Ryan P. Bender, Ph.D. - Publications

2007 Vanderbilt University, Nashville, TN 
Biochemistry, Toxicology

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2008 Bender RP, Jablonksy MJ, Shadid M, Romaine I, Dunlap N, Anklin C, Graves DE, Osheroff N. Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity. Biochemistry. 47: 4501-9. PMID 18355043 DOI: 10.1021/bi702019z  1
2007 Wilstermann AM, Bender RP, Godfrey M, Choi S, Anklin C, Berkowitz DB, Osheroff N, Graves DE. Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme. Biochemistry. 46: 8217-25. PMID 17580961 DOI: 10.1021/bi700272u  1
2007 Bender RP, Osheroff N. Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate. Chemical Research in Toxicology. 20: 975-81. PMID 17516663 DOI: 10.1021/tx700062t  1
2007 Bender RP, Ham AJ, Osheroff N. Quinone-induced enhancement of DNA cleavage by human topoisomerase IIalpha: adduction of cysteine residues 392 and 405. Biochemistry. 46: 2856-64. PMID 17298034 DOI: 10.1021/bi062017l  1
2006 Bender RP, Lehmler HJ, Robertson LW, Ludewig G, Osheroff N. Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate. Biochemistry. 45: 10140-52. PMID 16906772 DOI: 10.1021/bi0524666  1
2005 Lindsey RH, Bender RP, Osheroff N. Stimulation of topoisomerase II-mediated DNA cleavage by benzene metabolites. Chemico-Biological Interactions. 153: 197-205. PMID 15935817 DOI: 10.1016/j.cbi.2005.03.035  1
2005 Lindsey RH, Bender RP, Osheroff N. Effects of benzene metabolites on DNA cleavage mediated by human topoisomerase II alpha: 1,4-hydroquinone is a topoisomerase II poison. Chemical Research in Toxicology. 18: 761-70. PMID 15833037 DOI: 10.1021/tx049659z  1
2004 Bender RP, Lindsey RH, Burden DA, Osheroff N. N-acetyl-p-benzoquinone imine, the toxic metabolite of acetaminophen, is a topoisomerase II poison. Biochemistry. 43: 3731-9. PMID 15035644 DOI: 10.1021/bi036107r  1
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