Marc N. Wein, Ph.D. - Publications

Affiliations: 
2007 Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology, Immunology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wein MN. Blood and bones: Mechanical cues and Hippo signaling drive vascular invasion during limb formation. Developmental Cell. 59: 173-174. PMID 38262346 DOI: 10.1016/j.devcel.2023.12.008  0.446
2023 Wang JS, Tokavanich N, Wein MN. SP7: from Bone Development to Skeletal Disease. Current Osteoporosis Reports. PMID 36881265 DOI: 10.1007/s11914-023-00778-7  0.35
2023 Zhou W, Simic P, Zhou IY, Caravan P, Vela Parada X, Wen D, Washington OL, Shvedova M, Pierce KA, Clish CB, Mannstadt M, Kobayashi T, Wein MN, Jüppner H, Rhee EP. Kidney glycolysis serves as a mammalian phosphate sensor that maintains phosphate homeostasis. The Journal of Clinical Investigation. PMID 36821389 DOI: 10.1172/JCI164610  0.301
2022 Sato T, Andrade CDC, Yoon SH, Zhao Y, Greenlee WJ, Weber PC, Viswanathan U, Kulp J, Brooks DJ, Demay MB, Bouxsein ML, Mitlak B, Lanske B, Wein MN. Structure-based design of selective, orally available salt-inducible kinase inhibitors that stimulate bone formation in mice. Proceedings of the National Academy of Sciences of the United States of America. 119: e2214396119. PMID 36472957 DOI: 10.1073/pnas.2214396119  0.52
2022 Mazur CM, Castro Andrade CD, Tokavanich N, Sato T, Bruce M, Brooks DJ, Bouxsein ML, Wang JS, Wein MN. Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy. Iscience. 25: 105019. PMID 36105586 DOI: 10.1016/j.isci.2022.105019  0.49
2022 Yoon SH, Tang CC, Wein MN. Salt inducible kinases and PTH1R action. Vitamins and Hormones. 120: 23-45. PMID 35953111 DOI: 10.1016/bs.vh.2022.04.008  0.35
2022 Daley EJ, Yoon SH, Reyes M, Bruce M, Brooks DJ, Bouxsein M, Potts JT, Kronenberg HM, Wein MN, Lanske B, Jüppner H, Gardella TJ. Actions of Parathyroid Hormone Ligand Analogs in Humanized PTH1R Knock-In Mice. Endocrinology. PMID 35460406 DOI: 10.1210/endocr/bqac054  0.313
2021 Kim PG, Niroula A, Shkolnik V, McConkey M, Lin AE, Słabicki M, Kemp JP, Bick A, Gibson CJ, Griffin G, Sekar A, Brooks DJ, Wong WJ, Cohen DN, Uddin MM, ... ... Wein MN, et al. Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis. The Journal of Experimental Medicine. 218. PMID 34698806 DOI: 10.1084/jem.20211872  0.415
2021 Tang CC, Castro Andrade CD, O'Meara MJ, Yoon SH, Sato T, Brooks DJ, Bouxsein ML, Martins JDS, Wang J, Gray NS, Misof B, Roschger P, Boulin S, Klaushofer K, Velduis-Vlug A, ... ... Wein MN, et al. Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption. Elife. 10. PMID 34160349 DOI: 10.7554/eLife.67772  0.527
2021 Sato T, Verma S, Khatri A, Dean T, Goransson O, Gardella TJ, Wein MN. Comparable Initial Engagement of Intracellular Signaling Pathways by Parathyroid Hormone Receptor Ligands Teriparatide, Abaloparatide, and Long-Acting PTH. Jbmr Plus. 5: e10441. PMID 33977197 DOI: 10.1002/jbm4.10441  0.35
2021 Wang JS, Mazur CM, Wein MN. Sclerostin and Osteocalcin: Candidate Bone-Produced Hormones. Frontiers in Endocrinology. 12: 584147. PMID 33776907 DOI: 10.3389/fendo.2021.584147  0.53
2020 Nishimori S, Wein MN, Kronenberg HM. PTHrP targets salt-inducible kinases, HDAC4 and HDAC5, to repress chondrocyte hypertrophy in the growth plate. Bone. 142: 115709. PMID 33148508 DOI: 10.1016/j.bone.2020.115709  0.354
2020 Wang JS, Yoon SH, Wein MN. Role of histone deacetylases in bone development and skeletal disorders. Bone. 115606. PMID 32829038 DOI: 10.1016/J.Bone.2020.115606  0.443
2020 Sato T, Verma S, Andrade CDC, Omeara M, Campbell N, Wang JS, Cetinbas M, Lang A, Ausk BJ, Brooks DJ, Sadreyev RI, Kronenberg HM, Lagares D, Uda Y, Pajevic PD, ... ... Wein MN, et al. A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction. Nature Communications. 11: 3282. PMID 32612176 DOI: 10.1038/S41467-020-17099-3  0.505
