| Year |
Citation |
Score |
| 2006 |
Trnka MJ, Doneanu CE, Trager WF. Photoaffinity labeling of P450Cam by an imidazole-tethered benzophenone probe. Archives of Biochemistry and Biophysics. 445: 95-107. PMID 16321358 DOI: 10.1016/J.Abb.2005.10.014 |
0.706 |
|
| 2004 |
Suzuki H, Kneller MB, Rock DA, Jones JP, Trager WF, Rettie AE. Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors. Archives of Biochemistry and Biophysics. 429: 1-15. PMID 15288804 DOI: 10.1016/J.Abb.2004.05.015 |
0.554 |
|
| 2003 |
Nelson SD, Trager WF. The use of deuterium isotope effects to probe the active site properties, mechanism of cytochrome P450-catalyzed reactions, and mechanisms of metabolically dependent toxicity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1481-98. PMID 14625345 DOI: 10.1124/Dmd.31.12.1481 |
0.55 |
|
| 2002 |
Lightning LK, Trager WF. Characterization of covalent adducts to intact cytochrome P450s by mass spectrometry. Methods in Enzymology. 357: 296-300. PMID 12424919 DOI: 10.1016/S0076-6879(02)57687-4 |
0.344 |
|
| 2002 |
Suzuki H, Kneller MB, Haining RL, Trager WF, Rettie AE. (+)-N-3-Benzyl-nirvanol and (-)-N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 235-9. PMID 11854139 DOI: 10.1124/Dmd.30.3.235 |
0.552 |
|
| 2001 |
Henne KR, Fisher MB, Iyer KR, Lang DH, Trager WF, Rettie AE. Active site characteristics of CYP4B1 probed with aromatic ligands. Biochemistry. 40: 8597-605. PMID 11456500 DOI: 10.1021/Bi010395E |
0.743 |
|
| 2001 |
He M, Rettie AE, Neal J, Trager WF. Metabolism of sulfinpyrazone sulfide and sulfinpyrazone by human liver microsomes and cDNA-expressed cytochrome P450s. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 29: 701-11. PMID 11302937 |
0.545 |
|
| 2000 |
Rao S, Aoyama R, Schrag M, Trager WF, Rettie A, Jones JP. A refined 3-dimensional QSAR of cytochrome P450 2C9: computational predictions of drug interactions. Journal of Medicinal Chemistry. 43: 2789-96. PMID 10956186 DOI: 10.1021/Jm000048N |
0.532 |
|
| 2000 |
Lightning LK, Jones JP, Friedberg T, Pritchard MP, Shou M, Rushmore TH, Trager WF. Mechanism-based inactivation of cytochrome P450 3A4 by L-754,394. Biochemistry. 39: 4276-87. PMID 10757976 DOI: 10.1021/Bi992412U |
0.326 |
|
| 1999 |
He M, Korzekwa KR, Jones JP, Rettie AE, Trager WF. Structural forms of phenprocoumon and warfarin that are metabolized at the active site of CYP2C9. Archives of Biochemistry and Biophysics. 372: 16-28. PMID 10562412 DOI: 10.1006/Abbi.1999.1468 |
0.57 |
|
| 1999 |
Haining RL, Jones JP, Henne KR, Fisher MB, Koop DR, Trager WF, Rettie AE. Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding. Biochemistry. 38: 3285-92. PMID 10079071 DOI: 10.1021/Bi982161+ |
0.736 |
|
| 1999 |
Koenigs LL, Peter RM, Hunter AP, Haining RL, Rettie AE, Friedberg T, Pritchard MP, Shou M, Rushmore TH, Trager WF. Electrospray ionization mass spectrometric analysis of intact cytochrome P450: identification of tienilic acid adducts to P450 2C9. Biochemistry. 38: 2312-9. PMID 10029524 DOI: 10.1021/Bi9823030 |
0.554 |
|
| 1999 |
