure, correlated motions, and electrostatic properties of two HIV-1 gp120 V3 loops. Plos One. 7: e49925. PMID 23185486 DOI: 10.1371/Journal.Pone.0049925  0.741
2012 Bellows-Peterson ML, Fung HK, Floudas CA, Kieslich CA, Zhang L, Morikis D, Wareham KJ, Monk PN, Hawksworth OA, Woodruff TM. De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation. Journal of Medicinal Chemistry. 55: 4159-68. PMID 22500977 DOI: 10.1021/Jm201609K  0.771
2012 López de Victoria A, Kieslich CA, Rizos AK, Krambovitis E, Morikis D. Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties. Bmc Biophysics. 5: 3. PMID 22313935 DOI: 10.1186/2046-1682-5-3  0.6
2012 Monk PN, Bellows-Peterson ML, Smadbeck J, Floudas CA, Kieslich CA, Morikis D, Woodruff TM. De novo protein design of agonists and antagonists of C5a receptors Immunobiology. 217: 1162-1163. DOI: 10.1016/J.Imbio.2012.08.097  0.751
2012 Kieslich CA, Lopez de Victoria A, Shin D, Gonzalez-Rivera G, Morikis D. Charge Discriminates Coreceptor Selectivity for HIV-1 Biophysical Journal. 102: 64a. DOI: 10.1016/J.Bpj.2011.11.381  0.605
2012 de Victoria AL, Tamamis P, Gorham RD, Kieslich CA, Bellows-Peterson ML, Floudas CA, Archontis G, Morikis D. Computational and Experimental Analysis of the Interactions Between C3 and Compstatin Family Peptides Biophysical Journal. 102: 62a. DOI: 10.1016/J.Bpj.2011.11.371  0.774
2012 Kieslich CA, Morikis D. The Role of Electrostatics in the Function of Homologous Thioester Containing Proteins: Insights into the Evolution of the Complement C3d:Cr2 Interaction Biophysical Journal. 102: 463a. DOI: 10.1016/J.Bpj.2011.11.2539  0.608
2012 Gorham RD, Kieslich CA, Morikis D. CompleMent Inhibition by Staphylococcus aureus: Electrostatics of C3d-EfbC and C3d-Ehp association Cellular and Molecular Bioengineering. 5: 32-43. DOI: 10.1007/S12195-011-0195-6  0.758
2011 Hakkoymaz H, Kieslich CA, Jr RD, Gunopulos D, Morikis D. Electrostatic Similarity Determination Using Multiresolution Analysis. Molecular Informatics. 30: 733-46. PMID 27467264 DOI: 10.1002/Minf.201100002  0.778
2011 El-Assaad AM, Kieslich CA, Gorham RD, Morikis D. Electrostatic exploration of the C3d-FH4 interaction using a computational alanine scan. Molecular Immunology. 48: 1844-50. PMID 21683447 DOI: 10.1016/J.Molimm.2011.05.007  0.788
2011 Kieslich CA, Vazquez H, Goodman GN, López de Victoria A, Morikis D. The effect of electrostatics on factor H function and related pathologies. Journal of Molecular Graphics & Modelling. 29: 1047-55. PMID 21605993 DOI: 10.1016/J.Jmgm.2011.04.010  0.633
2011 Gorham RD, Kieslich CA, Nichols A, Sausman NU, Foronda M, Morikis D. An evaluation of Poisson-Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data. Biopolymers. 95: 746-54. PMID 21538330 DOI: 10.1002/Bip.21644  0.787
2011 Kieslich CA, Morikis D, Yang J, Gunopulos D. Automated computational framework for the analysis of electrostatic similarities of proteins. Biotechnology Progress. 27: 316-25. PMID 21485028 DOI: 10.1002/Btpr.541  0.684
2011 Gorham RD, Kieslich CA, Morikis D. Electrostatic clustering and free energy calculations provide a foundation for protein design and optimization. Annals of Biomedical Engineering. 39: 1252-63. PMID 21140293 DOI: 10.1007/S10439-010-0226-9  0.804
2011 Kieslich CA, Gorham RD, Morikis D. Is the rigid-body assumption reasonable?: Insights into the effects of dynamics on the electrostatic analysis of barnase-barstar Journal of Non-Crystalline Solids. 357: 707-716. DOI: 10.1016/J.Jnoncrysol.2010.05.087  0.783
2011 Hakkoymaz H, Kieslich CA, Gorham RD, Gunopulos D, Morikis D. Electrostatic similarity determination using multiresolution analysis Molecular Informatics. 30: 733-746. DOI: 10.1002/minf.201100002  0.763
2010 Chae K, Gonong BJ, Kim SC, Kieslich CA, Morikis D, Balasubramanian S, Lord EM. A multifaceted study of stigma/style cysteine-rich adhesin (SCA)-like Arabidopsis lipid transfer proteins (LTPs) suggests diversified roles for these LTPs in plant growth and reproduction. Journal of Experimental Botany. 61: 4277-90. PMID 20667964 DOI: 10.1093/Jxb/Erq228  0.551
2010 Cheung AS, Kieslich CA, Yang J, Morikis D. Solvation effects in calculated electrostatic association free energies for the C3d-CR2 complex and comparison with experimental data. Biopolymers. 93: 509-19. PMID 20091675 DOI: 10.1002/Bip.21388  0.614
2010 Pyaram K, Kieslich CA, Yadav VN, Morikis D, Sahu A. Influence of electrostatics on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus. Journal of Immunology (Baltimore, Md. : 1950). 184: 1956-67. PMID 20089702 DOI: 10.4049/Jimmunol.0903261  0.609
2010 Kieslich CA, Liao J, Morikis D. Development of a High-Throughput Computational Protocol, AESOP, and its Application to the Electrostatic Analysis of the SUMO-1:SENP2 Complex Biophysical Journal. 98: 390a. DOI: 10.1016/J.Bpj.2009.12.2102  0.67
2009 Chae K, Kieslich CA, Morikis D, Kim SC, Lord EM. A gain-of-function mutation of Arabidopsis lipid transfer protein 5 disturbs pollen tube tip growth and fertilization. The Plant Cell. 21: 3902-14. PMID 20044438 DOI: 10.1105/Tpc.109.070854  0.572
2008 Pyaram K, Kieslich C, Yadav VN, Morikis D, Sahu A. Influence of electrostatic potential on the complement regulatory functions of Kaposica, the complement inhibitor of Kaposi's sarcoma-associated herpesvirus Molecular Immunology. 45: 4167-4168. DOI: 10.1016/J.Molimm.2008.08.217  0.558
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