| Year |
Citation |
Score |
| 2005 |
Baer BR, Rettie AE, Henne KR. Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate. Chemical Research in Toxicology. 18: 855-64. PMID 15892579 DOI: 10.1021/tx0496993 |
0.501 |
|
| 2003 |
Zheng YM, Baer BR, Kneller MB, Henne KR, Kunze KL, Rettie AE. Covalent heme binding to CYP4B1 via Glu310 and a carbocation porphyrin intermediate. Biochemistry. 42: 4601-6. PMID 12693958 DOI: 10.1021/Bi020667T |
0.598 |
|
| 2003 |
Zheng YM, Henne KR, Charmley P, Kim RB, McCarver DG, Cabacungan ET, Hines RN, Rettie AE. Genotyping and site-directed mutagenesis of a cytochrome P450 meander Pro-X-Arg motif critical to CYP4B1 catalysis. Toxicology and Applied Pharmacology. 186: 119-26. PMID 12639503 DOI: 10.1016/S0041-008X(02)00028-5 |
0.581 |
|
| 2003 |
Zheng Y, Baer B, Kneller M, Henne K, Kunze K, Rettie A. 559 Mechanistic studies of covalent heme binding to CYP4B1 Toxicology Letters. 144: s150. DOI: 10.1016/S0378-4274(03)90558-3 |
0.471 |
|
| 2001 |
Henne KR, Kunze KL, Zheng YM, Christmas P, Soberman RJ, Rettie AE. Covalent linkage of prosthetic heme to CYP4 family P450 enzymes. Biochemistry. 40: 12925-31. PMID 11669629 DOI: 10.1021/Bi011171Z |
0.572 |
|
| 2001 |
Henne KR, Fisher MB, Iyer KR, Lang DH, Trager WF, Rettie AE. Active site characteristics of CYP4B1 probed with aromatic ligands. Biochemistry. 40: 8597-605. PMID 11456500 DOI: 10.1021/Bi010395E |
0.588 |
|
| 1999 |
Haining RL, Jones JP, Henne KR, Fisher MB, Koop DR, Trager WF, Rettie AE. Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding. Biochemistry. 38: 3285-92. PMID 10079071 DOI: 10.1021/Bi982161+ |
0.627 |
|
| 1998 |
Henne KR, Gaedigk A, Gupta G, Leeder JS, Rettie AE. Chiral phase analysis of warfarin enantiomers in patient plasma in relation to CYP2C9 genotype. Journal of Chromatography. B, Biomedical Sciences and Applications. 710: 143-8. PMID 9686881 DOI: 10.1016/S0378-4347(98)00099-1 |
0.535 |
|
| 1997 |
Steward DJ, Haining RL, Henne KR, Davis G, Rushmore TH, Trager WF, Rettie AE. Genetic association between sensitivity to warfarin and expression of CYP2C9*3. Pharmacogenetics. 7: 361-7. PMID 9352571 DOI: 10.1097/00008571-199710000-00004 |
0.595 |
|
| 1997 |
Haining RL, Steward DJ, Henne KR, Davis GA, Rettie A. Correlation of the cytochrome P450 2C9 LeuA9 defect with warfarin sensitivity Faseb Journal. 11. |
0.312 |
|
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