Audergon C, Iyer KR, Jones JP, Darbyshire JF, Trager WF. Experimental and Theoretical Study of the Effect of Active-Site Constrained Substrate Motion on the Magnitude of the Observed Intramolecular Isotope Effect for the P450 101 Catalyzed Benzylic Hydroxylation of Isomeric Xylenes and 4,4‘-Dimethylbiphenyl Journal of the American Chemical Society. 121: 41-47. DOI: 10.1021/Ja983000W |
0.353 |
|
| 1998 |
Chen W, Koenigs LL, Thompson SJ, Peter RM, Rettie AE, Trager WF, Nelson SD. Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6 Chemical Research in Toxicology. 11: 295-301. PMID 9548799 DOI: 10.1021/Tx9701687 |
0.643 |
|
| 1997 |
Koenigs LL, Peter RM, Thompson SJ, Rettie AE, Trager WF. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 25: 1407-15. PMID 9394031 |
0.491 |
|
| 1997 |
Steward DJ, Haining RL, Henne KR, Davis G, Rushmore TH, Trager WF, Rettie AE. Genetic association between sensitivity to warfarin and expression of CYP2C9*3. Pharmacogenetics. 7: 361-7. PMID 9352571 DOI: 10.1097/00008571-199710000-00004 |
0.724 |
|
| 1997 |
Iyer KR, Jones JP, Darbyshire JF, Trager WF. Intramolecular isotope effects for benzylic hydroxylation of isomeric xylenes and 4,4'-dimethylbiphenyl by cytochrome P450: relationship between distance of methyl groups and masking of the intrinsic isotope effect. Biochemistry. 36: 7136-43. PMID 9188713 DOI: 10.1021/Bi962810M |
0.381 |
|
| 1997 |
Trager WF. Chapter 15 Biotransformation and excretion: Mechanistic studies: Deuterium isotope effects as a probe of the catalytic properties of the cytochromes P450 Pharmacochemistry Library. 26: 275-296. DOI: 10.1016/S0165-7208(97)80162-6 |
0.358 |
|
| 1996 |
Jones JP, He M, Trager WF, Rettie AE. Three-dimensional quantitative structure-activity relationship for inhibitors of cytochrome P4502C9. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 24: 1-6. PMID 8825183 |
0.444 |
|
| 1996 |
Haining RL, Hunter AP, Veronese ME, Trager WF, Rettie AE. Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms. Archives of Biochemistry and Biophysics. 333: 447-58. PMID 8809086 DOI: 10.1006/Abbi.1996.0414 |
0.562 |
|
| 1996 |
Wienkers LC, Wurden CJ, Storch E, Kunze KL, Rettie AE, Trager WF. Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 24: 610-4. PMID 8723744 |
0.501 |
|
| 1995 |
Korzekwa KR, Gillette JR, Trager WF. Isotope effect studies on the cytochrome P450 enzymes. Drug Metabolism Reviews. 27: 45-59. PMID 7641584 DOI: 10.3109/03602539509029814 |
0.344 |
|
| 1994 |
Wang JP, Unadkat JD, McNamara S, O'Sullivan TA, Smith AL, Trager WF, Ramsey B. Disposition of drugs in cystic fibrosis. VI. In vivo activity of cytochrome P450 isoforms involved in the metabolism of (R)-warfarin (including P450 3A4) is not enhanced in cystic fibrosis. Clinical Pharmacology and Therapeutics. 55: 528-34. PMID 8181197 DOI: 10.1038/Clpt.1994.66 |
0.339 |
|
| 1994 |
Rettie AE, Wienkers LC, Gonzalez FJ, Trager WF, Korzekwa KR. Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9. Pharmacogenetics. 4: 39-42. PMID 8004131 DOI: 10.1097/00008571-199402000-00005 |
0.516 |
|
| 1994 |