2020 Simic P, Kim W, Zhou W, Pierce KA, Chang W, Sykes DB, Aziz NB, Elmariah S, Ngo D, Pajevic PD, Govea N, Kestenbaum BR, de Boer IH, Cheng Z, Christov M, ... ... Wein MN, et al. Glycerol-3-phosphate is a FGF23 regulator derived from the injured kidney. The Journal of Clinical Investigation. PMID 32065590 DOI: 10.1172/Jci131190  0.398
2019 He Q, Shumate LT, Matthias J, Aydin C, Wein MN, Spatz JM, Goetz R, Mohammadi M, Plagge A, Divieti Pajevic P, Bastepe M. A G protein-coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23. Jci Insight. 4. PMID 31484825 DOI: 10.1172/Jci.Insight.125007  0.452
2019 Nishimori S, O'Meara MJ, Castro C, Noda H, Cetinbas M, da Silva Martins J, Ayturk U, Brooks DJ, Bruce M, Nagata M, Ono W, Janton CJ, Bouxsein ML, Foretz M, Berdeaux R, ... ... Wein MN, et al. Salt-inducible kinases dictate parathyroid hormone receptor action in bone development and remodeling. The Journal of Clinical Investigation. PMID 31430259 DOI: 10.1172/Jci130126  0.554
2019 Sun N, Uda Y, Azab E, Kochen A, Santos RNCE, Shi C, Kobayashi T, Wein MN, Divieti Pajevic P. Effects of histone deacetylase inhibitor Scriptaid and Parathyroid Hormone on osteocyte functions and metabolism. The Journal of Biological Chemistry. PMID 31068415 DOI: 10.1074/Jbc.Ra118.007312  0.511
2018 Wein MN. Parathyroid Hormone Signaling in Osteocytes. Jbmr Plus. 2: 22-30. PMID 30283888 DOI: 10.1002/jbm4.10021  0.494
2018 Wein MN, Foretz M, Fisher DE, Xavier RJ, Kronenberg HM. Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential. Trends in Endocrinology and Metabolism: Tem. PMID 30150136 DOI: 10.1016/J.Tem.2018.08.004  0.38
2018 Wein MN, Kronenberg HM. Regulation of Bone Remodeling by Parathyroid Hormone. Cold Spring Harbor Perspectives in Medicine. PMID 29358318 DOI: 10.1101/Cshperspect.A031237  0.59
2017 He Q, Bouley R, Liu Z, Wein MN, Zhu Y, Spatz JM, Wang CY, Divieti Pajevic P, Plagge A, Babitt JL, Bastepe M. Large G protein α-subunit XLαs limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078380 DOI: 10.1073/Pnas.1712670114  0.33
2017 Tokarz D, Cisek R, Wein MN, Turcotte R, Haase C, Yeh SA, Bharadwaj S, Raphael AP, Paudel H, Alt C, Liu TM, Kronenberg HM, Lin CP. Intravital imaging of osteocytes in mouse calvaria using third harmonic generation microscopy. Plos One. 12: e0186846. PMID 29065178 DOI: 10.1371/Journal.Pone.0186846  0.48
2017 Wein MN. Bone Lining Cells: Normal Physiology and Role in Response to Anabolic Osteoporosis Treatments Current Molecular Biology Reports. 3: 79-84. DOI: 10.1007/s40610-017-0062-x  0.405
2016 Greenblatt MB, Tsai JN, Wein MN. Bone Turnover Markers in the Diagnosis and Monitoring of Metabolic Bone Disease. Clinical Chemistry. PMID 27940448 DOI: 10.1373/Clinchem.2016.259085  0.524
2016 Kim SW, Lu Y, Williams EA, Lai F, Lee JY, Enishi T, Balani DH, Ominsky MS, Ke HZ, Kronenberg HM, Wein MN. Sclerostin Antibody Administration Converts Bone Lining Cells into Active Osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27862326 DOI: 10.1002/Jbmr.3038  0.54
2016 Wein MN, Liang Y, Goransson O, Sundberg TB, Wang J, Williams EA, O'Meara MJ, Govea N, Beqo B, Nishimori S, Nagano K, Brooks DJ, Martins JS, Corbin B, Anselmo A, et al. SIKs control osteocyte responses to parathyroid hormone. Nature Communications. 7: 13176. PMID 27759007 DOI: 10.1038/Ncomms13176  0.53
2016 Fulzele K, Lai F, Dedic C, Saini V, Uda Y, Shi C, Tuck P, Aronson JL, Liu X, Spatz JM, Wein M, Pajevic PD. Osteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27653320 DOI: 10.1002/Jbmr.3001  0.417
2016 Eda H, Santo L, Wein MN, Hu DZ, Cirstea DD, Nemani N, Tai YT, Raines SE, Kuhstoss SA, Munshi NC, Kronenberg HM, Raje NS. Regulation of Sclerostin Expression in Multiple Myeloma by Dkk-1; A Potential Therapeutic Strategy for Myeloma Bone Disease. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26763740 DOI: 10.1002/Jbmr.2789  0.53
