Charles A. Scanga, Ph.D. - Publications

Affiliations: 
2000 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Microbiology Biology, Immunology

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jauro S, Larson EC, Gleim JL, Wahlberg BM, Rodgers MA, Chehab JC, Lopez-Velazques AE, Ameel CL, Tomko JA, Sakal JL, DeMarco T, Borish HJ, Maiello P, Potter EL, Roederer M, ... ... Scanga CA, et al. Intravenous Bacillus Calmette-Guérin (BCG) Induces a More Potent Airway and Lung Immune Response than Intradermal BCG in Simian Immunodeficiency Virus-infected Macaques. Journal of Immunology (Baltimore, Md. : 1950). PMID 39311665 DOI: 10.4049/jimmunol.2400417  0.625
2024 Bromley JD, Ganchua SKC, Nyquist SK, Maiello P, Chao M, Borish HJ, Rodgers M, Tomko J, Kracinovsky K, Mugahid D, Nguyen S, Wang QD, Rosenberg JM, Klein EC, Gideon HP, ... ... Scanga CA, et al. CD4 T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection. Immunity. PMID 39214090 DOI: 10.1016/j.immuni.2024.08.002  0.617
2024 Jauro S, Larson EC, Gleim JL, Wahlberg BM, Rodgers MA, Chehab JC, Lopez-Velazques AE, Ameel CL, Tomko JA, Sakal JL, DeMarco T, Borish HJ, Maiello P, Potter EL, Roederer M, ... ... Scanga CA, et al. Intravenous BCG induces a more potent airway and lung immune response than intradermal BCG in SIV-infected macaques . Biorxiv : the Preprint Server For Biology. PMID 39091805 DOI: 10.1101/2024.07.17.603921  0.599
2024 Bobak CA, Stevenson KAJM, Sun N, Khan MS, Azmir J, Beccaria M, Tomko JA, Fillmore D, Scanga CA, Lin PL, Flynn JL, Hill JE. Defining a core breath profile for healthy, non-human primates. Scientific Reports. 14: 17031. PMID 39043722 DOI: 10.1038/s41598-024-64910-y  0.485
2024 Khan RMN, Ahn YM, Marriner GA, Via LE, D'Hooge F, Seo Lee S, Yang N, Basuli F, White AG, Tomko JA, Frye LJ, Scanga CA, Weiner DM, Sutphen ML, Schimel DM, et al. Distributable, metabolic PET reporting of tuberculosis. Nature Communications. 15: 5239. PMID 38937448 DOI: 10.1038/s41467-024-48691-6  0.523
2024 Simonson AW, Zeppa JJ, Bucsan AN, Chao MC, Pokkali S, Hopkins F, Chase MR, Vickers AJ, Sutton MS, Winchell CG, Myers AJ, Ameel CL, Kelly R, Krouse B, Hood LE, ... ... Scanga CA, et al. CD4 T cells and CD8α+ lymphocytes are necessary for intravenous BCG-induced protection against tuberculosis in macaques. Biorxiv : the Preprint Server For Biology. PMID 38798646 DOI: 10.1101/2024.05.14.594183  0.618
2024 Nambulli S, Escriou N, Rennick LJ, Demers MJ, Tilston-Lunel NL, McElroy AK, Barbeau DJ, Crossland NA, Hoehl RM, Schrauf S, White AG, Borish HJ, Tomko JA, Frye LJ, Scanga CA, et al. A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: protection of African green monkeys from COVID-19 disease. Journal of Virology. e0176223. PMID 38563762 DOI: 10.1128/jvi.01762-23  0.532
2024 Larson EC, Ellis-Connell AL, Rodgers MA, Gubernat AK, Gleim JL, Moriarty RV, Balgeman AJ, Ameel CL, Jauro S, Tomko JA, Kracinovsky KB, Maiello P, Borish HJ, White AG, Klein E, ... ... Scanga CA, et al. Author Correction: Intravenous Bacille Calmette-Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis. Nature Microbiology. PMID 38355766 DOI: 10.1038/s41564-024-01631-y  0.584
2023 Bromley JD, Ganchua SKC, Nyquist SK, Maiello P, Chao M, Borish HJ, Rodgers M, Tomko J, Kracinovsky K, Mugahid D, Nguyen S, Wang D, Rosenberg JM, Klein EC, Gideon HP, ... ... Scanga CA, et al. CD4 T cells are homeostatic regulators during reinfection. Biorxiv : the Preprint Server For Biology. PMID 38187598 DOI: 10.1101/2023.12.20.572669  0.568