Hall SD, Hamman MA, Rettie AE, Wienkers LC, Trager WF, Vandenbranden M, Wrighton SA. Relationships between the levels of cytochrome P4502C9 and its prototypic catalytic activities in human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 22: 975-8. PMID 7895619 |
0.447 |
|
| 1993 |
Korzekwa KR, Trager WF, Mancewicz J, Osawa Y. Studies on the mechanism of aromatase and other cytochrome P450 mediated deformylation reactions. The Journal of Steroid Biochemistry and Molecular Biology. 44: 367-73. PMID 8476750 DOI: 10.1016/0960-0760(93)90240-W |
0.321 |
|
| 1992 |
Rettie AE, Korzekwa KR, Kunze KL, Lawrence RF, Craig Eddy A, Aoyama T, Gelboin HV, Gonzalez FJ, Trager WF. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: A role for P-4502C9 in the etiology of (S)-warfarin - Drug interactions Chemical Research in Toxicology. 5: 54-59. PMID 1581537 DOI: 10.1021/Tx00025A009 |
0.572 |
|
| 1991 |
Kunze KL, Eddy AC, Gibaldi M, Trager WF. Metabolic enantiomeric interactions: the inhibition of human (S)-warfarin-7-hydroxylase by (R)-warfarin. Chirality. 3: 24-9. PMID 2039681 DOI: 10.1002/Chir.530030106 |
0.346 |
|
| 1990 |
Korzekwa KR, Swinney DC, Trager WF. Isotopically labeled chlorobenzenes as probes for the mechanism of cytochrome P-450 catalyzed aromatic hydroxylation. Biochemistry. 28: 9019-27. PMID 2605239 DOI: 10.1021/Bi00449A010 |
0.356 |
|
| 1990 |
Lawrence RF, Rettie AE, Eddy AC, Trager WF. Chemical synthesis, absolute configuration, and stereochemistry of formation of 10-hydroxywarfarin: a major oxidative metabolite of (+)-(R)-warfarin from hepatic microsomal preparations. Chirality. 2: 96-105. PMID 2400642 DOI: 10.1002/Chir.530020207 |
0.561 |
|
| 1990 |
Jones JP, Rettie AE, Trager WF. Intrinsic isotope effects suggest that the reaction coordinate symmetry for the cytochrome P-450 catalyzed hydroxylation of octane is isozyme independent. Journal of Medicinal Chemistry. 33: 1242-6. PMID 2319565 DOI: 10.1021/Jm00166A024 |
0.579 |
|
| 1990 |
Ottoboni S, Carlson TJ, Trager WF, Castagnoli K, Castagnoli N. Studies on the cytochrome P-450 catalyzed ring alpha-carbon oxidation of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Chemical Research in Toxicology. 3: 423-7. PMID 2133093 DOI: 10.1021/Tx00017A006 |
0.379 |
|
| 1989 |
Korzekwa K, Nagata K, Trager WF, Gillette JR. Metabolism of the B-ring of testosterone by the rat cytochrome P-450 system. Drug Metabolism Reviews. 20: 535-9. PMID 2680396 DOI: 10.3109/03602538909103559 |
0.303 |
|
| 1989 |
Trager WF. Stereochemistry of cytochrome P-450 reactions. Drug Metabolism Reviews. 20: 489-96. PMID 2680392 DOI: 10.3109/03602538909103555 |
0.333 |
|
| 1989 |
Korzekwa KR, Trager WF, Gillette JR. Theory for the observed isotope effects from enzymatic systems that form multiple products via branched reaction pathways: cytochrome P-450. Biochemistry. 28: 9012-8. PMID 2605238 DOI: 10.1021/Bi00449A009 |
0.339 |
|
| 1989 |
Rettie AE, Eddy AC, Heimark LD, Gibaldi M, Trager WF. Characteristics of warfarin hydroxylation catalyzed by human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 17: 265-70. PMID 2568906 |