2015 Spatz JM, Wein MN, Gooi JH, Qu Y, Garr JL, Liu S, Barry KJ, Uda Y, Lai F, Dedic C, Balcells-Camps M, Kronenberg HM, Babij P, Pajevic PD. The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytes in Vitro. The Journal of Biological Chemistry. 290: 16744-58. PMID 25953900 DOI: 10.1074/Jbc.M114.628313  0.551
2015 Papaioannou G, Mirzamohammadi F, Lisse TS, Nishimori S, Wein MN, Kobayashi T. MicroRNA-140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP-HDAC4 Pathway. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 1044-52. PMID 25529628 DOI: 10.1002/Jbmr.2438  0.345
2015 Wein MN, Spatz J, Nishimori S, Doench J, Root D, Babij P, Nagano K, Baron R, Brooks D, Bouxsein M, Pajevic PD, Kronenberg HM. HDAC5 controls MEF2C-driven sclerostin expression in osteocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 400-11. PMID 25271055 DOI: 10.1002/Jbmr.2381  0.53
2015 Pajevic PD, Wein MN, Kronenberg HM. Parathyroid hormone actions on bone and kidney Hypoparathyroidism. 99-109. DOI: 10.1007/978-88-470-5376-2_11  0.412
2013 Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. The Journal of Clinical Investigation. 123: 4010-22. PMID 23945236 DOI: 10.1172/Jci69443  0.669
2012 Wein MN, Jones DC, Shim JH, Aliprantis AO, Sulyanto R, Lazarevic V, Poliachik SL, Gross TS, Glimcher LH. Control of bone resorption in mice by Schnurri-3. Proceedings of the National Academy of Sciences of the United States of America. 109: 8173-8. PMID 22573816 DOI: 10.1073/Pnas.1205848109  0.695
2010 Jones DC, Schweitzer MN, Wein M, Sigrist K, Takagi T, Ishii S, Glimcher LH. Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3. Proceedings of the National Academy of Sciences of the United States of America. 107: 8254-8. PMID 20404140 DOI: 10.1073/Pnas.1003727107  0.652
2009 Hofstaetter J, Roschger P, Jones D, Zoehrer R, Seto J, Wein M, Glimcher M, Paschalis E, Fratzl P, Glimcher L, Klaushofer K. Increased bone mass and bone matrix mineralization in schnurri-3 null mice Bone. 44: S249. DOI: 10.1016/J.Bone.2009.03.121  0.576
2009 Hofstaetter J, Roschger P, Jones D, Zoehrer R, Seto J, Wein M, Glimcher M, Paschalis E, Fratzl P, Glimcher L, Klaushofer K. Increased bone matrix mineralization in Schnurri-3 null mice Bone. 44: S147-S148. DOI: 10.1016/J.Bone.2009.01.322  0.54
2008 Wein MN, Jones DC, Glimcher LH. Lentivirus delivery of shRNA constructs into osteoblasts. Methods in Molecular Biology (Clifton, N.J.). 455: 149-55. PMID 18463817 DOI: 10.1007/978-1-59745-104-8_11  0.594
2008 Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, et al. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. The Journal of Clinical Investigation. 118: 491-504. PMID 18219387 DOI: 10.1172/Jci33102  0.631
2007 Glimcher LH, Jones DC, Wein MN. Control of postnatal bone mass by the zinc finger adapter protein Schnurri-3. Annals of the New York Academy of Sciences. 1116: 174-81. PMID 18083927 DOI: 10.1196/Annals.1402.044  0.686
2007 Jones DC, Wein MN, Glimcher LH. Schnurri-3: a key regulator of postnatal skeletal remodeling. Advances in Experimental Medicine and Biology. 602: 1-13. PMID 17966382 DOI: 10.1007/978-0-387-72009-8_1  0.684
2007 Jones DC, Wein MN, Glimcher LH. Schnurri-3 is an essential regulator of osteoblast function and adult bone mass. Annals of the Rheumatic Diseases. 66: iii49-51. PMID 17934096 DOI: 10.1136/Ard.2007.078352  0.685
2006 Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, Glimcher LH. Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science (New York, N.Y.). 312: 1223-7. PMID 16728642 DOI: 10.1126/Science.1126313  0.687
2005 Wein MN, Jones DC, Glimcher LH. Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity. Immunological Reviews. 208: 66-79. PMID 16313341 DOI: 10.1111/J.0105-2896.2005.00322.X  0.581
2004 Oukka M, Wein MN, Glimcher LH. Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells. The Journal of Experimental Medicine. 199: 15-24. PMID 14707112 DOI: 10.1084/Jem.20030421  0.484
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