2023 Winchell CG, Nyquist SK, Chao MC, Maiello P, Myers AJ, Hopkins F, Chase M, Gideon HP, Patel KV, Bromley JD, Simonson AW, Floyd-O'Sullivan R, Wadsworth M, Rosenberg JM, Uddin R, ... ... Scanga CA, et al. CD8+ lymphocytes are critical for early control of tuberculosis in macaques. The Journal of Experimental Medicine. 220. PMID 37843832 DOI: 10.1084/jem.20230707  0.563
2023 Larson EC, Ellis-Connell AL, Rodgers MA, Gubernat AK, Gleim JL, Moriarty RV, Balgeman AJ, Ameel CL, Jauro S, Tomko JA, Kracinovsky KB, Maiello P, Borish HJ, White AG, Klein E, ... ... Scanga CA, et al. Intravenous Bacille Calmette-Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis. Nature Microbiology. PMID 37814073 DOI: 10.1038/s41564-023-01503-x  0.621
2023 Tenório de Menezes YK, Eto C, de Oliveira J, Larson EC, Mendes DAGB, Dias GBM, Delgobo M, Gubernat AK, Gleim JL, Munari EL, Starick M, Ferreira F, Mansur DS, Costa DL, Scanga CA, et al. The Endogenous Retinoic Acid Receptor Pathway Is Exploited by Mycobacterium tuberculosis during Infection, Both In Vitro and In Vivo. Journal of Immunology (Baltimore, Md. : 1950). PMID 37395686 DOI: 10.4049/jimmunol.2200555  0.381
2023 Khan RMN, Ahn YM, Marriner GA, Via LE, D'Hooge F, Lee SS, Yang N, Basuli F, White AG, Tomko JA, Frye LJ, Scanga CA, Weiner DM, Sutphen ML, Schimel DM, et al. Distributable, Metabolic PET Reporting of Tuberculosis. Biorxiv : the Preprint Server For Biology. PMID 37333343 DOI: 10.1101/2023.04.03.535218  0.507
2023 Budak M, Cicchese JM, Maiello P, Borish HJ, White AG, Chishti HB, Tomko J, Frye LJ, Fillmore D, Kracinovsky K, Sakal J, Scanga CA, Lin PL, Dartois V, Linderman JJ, et al. Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens. Plos Computational Biology. 19: e1010823. PMID 37319311 DOI: 10.1371/journal.pcbi.1010823  0.543
2023 Darrah PA, Zeppa JJ, Wang C, Irvine EB, Bucsan AN, Rodgers MA, Pokkali S, Hackney JA, Kamath M, White AG, Borish HJ, Frye LJ, Tomko J, Kracinovsky K, Lin PL, ... ... Scanga CA, et al. Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques. Cell Host & Microbe. PMID 37267955 DOI: 10.1016/j.chom.2023.05.006  0.58
2023 Larson E, Ellis-Connell A, Rodgers M, Gubernat A, Gleim J, Moriarty R, Balgeman A, Ameel C, Jauro S, Tomko J, Kracinovsky K, Maiello P, Borish H, White A, Klein E, ... ... Scanga C, et al. Vaccination with intravenous BCG protects macaques with pre-existing SIV infection from tuberculosis. Research Square. PMID 37090620 DOI: 10.21203/rs.3.rs-2802306/v1  0.631
2023 Larson EC, Ellis AL, Rodgers MA, Gubernat AK, Gleim JL, Moriarty RV, Balgeman AJ, Menezes YK, Ameel CL, Fillmore DJ, Pergalske SM, Juno JA, Maiello P, White AG, Borish HJ, ... ... Scanga CA, et al. Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques. Infection and Immunity. e0055822. PMID 37039653 DOI: 10.1128/iai.00558-22  0.362
2023 Grant NL, Kelly K, Maiello P, Abbott H, O'Connor S, Lin PL, Scanga CA, Flynn JL. Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas. Mbio. e0047723. PMID 37039646 DOI: 10.1128/mbio.00477-23  0.621
2022 Gideon HP, Hughes TK, Tzouanas CN, Wadsworth MH, Tu AA, Gierahn TM, Peters JM, Hopkins FF, Wei JR, Kummerlowe C, Grant NL, Nargan K, Phuah JY, Borish HJ, Maiello P, ... ... Scanga CA, et al. Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control. Immunity. PMID 35483355 DOI: 10.1016/j.immuni.2022.04.004  0.589