0.525 |
|
| 1987 |
Sugiyama K, Trager WF. Prochiral selectivity and intramolecular isotope effects in the cytochrome P-450 catalyzed omega-hydroxylation of cumene. Biochemistry. 25: 7336-43. PMID 3801417 DOI: 10.1021/Bi00371A015 |
0.383 |
|
| 1987 |
Correia MA, Decker C, Sugiyama K, Caldera P, Bornheim L, Wrighton SA, Rettie AE, Trager WF. Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts. Archives of Biochemistry and Biophysics. 258: 436-51. PMID 3674884 DOI: 10.1016/0003-9861(87)90365-1 |
0.561 |
|
| 1987 |
O'Reilly RA, Trager WF, Rettie AE, Goulart DA. Interaction of amiodarone with racemic warfarin and its separated enantiomorphs in humans. Clinical Pharmacology and Therapeutics. 42: 290-4. PMID 3621782 DOI: 10.1038/Clpt.1987.149 |
0.507 |
|
| 1987 |
Bornheim LM, Underwood MC, Caldera P, Rettie AE, Trager WF, Wrighton SA, Correia MA. Inactivation of multiple hepatic cytochrome P-450 isozymes in rats by allylisopropylacetamide: mechanistic implications. Molecular Pharmacology. 32: 299-308. PMID 3302670 |
0.494 |
|
| 1987 |
Jones JP, Trager WF. The separation of the intramolecular isotope effect for the cytochrome P-450 catalyzed hydroxylation of n-octane into its primary and secondary components Journal of the American Chemical Society. 109: 2171-2173. DOI: 10.1021/Ja00241A040 |
0.323 |
|
| 1987 |
JONES JP, KORZEKWA KR, RETTIE AE, TRAGER WF. ChemInform Abstract: Isotopically Sensitive Branching and Its Effect on the Observed Intramolecular Isotope Effects in Cytochrome P-450 Catalyzed Reactions: A New Method for the Estimation of Intrinsic Isotope Effects. Cheminform. 18. DOI: 10.1002/chin.198712138 |
0.496 |
|
| 1986 |
Toon S, Heimark LD, Trager WF, O'Reilly RA. Metabolic fate of phenprocoumon in humans. Journal of Pharmaceutical Sciences. 74: 1037-40. PMID 4078699 DOI: 10.1002/Jps.2600741003 |
0.314 |
|
| 1986 |
Jones JP, Korzekwa KR, Rettie AE, Trager WF. Isotopically sensitive branching and its effect on the observed intramolecular isotope effects in cytochrome P-450 catalyzed reactions: a new method for the estimation of intrinsic isotope effects Journal of the American Chemical Society. 108: 7074-7078. DOI: 10.1021/Ja00282A037 |
0.555 |
|
| 1986 |
Heimark LD, Toon S, Low LK, Swinney DC, Trager WF. The synthesis of deuterium labelled metabolites of warfarin and phenprocoumon Journal of Labelled Compounds and Radiopharmaceuticals. 23: 137-148. DOI: 10.1002/Jlcr.2580230204 |
0.327 |
|
| 1985 |
Rettie AE, Heimark L, Mayer RT, Burke MD, Trager WF, Juchau MR. Stereoselective and regioselective hydroxylation of warfarin and selective O-dealkylation of phenoxazone ethers in human placenta. Biochemical and Biophysical Research Communications. 126: 1013-21. PMID 3977899 DOI: 10.1016/0006-291X(85)90286-4 |
0.673 |
|
| 1985 |
Heimark LD, Trager WF. A stable isotope assay for phenprocoumon and its metabolites. Biomedical Mass Spectrometry. 12: 67-71. PMID 3158358 DOI: 10.1002/Bms.1200120204 |
0.308 |
|
| 1985 |
Korzekwa K, Trager W, Gouterman M, Spangler D, Loew GH. Cytochrome P450 mediated aromatic oxidation: A theoretical study Journal of the American Chemical Society. 107: 4273-4279. DOI: 10.1002/Chin.198544102 |
0.301 |
|
| 1984 |
Swinney DC, Howald WN, Trager WF. Intramolecular isotope effects associated with meta-hydroxylation of biphenyl catalyzed by cytochrome P-450. Biochemical and Biophysical Research Communications. 118: 867-72. PMID 6704111 DOI: 10.1016/0006-291X(84)91475-X |
0.361 |
|
| 1982 |
Bush ED, Trager WF. Evidence against an abstraction or direct insertion mechanism for cytochrome P-450 catalysed meta hydroxylations. Biochemical and Biophysical Research Communications. 104: 626-32. PMID 7073704 DOI: 10.1016/0006-291X(82)90683-0 |
0.339 |
|
| 1981 |
Porter WR, Wheeler C, Trager WF. Changes in the metabolic profiles of R- and S-warfarin and R- and S-phenprocoumon as a probe to categorize the effect of inducing agents on microsomal hydroxylases. Biochemical Pharmacology. 30: 3099-104. PMID 7337727 DOI: 10.1016/0006-2952(81)90499-8 |
0.367 |
|
| 1981 |
Wheeler C, Trager WF, Porter WR. Stereochemical aspects of the metabolism of phenprocoumon in rat liver microsomes. Biochemical Pharmacology. 30: 1785-90. PMID 7271865 DOI: 10.1016/0006-2952(81)90011-3 |
0.355 |
|
| 1980 |
O'Reilly RA, Trager WF, Motley CH, Howald W. Interaction of secobarbital with warfarin pseudoracemates. Clinical Pharmacology and Therapeutics. 28: 187-95. PMID 7398186 DOI: 10.1038/Clpt.1980.149 |
0.32 |
|
| 1978 |
Nelson SD, Nelson WL, Trager WF. N-hydroxyamide metabolites of lidocaine. Synthesis, characterization, quantitation, and mutagenic potential Journal of Medicinal Chemistry. 21: 721-725. PMID 690997 DOI: 10.1002/Chin.197851153 |
0.495 |
|
| 1978 |
Valente EJ, Porter WR, Trager WF. Conformations of selected 3-substituted 4-hydroxycoumarins in solution by nuclear magnetic resonance. Warfarin and phenprocoumon. Journal of Medicinal Chemistry. 21: 231-4. PMID 621721 DOI: 10.1002/Chin.197825315 |
0.307 |
|
| 1977 |
Porter WR, Branchflower RV, Trager WF. A kinetic method for the determination of the multiple forms of microsomal cytochrome P-450. Biochemical Pharmacology. 26: 549-50. PMID 849353 DOI: 10.1016/0006-2952(77)90334-3 |
0.321 |
|
| 1977 |
Nelson SD, Garland WA, Breck GD, Trager WF. Quantification of lidocaine and several metabolites utilizing chemical ionization mass spectrometry and stable isotope labeling Journal of Pharmaceutical Sciences. 66: 1180-1190. PMID 408479 DOI: 10.1002/Jps.2600660834 |
0.526 |
|
| 1976 |
Pohl LR, Nelson SD, Porter WR, Trager WF, Fasco MJ, Baker FD, Fenton JW. Warfarin-stereochemical aspects of its metabolism by rat liver microsomes. Biochemical Pharmacology. 25: 2153-62. PMID 971329 |
0.417 |
|
| 1975 |
Nelson SD, Pohl LR, Trager WF. Primary and β-secondary deuterium isotope effects in N-deethylation reactions Journal of Medicinal Chemistry. 18: 1062-1065. PMID 1177251 DOI: 10.1021/Jm00245A003 |
0.517 |
|
| 1975 |