2022 Moriarty RV, Rodgers MA, Ellis AL, Balgeman AJ, Larson EC, Hopkins F, Chase MR, Maiello P, Fortune SM, Scanga CA, O'Connor SL. Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis. Microbiology Spectrum. e0172421. PMID 35467372 DOI: 10.1128/spectrum.01724-21  0.387
2021 Stammes MA, Lee JH, Meijer L, Naninck T, Doyle-Meyers LA, White AG, Borish HJ, Hartman AL, Alvarez X, Ganatra S, Kaushal D, Bohm RP, le Grand R, Scanga CA, Langermans JAM, et al. Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates. Trends in Molecular Medicine. PMID 34955425 DOI: 10.1016/j.molmed.2021.12.001  0.506
2021 Mattila JT, Beaino W, White AG, Nyiranshuti L, Maiello P, Tomko J, Frye LJ, Fillmore D, Scanga CA, Lin PL, Flynn JL, Anderson CJ. Retention of Cu-FLFLF, a Formyl Peptide Receptor 1-Specific PET Probe, Correlates with Macrophage and Neutrophil Abundance in Lung Granulomas from Cynomolgus Macaques. Acs Infectious Diseases. PMID 34255474 DOI: 10.1021/acsinfecdis.0c00826  0.549
2021 Larson EC, Ellis-Connell A, Rodgers MA, Balgeman AJ, Moriarty RV, Ameel CL, Baranowski TM, Tomko JA, Causgrove CM, Maiello P, O'Connor SL, Scanga CA. Pre-existing Simian Immunodeficiency Virus Infection Increases Expression of T Cell Markers Associated with Activation during Early Coinfection and Impairs TNF Responses in Granulomas. Journal of Immunology (Baltimore, Md. : 1950). PMID 34145063 DOI: 10.4049/jimmunol.2100073  0.382
2020 Drusano GL, Duncanson B, Scanga CA, Kim S, Schmidt S, Neely MN, Yamada WM, Vicchiarelli M, Peloquin CA, Louie A. Developing new drugs for the therapy of : What information do we get from pre-clinical animal models? Antimicrobial Agents and Chemotherapy. PMID 32958720 DOI: 10.1128/Aac.01376-20  0.338
2020 Hartman AL, Nambulli S, McMillen CM, White AG, Tilston-Lunel NL, Albe JR, Cottle E, Dunn MD, Frye LJ, Gilliland TH, Olsen EL, O'Malley KJ, Schwarz MM, Tomko JA, Walker RC, ... ... Scanga CA, et al. SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts. Plos Pathogens. 16: e1008903. PMID 32946524 DOI: 10.1371/Journal.Ppat.1008903  0.591
2020 Kim S, Scanga CA, Miranda Silva C, Zimmerman M, Causgrove C, Stein B, Dartois V, Peloquin CA, Graham E, Louie A, Flynn JL, Schmidt S, Drusano GL. Pharmacokinetics of tedizolid, sutezolid, and sutezolid-M1 in non-human primates. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105421. PMID 32531349 DOI: 10.1016/J.Ejps.2020.105421  0.572
2020 Ellis AL, Balgeman AJ, Larson EC, Rodgers MA, Ameel C, Baranowski T, Kannal N, Maiello P, Juno JA, Scanga CA, O'Connor SL. MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection. Plos Pathogens. 16: e1008585. PMID 32433713 DOI: 10.1371/Journal.Ppat.1008585  0.426
2020 Darrah PA, Zeppa JJ, Maiello P, Hackney JA, Wadsworth MH, Hughes TK, Pokkali S, Swanson PA, Grant NL, Rodgers MA, Kamath M, Causgrove CM, Laddy DJ, Bonavia A, Casimiro D, ... ... Scanga CA, et al. Prevention of tuberculosis in macaques after intravenous BCG immunization. Nature. 577: 95-102. PMID 31894150 DOI: 10.1038/S41586-019-1817-8  0.664
2019 Darrah PA, DiFazio RM, Maiello P, Gideon HP, Myers AJ, Rodgers MA, Hackney JA, Lindenstrom T, Evans T, Scanga CA, Prikhodko V, Andersen P, Lin PL, Laddy D, Roederer M, et al. Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques. Npj Vaccines. 4: 21. PMID 31149352 DOI: 10.1038/s41541-019-0113-9  0.621