Pohl LR, Nelson SD, Garland WA, Trager WF. The rapid identification of a new metabolite of warfarin via a chemical ionization mass spectrometry ion doublet technique. Biomedical Mass Spectrometry. 2: 23-30. PMID 1131390 DOI: 10.1002/Bms.1200020106 |
0.496 |
|
| 1974 |
Garland WA, Trager WF, Nelson SD. Direct (non-chromatographic) quantification of drugs and their metabolites from human plasma utilizing chemical ionization mass spectrometry and stable isotope labeling: quinidine and lidocaine Biomedical Mass Spectrometry. 1: 124-129. PMID 4433724 DOI: 10.1002/Bms.1200010208 |
0.512 |
|
| 1973 |
Nelson SD, Kollman PA, Trager WF, Rothenberg S. Molecular orbital calculations on suspected intermediates in oxidative amine metabolism Journal of Medicinal Chemistry. 16: 1034-1037. PMID 4745504 DOI: 10.1021/Jm00267A017 |
0.493 |
|
| 1973 |
Nelson SD, Breck GD, Trager WF. In vivo metabolite condensations. Formation of N1-Ethyl-2-methyl-N 3-(2,6-dimethylphenyl)-4-imidazolidinone from the reaction of a metabolite of alcohol with a metabolite of lidocaine Journal of Medicinal Chemistry. 16: 1106-1112. PMID 4201421 DOI: 10.1002/Chin.197404394 |
0.509 |
|
| 1973 |
NELSON SD, KOLLMAN PA, TRAGER WF, ROTHENBERG S. ChemInform Abstract: MOLECULAR ORBITAL CALCULATIONS ON SUSPECTED INTERMEDIATES IN OXIDATIVE AMINE METABOLISM Chemischer Informationsdienst. 4. DOI: 10.1002/Chin.197351188 |
0.499 |
|
| 1972 |
Nelson SD, Kasparian DJ, Trager WF. Reaction of .alpha.-nitro ketones with the ketene-generating compounds, isopropenyl acetate and .alpha.-acetoxystyrene. Synthesis of 3-acetyl- and 3-benzoyl-5-substituted isoxazoles The Journal of Organic Chemistry. 37: 2686-2688. DOI: 10.1021/Jo00982A012 |
0.477 |
|
| 1972 |
NELSON SD, KASPARIAN DJ, TRAGER WF. ChemInform Abstract: DIE RK. VON ALPHA-NITRO-KETONEN MIT KETEN-BILDENDEN REAGENTIEN, ISOPROPENYLACETAT UND ALPHA-ACETOXY-STYROL, SYNTH. VON 3-ACETYL- UND 3-BENZOYL-5-SUBSTITUIERTEN-ISOXAZOLEN Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197247334 |
0.447 |
|
| 1968 |
Trager WF, Phillipson JD, Beckett AH. Chemical confirmation for the configurations assigned to the indole alkaloids, speciogynine, speciociliatine, mitraciliatine and hirsutine. Tetrahedron. 24: 2681-5. PMID 5641278 DOI: 10.1016/S0040-4020(01)82542-4 |
0.44 |
|
| 1968 |
Trager WF, Lee CM, Phillipson JD, Haddock RE, Dwuma-Badu D, Beckett AH. Configurational analysis of rhynchophylline-type oxindole alkaloids. The absolute configuration of ciliaphylline, rhynchociline, specionoxeine, isospecionoxeine, rotundifoline and isorotundifoline. Tetrahedron. 24: 523-43. PMID 5637484 DOI: 10.1016/0040-4020(68)88002-0 |
0.422 |
|
| 1967 |
Trager WF, Huitric AC. Conformational analysis of 4-hydroxycyclohexanone oxime by NMR spectroscopy. Journal of Pharmaceutical Sciences. 56: 1111-1114. PMID 6049696 DOI: 10.1002/Jps.2600560913 |
0.616 |
|
| 1967 |
Lee CM, Trager WF, Beckett AH. Corynantheidine-type alkaloids. II. Absolute configuration of mitragynine, speciociliatine, mitraciliatine and speciogynine. Tetrahedron. 23: 375-85. PMID 6037287 DOI: 10.1016/S0040-4020(01)83323-8 |
0.438 |
|
| 1967 |