2018 Rodgers MA, Ameel C, Ellis-Connell AL, Balgeman AJ, Maiello P, Barry GL, Friedrich TC, Klein E, O'Connor SL, Scanga CA. Pre-existing SIV Infection Increases Susceptibility to Tuberculosis in Mauritian Cynomolgus Macaques. Infection and Immunity. PMID 30224552 DOI: 10.1128/Iai.00565-18  0.477
2018 Mellors TR, Nasir M, Franchina FA, Smolinska A, Blanchet L, Flynn J, Tomko JA, O'Malley MJ, Scanga CA, Lin PL, Wagner J, Hill JE. Identification of Mycobacterium tuberculosis using volatile biomarkers in culture and exhaled breath. Journal of Breath Research. PMID 29910196 DOI: 10.1088/1752-7163/Aacd18  0.628
2017 Maiello P, DiFazio RM, Cadena AM, Rodgers MA, Lin PL, Scanga CA, Flynn JL. Rhesus macaques are more susceptible to progressive tuberculosis than cynomolgus macaques: A quantitative comparison. Infection and Immunity. PMID 28947646 DOI: 10.1128/Iai.00505-17  0.655
2017 White AG, Maiello P, Coleman MT, Tomko JA, Frye LJ, Scanga CA, Lin PL, Flynn JL. Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates. Journal of Visualized Experiments : Jove. PMID 28930979 DOI: 10.3791/56375  0.621
2017 Mattila JT, Beaino W, Maiello P, Coleman MT, White AG, Scanga CA, Flynn JL, Anderson CJ. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1-Expressing Immune Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 28592427 DOI: 10.4049/Jimmunol.1700231  0.59
2017 Rockwood N, Costa DL, Amaral EP, Du Bruyn E, Kubler A, Gil-Santana L, Fukutani KF, Scanga CA, Flynn JL, Jackson SH, Wilkinson KA, Bishai WR, Sher A, Wilkinson RJ, Andrade BB. Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes. Frontiers in Immunology. 8: 542. PMID 28553288 DOI: 10.3389/Fimmu.2017.00542  0.608
2017 Ellis A, Balgeman A, Rodgers M, Updike C, Tomko J, Maiello P, Scanga CA, O'Connor SL. Characterization of T cells specific for CFP-10 and ESAT-6 in M. tuberculosis-infected Mauritian Cynomolgus Macaques. Infection and Immunity. PMID 28115506 DOI: 10.1128/Iai.01009-16  0.493
2017 Wonderlich ER, Swan ZD, Bissel SJ, Hartman AL, Carney JP, O'Malley KJ, Obadan AO, Santos J, Walker R, Sturgeon TJ, Frye LJ, Maiello P, Scanga CA, Bowling JD, Bouwer AL, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. Journal of Immunology (Baltimore, Md. : 1950). PMID 28062701 DOI: 10.4049/Jimmunol.1601770  0.546
2017 Mellors TR, Blanchet L, Flynn JL, Tomko J, O'Malley M, Scanga CA, Lin PL, Hill JE. A new method to evaluate macaque health using exhaled breath: A case study of M. tuberculosis in a BSL-3 setting. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00888.2016. PMID 28057819 DOI: 10.1152/Japplphysiol.00888.2016  0.619
2016 Marinho FV, Fahel JS, Scanga CA, Gomes MT, Guimarães G, Carvalho GR, Morales SV, Báfica A, Oliveira SC. Lack of IL-1 Receptor-Associated Kinase-4 Leads to Defective Th1 Cell Responses and Renders Mice Susceptible to Mycobacterial Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 27439514 DOI: 10.4049/Jimmunol.1502157  0.387
2015 Levine DM, Dutta NK, Eckels J, Scanga C, Stein C, Mehra S, Kaushal D, Karakousis PC, Salamon H. A tuberculosis ontology for host systems biology. Tuberculosis (Edinburgh, Scotland). 95: 570-4. PMID 26190839 DOI: 10.1016/J.Tube.2015.05.012  0.386
2014 Coleman MT, Chen RY, Lee M, Lin PL, Dodd LE, Maiello P, Via LE, Kim Y, Marriner G, Dartois V, Scanga C, Janssen C, Wang J, Klein E, Cho SN, et al. PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis. Science Translational Medicine. 6: 265ra167. PMID 25473035 DOI: 10.1126/Scitranslmed.3009500  0.612