Trager WF, Lee CM, Beckett AH. Corynantheidine-type alkaloids. I. Establishment of physical criteria for the normal, pseudo, allo and epiallo configurations by conformational analysis. Tetrahedron. 23: 365-74. PMID 6037286 DOI: 10.1016/S0040-4020(01)83322-6 |
0.455 |
|
| 1967 |
Trager WF, Nist BJ, Huitric AC. NMR conformational analysis of 4-hydroxycyclohexanone and 1,4-cyclohexanediols. Coupling constants averaging induced by conformational equilibria and by strong coupling effects--role of solvent. Journal of Pharmaceutical Sciences. 56: 698-704. PMID 6034801 DOI: 10.1002/Jps.2600560607 |
0.596 |
|
| 1967 |
Trager W, Lee C, Phillipson J, Beckett A. The absolute configuration of paynantheine and hirsutine Tetrahedron. 23: 1043-1047. DOI: 10.1016/0040-4020(67)85052-X |
0.44 |
|
| 1966 |
Huitric AC, Carr JB, Trager WF. NMR 1,3-diaxial deshielding effect of the hydroxyl group on ring hydrogens studied from partially deuterated six-membered ring compounds. Journal of Pharmaceutical Sciences. 55: 211-213. PMID 5923274 DOI: 10.1002/Jps.2600550219 |
0.62 |
|
| 1966 |
Trager WF, Huitric AC. Long-range shielding effects of the oximido group in 4-tert-butylcyclohexanone oxime Tetrahedron Letters. 7: 825-829. DOI: 10.1016/S0040-4039(01)99691-1 |
0.565 |
|
| 1965 |
TRAGER WF, NIST BJ, HUITRIC AC. SOLVENT EFFECTS IN CONFORMATIONAL ANALYSIS OF 1,4-CYCLOHEXANEDIOLS. Tetrahedron Letters. 57: 267-73. PMID 14268143 DOI: 10.1016/S0040-4039(00)89952-9 |
0.599 |
|
| 1965 |
Trager WF, Huitric AC. Cis- and trans-2-(3,4,5-Trimethoxyphenyl)cyclohexylamine. Journal of Pharmaceutical Sciences. 54: 1552-3. PMID 5883243 DOI: 10.1002/Jps.2600541040 |
0.576 |
|
| 1965 |
Trager WF, Huitric AC. The Conformational Free-Energy Difference of the Nitro Group The Journal of Organic Chemistry. 30: 3257-3257. DOI: 10.1021/jo01020a538 |
0.537 |
|
| 1965 |
Trager WF, Huitric AC. The conformational free-energy difference of the nitro group Journal of Organic Chemistry. 30: 3257. DOI: 10.1021/Jo01020A538 |
0.575 |
|
| 1965 |
Trager W, Nist B, Huitric A. Solvent effects in conformational analysis of 4-hydroxycyclohexanone Tetrahedron Letters. 6: 2931-2936. DOI: 10.1016/S0040-4039(00)90239-9 |
0.563 |
|
| 1965 |
Trager WF, Nist BJ, Huitric AC. Solvent effects in conformational analysis of 4-hydroxycyclohexanone Tetrahedron Letters. 6: 2931-2936. DOI: 10.1016/S0040-4039(00)90239-9 |
0.599 |
|
| 1963 |
Huitric A, Carr J, Trager W, Nist B. Configurational and conformational analysis Tetrahedron. 19: 2145-2151. DOI: 10.1016/0040-4020(63)85029-2 |
0.556 |
|
| 1963 |
Huitric AC, Carr JB, Trager WF, Nist BJ. Configurational and conformational analysis. Axial-axial and axial-equatorial coupling constants in six-membered ring compounds Tetrahedron. 19: 2145-2151. DOI: 10.1016/0040-4020(63)85029-2 |
0.61 |
|
| 1962 |
Trager WF, Vincenzi FF, Huitric AC. Proton magnetic resonance spectra, stereochemistry, and synthesis of 2-arylnitrocyclohexanes and 2-arylcyclohexylamines Journal of Organic Chemistry. 27: 3006-3010. DOI: 10.1021/Jo01056A007 |
0.561 |
|
| Show low-probability matches. |