2014 Scanga CA, Flynn JL. Modeling tuberculosis in nonhuman primates. Cold Spring Harbor Perspectives in Medicine. 4: a018564. PMID 25213189 DOI: 10.1101/Cshperspect.A018564  0.656
2014 Darrah PA, Bolton DL, Lackner AA, Kaushal D, Aye PP, Mehra S, Blanchard JL, Didier PJ, Roy CJ, Rao SS, Hokey DA, Scanga CA, Sizemore DR, Sadoff JC, Roederer M, et al. Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge. Journal of Immunology (Baltimore, Md. : 1950). 193: 1799-811. PMID 25024382 DOI: 10.4049/Jimmunol.1400676  0.473
2014 Scanga CA, Lopresti BJ, Tomko J, Frye LJ, Coleman TM, Fillmore D, Carney JP, Lin PL, Flynn JL, Gardner CL, Sun C, Klimstra WB, Ryman KD, Reed DS, Fisher DJ, et al. In vivo imaging in an ABSL-3 regional biocontainment laboratory. Pathogens and Disease. 71: 207-12. PMID 24838691 DOI: 10.1111/2049-632X.12186  0.544
2013 Lin PL, Coleman T, Carney JP, Lopresti BJ, Tomko J, Fillmore D, Dartois V, Scanga C, Frye LJ, Janssen C, Klein E, Barry CE, Flynn JL. Radiologic responses in cynomolgous macaques for assessing tuberculosis chemotherapy regimens. Antimicrobial Agents and Chemotherapy. PMID 23796926 DOI: 10.1128/Aac.00277-13  0.615
2012 Rahman S, Magalhaes I, Rahman J, Ahmed RK, Sizemore DR, Scanga CA, Weichold F, Verreck F, Kondova I, Sadoff J, Thorstensson R, Spångberg M, Svensson M, Andersson J, Maeurer M, et al. Prime-boost vaccination with rBCG/rAd35 enhances CD8⁺ cytolytic T-cell responses in lesions from Mycobacterium tuberculosis-infected primates. Molecular Medicine (Cambridge, Mass.). 18: 647-58. PMID 22396020 DOI: 10.2119/Molmed.2011.00222  0.466
2010 Scanga CA, Flynn JL. Mycobacterial infections and the inflammatory seesaw. Cell Host & Microbe. 7: 177-9. PMID 20227659 DOI: 10.1016/J.Chom.2010.03.003  0.544
2009 Sun R, Skeiky YA, Izzo A, Dheenadhayalan V, Imam Z, Penn E, Stagliano K, Haddock S, Mueller S, Fulkerson J, Scanga C, Grover A, Derrick SC, Morris S, Hone DM, et al. Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis. Vaccine. 27: 4412-23. PMID 19500523 DOI: 10.1016/J.Vaccine.2009.05.048  0.402
2008 Magalhaes I, Sizemore DR, Ahmed RK, Mueller S, Wehlin L, Scanga C, Weichold F, Schirru G, Pau MG, Goudsmit J, Kühlmann-Berenzon S, Spångberg M, Andersson J, Gaines H, Thorstensson R, et al. rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector. Plos One. 3: e3790. PMID 19023426 DOI: 10.1371/Journal.Pone.0003790  0.448
2007 Scanga CA, Bafica A, Sher A. Viral gene expression in HIV transgenic mice is activated by Mycobacterium tuberculosis and suppressed after antimycobacterial chemotherapy. The Journal of Infectious Diseases. 195: 246-54. PMID 17191170 DOI: 10.1086/510244  0.436
2005 Bafica A, Scanga CA, Feng CG, Leifer C, Cheever A, Sher A. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. The Journal of Experimental Medicine. 202: 1715-24. PMID 16365150 DOI: 10.1084/Jem.20051782  0.395
2005 Bafica A, Scanga CA, Serhan C, Machado F, White S, Sher A, Aliberti J. Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. The Journal of Clinical Investigation. 115: 1601-6. PMID 15931391 DOI: 10.1172/Jci23949  0.492
2005 Feng CG, Jankovic D, Kullberg M, Cheever A, Scanga CA, Hieny S, Caspar P, Yap GS, Sher A. Maintenance of pulmonary Th1 effector function in chronic tuberculosis requires persistent IL-12 production. Journal of Immunology (Baltimore, Md. : 1950). 174: 4185-92. PMID 15778379 DOI: 10.4049/Jimmunol.174.7.4185  0.447
2004 Scanga CA, Bafica A, Feng CG, Cheever AW, Hieny S, Sher A. MyD88-deficient mice display a profound loss in resistance to Mycobacterium tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression. Infection and Immunity. 72: 2400-4. PMID 15039368 DOI: 10.1128/Iai.72.4.2400-2404.2004  0.424
2003 Lazarevic V, Myers AJ, Scanga CA, Flynn JL. CD40, but not CD40L, is required for the optimal priming of T cells and control of aerosol M. tuberculosis infection. Immunity. 19: 823-35. PMID 14670300 DOI: 10.1016/S1074-7613(03)00324-8  0.733
2003 Feng CG, Scanga CA, Collazo-Custodio CM, Cheever AW, Hieny S, Caspar P, Sher A. Mice lacking myeloid differentiation factor 88 display profound defects in host resistance and immune responses to Mycobacterium avium infection not exhibited by Toll-like receptor 2 (TLR2)- and TLR4-deficient animals. Journal of Immunology (Baltimore, Md. : 1950). 171: 4758-64. PMID 14568952 DOI: 10.4049/Jimmunol.171.9.4758  0.362
2003 Báfica A, Scanga CA, Schito ML, Hieny S, Sher A. Cutting edge: in vivo induction of integrated HIV-1 expression by mycobacteria is critically dependent on Toll-like receptor 2. Journal of Immunology (Baltimore, Md. : 1950). 171: 1123-7. PMID 12874196 DOI: 10.4049/Jimmunol.171.3.1123  0.348
2002 Brennan PJ, Terwilliger T, Barry CE, Manca C, Su H, Reed M, Rutter K, Domenech P, Kaplan G, Li YJ, Wagner D, Bermudez LE, Bodnar K, Flynn J, Campos-Neto A, ... ... Scanga C, et al. The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th annual research conference, New Orleans, Louisiana, USA, 15-17 July 2001 Tuberculosis. 82: 113-135. PMID 12408170 DOI: 10.1054/Tube.2002.0329  0.63
2002 Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 5997-6001. PMID 12055206 DOI: 10.4049/Jimmunol.168.12.5997  0.312
2001 Scanga CA, Mohan VP, Tanaka K, Alland D, Flynn JL, Chan J. The inducible nitric oxide synthase locus confers protection against aerogenic challenge of both clinical and laboratory strains of Mycobacterium tuberculosis in mice. Infection and Immunity. 69: 7711-7. PMID 11705952 DOI: 10.1128/Iai.69.12.7711-7717.2001  0.638
2001 Mohan VP, Scanga CA, Yu K, Scott HM, Tanaka KE, Tsang E, Tsai MM, Flynn JL, Chan J. Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology. Infection and Immunity. 69: 1847-55. PMID 11179363 DOI: 10.1128/Iai.69.3.1847-1855.2001  0.682
2000 Scanga CA, Mohan VP, Yu K, Joseph H, Tanaka K, Chan J, Flynn JL. Depletion of CD4(+) T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon gamma and nitric oxide synthase 2. The Journal of Experimental Medicine. 192: 347-58. PMID 10934223 DOI: 10.1084/Jem.192.3.347  0.643
2000 Serbina NV, Liu CC, Scanga CA, Flynn JL. CD8+ CTL from lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages. Journal of Immunology (Baltimore, Md. : 1950). 165: 353-63. PMID 10861072 DOI: 10.4049/Jimmunol.165.1.353  0.789
1999 Scanga CA, Mohan VP, Joseph H, Yu K, Chan J, Flynn JL. Reactivation of latent tuberculosis: variations on the Cornell murine model. Infection and Immunity. 67: 4531-8. PMID 10456896 DOI: 10.1128/Iai.67.9.4531-4538.1999  0.659
1998 Flynn JL, Scanga CA, Tanaka KE, Chan J. Effects of aminoguanidine on latent murine tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 160: 1796-803. PMID 9469439  0.615
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